glycolic acid

Small moleculeexperimental

Glycolic acid is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water. It is used in various skin-care products. Glycolic acid is widespread in nature. A glycolate is a salt or ester of glycolic acid. — Wikipedia

Clinical trial activity

12 trials · 14 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
5
Phase 3
1
Phase 4
4

Earliest trial started Feb 1, 2006 (NCT01589523)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 3 Sponsor(trial)

2010s

  1. Jan 1, 2013

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2017

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

O=C(O)CO
Mol. weight
76.05 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Single Stereoisomer
Inorganic
No
Polymer
Yes

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 2-hydroxyacetic acid
  • 2-hydroxyacetic acid
  • 2-hydroxyethanoic acid
  • 2-hydroxyethanoic acid
  • alpha-hydroxyacetic acid
  • alpha-hydroxyacetic acid
  • glycolate
  • glycolic acid
  • glycolic acid
  • glycolic acid
  • glycolic acid
  • glycolic acid
  • glycolic acid
  • glycolic acid
  • glycolic acid, 1-(14)c-labeled
  • glycolic acid, 2-(14)c-labeled
  • glycolic acid, calcium salt
  • glycolic acid, monoammonium salt
  • glycolic acid, monolithium salt
  • glycolic acid, monopotassium salt
  • glycolic acid, monosodium salt
  • glycolic acid, potassium salt
  • glycollic acid
  • glycollic acid
  • hydroxyacetic acid
  • hydroxyacetic acid
  • hydroxyacetic acid
  • hydroxyacetic acid
  • hydroxyethanoic acid
  • hydroxyethanoic acid
  • hydroxyethanoic acid
  • potassium glycolate
  • α-hydroxyacetic acid
  • α-hydroxyacetic acid

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05471947Phase 4Sep 1, 2022Main Line Center for Laser Surgery
NCT05362500Phase 1Jun 1, 2021Government of Pakistan
NCT03153852Phase 4Dec 15, 2017Assiut University
NCT02812719Early Phase 1 (Phase 1)Dec 1, 2017Boston University
NCT03192306Phase 2Jul 5, 2017Accelovance, Benu BioPharma, Inc., Optimal Research, Topical Remedy
NCT02126657Phase 2May 1, 2014National University of Singapore
NCT02126644Phase 2May 1, 2014National University of Singapore
NCT02052752Phase 4Feb 1, 2014GlaxoSmithKline
NCT01985321Phase 2Nov 1, 2013Benu BioPharma, Inc., Topical Remedy
NCT01289171N/AJan 1, 2009NeoStrata Company, Inc., University of Pennsylvania
NCT00472966Phase 4Nov 1, 2006Galderma
NCT01589523Phase 3Feb 1, 2006University of Cincinnati
Showing 12 of 12 trials
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Organizations

Research & Development (14)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Benu BioPharma, Inc.For profit2012013
National University of SingaporeAcademic/Hospital2212014
Topical RemedyFor profit2212013
AccelovanceFor profit1012017
Assiut UniversityAcademic/Hospital1112017
Boston UniversityAcademic/Hospital1112017
GaldermaFor profit1112006
GlaxoSmithKlineFor profit1112014
Government of PakistanGovernment1112021
Main Line Center for Laser SurgeryAcademic/Hospital1112022
NeoStrata Company, Inc.For profit1012009
Optimal ResearchFor profit1012017
University of CincinnatiAcademic/Hospital1112006
University of PennsylvaniaAcademic/Hospital1112009
14 organizations
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