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astaxanthin

Small moleculeexperimental

Astaxanthin is a keto-carotenoid within a group of chemical compounds known as carotenoids or terpenes. Astaxanthin is a metabolite of zeaxanthin and canthaxanthin, containing both hydroxyl and ketone functional groups. — Wikipedia

Clinical trial activity

44 trials · 51 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
6
Phase 3
4
Phase 4
5

Earliest trial started Mar 23, 2010 (NCT03945526)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2011

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2018

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetOTHER

    Antioxidant, anti-inflammatory and antiapoptotic activities

  • Unspecified targetAntioxidant

    antioxidant

Chemistry & pharmacology

Loading structure…

SMILES

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)[C@@H](O)CC2(C)C)C(C)(C)C[C@H](O)C1=O
Mol. weight
596.85 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 3,3'-dihydroxy-beta-carotene-4,4'-dione
  • astaxanthin
  • astaxanthin
  • astaxanthin
  • astaxanthin
  • astaxanthine
  • bioastin
  • e-astaxanthin
  • liposomal astaxanthin

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07063056N/AJul 18, 2025Medinutra LLC
NCT06589128N/ASep 10, 2024Univerisiti Sains Malaysia
NCT06460181Phase 4Aug 1, 2024University of North Alabama
NCT06642363Phase 1Jul 22, 2024Isfahan University
NCT06429059Phase 2Jun 12, 2024Duke University, Temple University
NCT06334874Phase 4Apr 1, 2024Future University in Egypt
NCT05882084N/AJul 24, 2023Integrative Skin Science and Research
NCT05941949N/AJul 5, 2023Clinical Research Australia, Pharmanex
NCT05437601Phase 2Jul 31, 2022Bangladesh Medical University
NCT05376501N/AJun 8, 2022LycoRed Ltd., Nutrasource Diagnostics
NCT05138549Phase 2/Phase 3 (Phase 3)Jan 31, 2022Prisma Health
NCT05409092N/AJan 19, 2022Appalachian State University, LycoRed Ltd.
NCT05009810N/AAug 15, 2021Chulalongkorn University
NCT05282355N/AMay 12, 2021University of North Alabama
NCT04689984Phase 2/Phase 3 (Phase 3)Nov 3, 2020Duta Wacana Christian University, PT SOHO Global Health Tbk
NCT05508529N/AJul 1, 20203 Waves Wellness
NCT04249128Phase 3Jan 15, 2020Noho Health, ProofPilot
NCT04071977Phase 2Aug 31, 2019University of Guadalajara
NCT03991286N/AJul 31, 2019University of Tehran
NCT03664466N/AJan 31, 2019Saint Luke's Health System
Showing 20 of 44 trials
Page 1 / 3

Organizations

Research & Development (51)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of GuadalajaraAcademic/Hospital3322011
Instituto Mexicano del Seguro SocialGovernment2022011
LycoRed Ltd.For profit2112022
Menarini GroupFor profit2212017
Seoul National UniversityAcademic/Hospital2212010
Tel Aviv UniversityAcademic/Hospital2112014
University of North AlabamaAcademic/Hospital2222021
University of PerugiaAcademic/Hospital2212014
3 Waves WellnessAcademic/Hospital1112020
AjinomotoFor profit1112014
Algatechnologies Ltd.For profit1112018
Appalachian State UniversityAcademic/Hospital1112022
Astavita, Inc.For profit1112015
Bangladesh Medical UniversityAcademic/Hospital1112022
China Medical UniversityAcademic/Hospital1012018
Chulalongkorn UniversityAcademic/Hospital1112021
Clinical Research AustraliaAcademic/Hospital1012023
Cyanotech CorporationFor profit1112015
Duke UniversityAcademic/Hospital1112024
Duta Wacana Christian UniversityAcademic/Hospital1112020
51 organizations
Page 1 / 3