Eucalyptol
Trade name: listerine
Small moleculeexperimental
Listerine is an American brand of antiseptic mouthwash that is promoted with the slogan "Kills germs that cause bad breath". Named after Joseph Lister, who pioneered antiseptic surgery at the Glasgow Royal Infirmary in United Kingdom, Listerine was developed in 1879 by Joseph Lawrence, a chemist in St. Louis, Missouri. — Wikipedia
Clinical trial activity
10 trials · 11 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
2
Phase 3
0
Phase 4
4
Earliest trial started Jun 1, 2009 (NCT00885599)
Timeline
Indications
Approved for
Mechanism of action
NFKB1 inhibitor
PPARG inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
Cc1ccc(C(C)C)c(O)c1- Mol. weight
- 150.22 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaListerine ↗
- ChEMBLCHEMBL29411 ↗
Also known as
- eftab
- gppe mthwsh tab
- listerine
- listerine
- listerine
- sotol
- tellodont
- tellora
- valda
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07119840 | N/A | Aug 1, 2025 | Khyber Medical University Peshawar, Khyber Medical University Peshawer, Saidu College of Dentistry |
| NCT04827966 | N/A | Dec 1, 2021 | Government of Bahrain |
| NCT05121909 | Phase 4 | Nov 15, 2021 | All Sum Research Center Ltd., Johnson and Johnson |
| NCT04966507 | Phase 2 | Aug 31, 2021 | National Institute of Allergy and Infectious Diseases (NIAID), University of California, Los Angeles |
| NCT05120141 | Phase 4 | Mar 29, 2021 | All Sum Research Center Ltd., Johnson and Johnson |
| NCT04750005 | Phase 4 | Oct 23, 2020 | Johnson and Johnson, Salus Research |
| NCT04449952 | Phase 4 | Dec 2, 2019 | Johnson and Johnson, Salus Research |
| NCT04921371 | Phase 1 | Oct 8, 2019 | Johnson and Johnson, Salus Research |
| NCT01637948 | Phase 1 | Oct 1, 2010 | The University of Hong Kong |
| NCT00885599 | Phase 1/Phase 2 (Phase 2) | Jun 1, 2009 | Hebrew University |
Showing 10 of 10 trials
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Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Johnson and Johnson | For profit | 5 | 5 | 2 | 2019 |
| Salus Research | For profit | 3 | 0 | 2 | 2019 |
| All Sum Research Center Ltd. | For profit | 2 | 0 | 1 | 2021 |
| Government of Bahrain | Government | 1 | 1 | 1 | 2021 |
| Hebrew University | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Khyber Medical University Peshawar | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Khyber Medical University Peshawer | Academic/Hospital | 1 | 0 | 1 | 2025 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 0 | 1 | 2021 |
| Saidu College of Dentistry | Academic/Hospital | 1 | 0 | 1 | 2025 |
| The University of Hong Kong | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of California, Los Angeles | Academic/Hospital | 1 | 1 | 1 | 2021 |
11 organizations
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