aloe vera
Botanicalexperimental
Aloe vera is a succulent plant species of the genus Aloe. It is widely distributed, and is considered an invasive species in many world regions. — Wikipedia
Clinical trial activity
59 trials · 61 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
11
Phase 3
11
Phase 4
11
Earliest trial started Jun 30, 2005 (NCT00219466)
Timeline
Indications
Approved for
Studied for
- Acne Vulgaris · Phase 4
- Breast Neoplasms · Early Phase 1
- Chronic Periodontitis · Phase 4
- Colitis, Ulcerative · Early Phase 1
- Cystitis, Interstitial · Early Phase 1
- Dental Caries · Phase 2
- Diabetes Mellitus · Phase 4
- Diaper Rash · Phase 4
- Esophageal Neoplasms · Phase 3
- Extrapyramidal Tracts · Phase 4
- Frostbite · Phase 4
- Gastroesophageal Reflux · Phase 4
- Gingivitis · Phase 2
- Halitosis · Phase 1/Phase 2
- Head and Neck Neoplasms · Phase 3
- Hemorrhoids · Phase 4
- Laryngeal Neoplasms · Phase 3
- Mediastinal Neoplasms · Phase 3
- Metabolic Syndrome · Phase 2/Phase 3
- Mouth Neoplasms · Phase 3
- Mucositis · Phase 3
- Neoplasms · Phase 3
- Oral Submucous Fibrosis · Phase 3
- Oral Ulcer · Phase 4
- Oropharyngeal Neoplasms · Phase 3
- Periapical Diseases · Phase 1
- Periodontal Diseases · Phase 2/Phase 3
- Periodontitis · Phase 4
- Prostatic Hyperplasia · Phase 1
- Radiodermatitis · Phase 3
- Tinea Versicolor · Phase 4
- Vitamin D Deficiency · Phase 2
- Wounds and Injuries · Phase 4
- Xerostomia · Phase 3
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAloe vera ↗
- NCATSW21O437517 ↗
- ChEMBLCHEMBL2108221 ↗
- NCATSZY81Z83H0X ↗
- NCATSV5VD430YW9 ↗
- NCATS575DY8C1ER ↗
Also known as
- aloe
- aloe
- aloe barbadensis miller
- aloe vera
- aloe vera
- dermotivin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07084194 | N/A | Sep 10, 2025 | Minia University |
| NCT07057557 | N/A | Aug 5, 2025 | King Edward Medical University |
| NCT06862687 | N/A | May 1, 2024 | Ataturk University |
| NCT06266494 | Phase 4 | Mar 1, 2024 | Department of Defense, University of Colorado, Denver |
| NCT06243601 | Phase 1 | Nov 30, 2023 | Islamabad Medical and Dental College |
| NCT06862817 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2023 | Minia University |
| NCT06170333 | Phase 4 | Aug 25, 2023 | Padjadjaran University |
| NCT05885906 | Phase 3 | Jul 24, 2023 | Ain Shams University |
| NCT07065682 | Phase 1 | Jul 1, 2023 | Diponegoro University |
| NCT06879366 | Phase 4 | Jun 1, 2023 | October 6 University |
| NCT06757270 | N/A | Mar 7, 2023 | Ain Shams University |
| NCT05578638 | N/A | Oct 1, 2022 | Mansoura University |
| NCT06041178 | Phase 4 | Sep 30, 2022 | Beirut Arab University |
| NCT05223127 | N/A | Aug 1, 2022 | KTO Karatay University |
| NCT05510050 | N/A | May 13, 2022 | Mannatech, University of Memphis |
| NCT05369234 | Phase 3 | Jan 20, 2022 | Thompson Cancer Survival Center |
| NCT06377657 | N/A | Jan 15, 2022 | University of Nis |
| NCT04734106 | Early Phase 1 (Phase 1) | Dec 31, 2021 | Desert Harvest, Wake Forest University |
| NCT04942470 | N/A | Mar 11, 2021 | Haydarpasa Numune State Hospital, Istanbul University |
| NCT05327049 | N/A | Feb 1, 2021 | Al Azhar University |
Showing 20 of 59 trials
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Organizations
Research & Development (61)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cairo University | Academic/Hospital | 3 | 3 | 2 | 2017 |
| Ghent University | Academic/Hospital | 3 | 3 | 2 | 2006 |
| Government Dental College and Research Institute, Bangalore | Academic/Hospital | 3 | 3 | 1 | 2014 |
| Ain Shams University | Academic/Hospital | 2 | 2 | 2 | 2023 |
| Azad University | Academic/Hospital | 2 | 2 | 2 | 2013 |
| Dr. D. Y. Patil Dental College & Hospital | Academic/Hospital | 2 | 2 | 2 | 2014 |
| Mannatech | For profit | 2 | 0 | 1 | 2018 |
| Mansoura University | Academic/Hospital | 2 | 2 | 2 | 2020 |
| Minia University | Academic/Hospital | 2 | 2 | 2 | 2023 |
| University of Memphis | Academic/Hospital | 2 | 2 | 1 | 2018 |
| University of Roma La Sapienza | Academic/Hospital | 2 | 1 | 1 | 2017 |
| Aboca | For profit | 1 | 1 | 1 | 2017 |
| Al Azhar University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Alexandria University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Ataturk University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Beirut Arab University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| BMR Genomics | For profit | 1 | 0 | 1 | 2017 |
| Calmino group AB | For profit | 1 | 0 | 1 | 2010 |
| Clinpharma | For profit | 1 | 0 | 1 | 2017 |
| Damascus University | Academic/Hospital | 1 | 1 | 1 | 2019 |
61 organizations
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