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Acne Vulgaris
A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
Subtype terms (1)
More specific conditions that are subtypes of Acne Vulgaris in the MeSH hierarchy.
- Acne Conglobata
1 drug approved
Drugs by status
Approved for this indication (34)
- sarecycline
- adapalene
- tazarotene
- clascoterone
- doxycycline
- folic acid
- ethinyl estradiol
- drospirenone
- niacin
- dapsone
- nicotinamide
- norgestimate
- clindamycin
- resorcinol
- sulfacetamide
- tea
- meclocycline
- minocycline
- pentetic acid
- ofloxacin
- isotretinoin
- alitretinoin
- methylfolate
- tretinoin
- hydroxocobalamin
- erythromycin
- benzoyl peroxide
- trifarotene
- sarecycline hydrochloride
- glycolic acid
- +4 more
Phase 4 trials (34)
- metformin
- propofol
- vitamin d3
- tetracaine
- aloe vera
- prednisone
- dezocine
- ethanol
- sevoflurane
- etomidate
- esketamine
- Eucalyptol
- desogestrel
- modulen
- atorvastatin
- lidocaine
- salicylic acid
- propylene glycol
- remimazolam
- hyaluronic acid
- resveratrol
- azelaic acid
- spironolactone
- palmityl alcohol
- silymarin
- sodium chloride
- phenytoin
- tetracycline
- sulfur
- sodium monododecyl sulfate
- +4 more
Phase 3 trials (62)
- sodium fluoride (18F)
- montelukast
- aminolevulinic acid
- astaxanthin
- urea
- b244
- procaine benzylpenicillin
- busulfan
- ceramide
- clavulanate
- alfentanil
- aciclovir
- naltrexone
- zopiclone
- icosapent ethyl
- ulobetasol propionate
- platelet-rich plasma
- levamisole
- olumacostat glasaretil
- piperacillin
- berotralstat
- propolis
- ramelteon
- allogeneic hematopoietic stem cells
- Berdazimer
- sirolimus
- cyclosporine
- mycophenolate
- cyclophosphamide
- sufentanil
- +32 more
Phase 2 trials (72)
- jnj 10229570
- mtc896
- retinoic acid
- ksl-2
- cmv-specific t-cells
- afamelanotide
- Dimethylcurcumin
- auriclosene
- bli1100
- apremilast
- cjm112
- doxorubicin
- cannabidiol
- foscarnet
- ingenol mebutate
- idp-107
- insulin human
- bleomycin
- ganciclovir
- iodine
- bmx-010
- ivermectin
- lemuteporfin
- dronabinol
- human papillomavirus quadrivalent (types 6, 11, 16 and 18) vaccine, recombinant
- methyl aminolevulinate
- rimabotulinumtoxinB
- vitamin c
- omiganan
- vincristine
- +42 more
Phase 1 trials (26)
- gsk1940029
- azadirachta indica
- e1m184v
- gsk3008356
- incomplete freund's adjuvant
- amoxicillin
- lappa arctium
- tetanus-cmv fusion peptide vaccine
- pantothenic acid
- ebna1 c-terminal/lmp2 chimeric protein-expressing recombinant modified vaccinia ankara vaccine
- akkermansia muciniphila
- rituximab
- agatolimod
- moxifloxacin
- timolol
- lumateperone
- water
- delamanid
- dihydroartemisinin
- nb01
- COVID-19 convalescent plasma
- c. acnes vaccine
- gt20029
- pf-07905428
- clostridium beijerinckii
- tvb-3567
Other trials (56)
- tin difluoride
- blinatumomab
- ketamine
- cocoa bean
- effaclar
- essential oils
- flutamide
- gabapentin
- gelatin
- manuka honey
- theanine
- tryptophan
- lipohydroxy acid
- lupeol
- hydroxyapatite silica
- m. alternifolia
- acetaminophen
- donepezil
- silicon phthalocyanine
- bupivacaine
- butenyl ala
- pentoxifylline
- glucose
- collagen
- valaciclovir
- cellulose
- zolpidem
- apple
- bakuchiol
- bifidobacteria adolescentis bd1
- +26 more
Organizations
Organization Involved with Phase 4 Indications (73)
- Novelion Therapeutics
- Medicis
- Bausch Health Companies
- Stiefel Laboratories
- Sanofi
- GlaxoSmithKline
- GWT-TUD GmbH
- KGL, Inc.
- Maruho Co., Ltd.
- MedDerm Associates
- Parexel
- Derm Research @ 888 Inc.
- Derm Research, PLLC
- Zurita Laboratorio Farmaceutico Ltda.
- Warner Chilcott
- University of Pennsylvania
- University of London
- Harvard University
- Henry Ford Health System
- New York University
- Thomas Jefferson University
- University of Magdeburg
- University of Tehran
- University of Aberdeen
- Wake Forest University
- Yardley Dermatology Associates
- Assiut University
- Dermatology Specialists Research
- University of California, Davis
- University of Cincinnati
- +43 more
Organization Involved with Phase 3 Indications (57)
- Fougera
- Actavis
- Ache Laboratorios Farmaceuticos S.A.
- Perrigo
- Akorn, Inc.
- AOBiome LLC
- Cassiopea SpA
- Cipher Pharmaceuticals Inc.
- Dow Pharmaceutical Sciences
- Foamix Ltd.
- G & W Laboratories Inc.
- Laboratorios Goulart S.A.
- Novan, Inc.
- Seegpharm S.A.
- Torrent Pharmaceuticals Limited
- Capstone Therapeutics
- Dermira, Inc.
- Sol-Gel Technologies, Ltd.
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- Cairo University
- Chulalongkorn University
- Faculdade de Medicina do ABC
- Kaiser Permanente
- Marmara University
- University of Kiel
- Wayne State University
- Ahvaz Jundishapur University of Medical Sciences
- University of California, Los Angeles
- Glenmark Pharmaceuticals
- Catawba Clinical Research
- +27 more
Organization Involved with Phase 2 Indications (61)
- DUSA Pharmaceuticals
- Anterios
- Celgene
- Novartis
- AndroScience Corp
- Aria Aesthetics Inc.
- BioWest Therapeutics Inc
- Braintree Laboratories
- Celtaxsys, Inc.
- Critical Therapeutics
- Cutanea Life Sciences, Inc.
- Elorac, Inc.
- Intrepid Therapeutics, Inc.
- M. Arkin 1999 Ltd.
- Mimetica Pty Limited
- Mundipharma
- Nexgen Pharma, Inc
- Orient Europharma Co., Ltd.
- Photocure
- Sponsor GmbH
- Therapeutics, Inc.
- Virginia Clinical Research, Inc.
- XBiotech, Inc.
- Xenon Pharmaceuticals Inc.
- Dermata Therapeutics
- Xoma
- Shahid Beheshti University of Medical Sciences
- Chang Gung University
- DeNova Research
- Johns Hopkins University
- +31 more
Organization Involved with Phase 1 Indications (13)
Organization Involved with Other Experimental Indications (74)
- Cosmetique Active International
- L'Oreal
- Centro Dermatológico Dr. Ladislao de la Pascua
- Andhra Medical College
- Azad University
- National Cheng Kung University
- National Yang-Ming University
- Seoul National University
- University of Miami
- Fudan University
- University of Chicago
- University of Copenhagen
- University of Freiburg
- Jiao Tong University
- Stephens & Associates, Inc
- Jehangir Clinical Development Centre Pvt. Ltd.
- Bharati Vidyapeeth University
- BJ Govt Medical College & Sassoon General Hospitals, Pune
- Jubilant Clinsys, Inc
- Lotus Labs
- Indu Shree Clinic
- Bhagwan Mahaveer Jain Hospital
- Sardesai Clinic
- Bowring & Lady Curzon Hospital
- Dhanawantari Polyclinic
- MS Clinical Research Pvt. Ltd.
- G.M Modi Hospital
- Dayal Clinic
- J.S.S. Medical College Hospital
- L.T.M. Medical College & General Hospital
- +44 more