collagen
Animal productexperimental
Gelatin or gelatine is a translucent, colorless, flavorless food ingredient, commonly derived from collagen taken from animal body parts. It is brittle when dry and rubbery when moist. It may also be referred to as hydrolyzed collagen, collagen hydrolysate, gelatine hydrolysate, hydrolyzed gelatine, and collagen peptides after it has undergone hydrolysis. It is commonly used as a gelling agent in food, beverages, medications, drug or vitamin capsules, photographic films, papers and cosmetics. — Wikipedia
Clinical trial activity
166 trials · 185 clinical orgs · 0 marketing orgs
Phase 1
27
Phase 2
35
Phase 3
15
Phase 4
17
Earliest trial started Jul 1, 1999 (NCT00000401)
Timeline
Indications
Approved for
Studied for
- Abscess · Phase 3
- Aging · Phase 1
- Alveolar Bone Loss · Phase 4
- Alzheimer Disease · Phase 3
- Anemia · Phase 1/Phase 2
- Arthritis, Rheumatoid · Phase 2
- Arthroplasty, Replacement · Phase 3
- Bone Diseases · Phase 3
- Bone Resorption · Phase 3
- Brain Injuries · Phase 1
- Breast Neoplasms · Phase 1
- Cardiomyopathies · Phase 1/Phase 2
- Chronic Periodontitis · Phase 2
- Collagen · Phase 4
- Connective Tissue Diseases · Phase 2
- COVID-19 · Phase 2/Phase 3
- Cytokine Release Syndrome · Phase 1
- Dental Implants · Phase 4
- Dental Pulp Exposure · Early Phase 1
- Diabetes Complications · Phase 4
- Diabetes Mellitus · Phase 4
- Diabetes Mellitus, Type 1 · Phase 1
- Diabetes Mellitus, Type 2 · Phase 1
- Diabetic Foot · Phase 2
- Dry Eye Syndromes · Phase 2
- Erectile Dysfunction · Phase 1
- Eye Diseases · Phase 2
- Fasciitis, Plantar · Phase 4
- Fibrosis · Phase 1/Phase 2
- Foot Ulcer · Phase 4
- Gingival Recession · Phase 4
- Glaucoma · Phase 4
- Glaucoma, Angle-Closure · Phase 3
- Glaucoma, Neovascular · Phase 3
- Glaucoma, Open-Angle · Phase 4
- Hemostatic Techniques · Phase 2
- Hernia, Inguinal · Phase 2
- Herniorrhaphy · Phase 3
- Hyperpigmentation · Phase 2
- Idiopathic Pulmonary Fibrosis · Phase 1
- Infertility, Female · Phase 1/Phase 2
- Inflammation · Phase 4
- Knee Injuries · Phase 3
- Liver Cirrhosis · Phase 1/Phase 2
- Liver Neoplasms · Phase 2
- Maxillary Sinus · Phase 3
- Muscle Hypotonia · Phase 1
- Nasal Septal Perforation · Phase 1/Phase 2
- Nephrectomy · Phase 2
- Nerve Fibers · Phase 3
- Orthodontic Extrusion · Phase 2
- Osteoarthritis · Phase 4
- Osteoarthritis, Knee · Phase 3
- Osteoporosis · Phase 1
- Periodontal Diseases · Early Phase 1
- Periodontitis · Phase 1/Phase 2
- Postoperative Pain · Phase 3
- Pregnancy · Phase 4
- Prostheses and Implants · Phase 1/Phase 2
- Pulmonary Fibrosis · Phase 1
- Rectal Fistula · Phase 3
- Rehabilitation · Phase 4
- Rotator Cuff Injuries · Phase 4
- Scleroderma, Systemic · Phase 2
- Spinal Cord Injuries · Phase 1
- Temporomandibular Joint Disorders · Early Phase 1
- Thalassemia · Phase 4
- Tooth Abnormalities · Phase 4
- Tooth Socket · Phase 4
- Trabeculectomy · Phase 3
- Uveitis · Phase 3
- Vocal Cord Dysfunction · Phase 1
- Whey Proteins · Phase 4
- Wounds and Injuries · Phase 4
Mechanism of action
- Unspecified targetTissue restoration
tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGelatin ↗
- NCATS0127KU7397 ↗
- WikipediaFleece ↗
- WikipediaCollagen ↗
Also known as
- activated collagen
- bio-oss
- bovine type i collagen
- bovine type ii collagen
- ci
- cii
- colla corii asini
- colla corii asini
- collagen
- collagen
- collagen hydrolysate
- ejiao
- ejiao
- e-jiao
- fleece
- hydrolyzed collagen
- iw001
- type i bovine collagen
- type-ii collagen
- xaracoll
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07229014 | N/A | Dec 31, 2025 | ROUSSELOT SAS, University of London |
| NCT07149064 | N/A | Nov 30, 2025 | KGK Science Inc., ROUSSELOT SAS |
| NCT07119645 | N/A | Oct 19, 2025 | Hofseth Biocare ASA |
| NCT07195396 | N/A | Sep 29, 2025 | BioTeSys GmbH, ROUSSELOT SAS |
| NCT07062198 | Phase 3 | Sep 12, 2025 | ScandiBio Therapeutics AB |
| NCT07174323 | N/A | Sep 8, 2025 | Inquis Clinical Research |
| NCT06935747 | Phase 4 | Jul 31, 2025 | Universidad de Murcia, University of Santiago de Compostela |
| NCT07148908 | N/A | Jul 1, 2025 | Lesaffre International, University of Toronto |
| NCT06937801 | N/A | May 8, 2025 | Nutrasource Diagnostics, ROUSSELOT SAS |
| NCT06831214 | N/A | Feb 1, 2025 | Cairo University |
| NCT06755892 | N/A | Jan 27, 2025 | Higher School of Applied Sciences (VIST), Slovenian Research Agency, Tosla d.o.o. |
| NCT06900660 | N/A | Jan 13, 2025 | Chia Nan University of Pharmacy and Science, Simply Plus Co., Ltd. |
| NCT06725082 | Phase 1 | Dec 1, 2024 | Peking University |
| NCT06689761 | N/A | Nov 13, 2024 | CRI Collagen Research Institute GmbH, University of Vienna |
| NCT06553222 | Phase 3 | Nov 4, 2024 | Al Azhar University |
| NCT06771388 | N/A | Nov 1, 2024 | Chia Nan University of Pharmacy and Science, TCI Co., Ltd. |
| NCT07011225 | Phase 4 | Aug 26, 2024 | Federal University of Sao Paulo |
| NCT06603194 | N/A | Aug 26, 2024 | Ancient Brave, Princeton Consumer Research Inc. |
| NCT06633640 | Early Phase 1 (Phase 1) | Aug 1, 2024 | Cairo University |
| NCT06465407 | N/A | Jul 1, 2024 | University of Central Florida |
Showing 20 of 166 trials
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Organizations
Research & Development (185)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| ROUSSELOT SAS | For profit | 10 | 7 | 2 | 2010 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 9 | 7 | 2 | 2015 |
| Chia Nan University of Pharmacy and Science | Academic/Hospital | 7 | 1 | 1 | 2020 |
| Innocoll | For profit | 7 | 7 | 2 | 2008 |
| Nanjing University | Academic/Hospital | 6 | 2 | 2 | 2015 |
| TCI Co., Ltd. | For profit | 6 | 6 | 1 | 2020 |
| Premier Research Group | For profit | 5 | 0 | 2 | 2008 |
| BioTeSys GmbH | For profit | 4 | 0 | 1 | 2019 |
| Cairo University | Academic/Hospital | 4 | 4 | 2 | 2013 |
| Guangzhou University | Academic/Hospital | 4 | 3 | 3 | 2015 |
| Higher School of Applied Sciences (VIST) | Academic/Hospital | 4 | 4 | 1 | 2018 |
| Instituto Mexicano del Seguro Social | Government | 4 | 3 | 3 | 2018 |
| McMaster University | Academic/Hospital | 4 | 4 | 1 | 2016 |
| Pro Top & Mediking Company Limited | For profit | 4 | 4 | 2 | 2007 |
| University of California, Davis | Academic/Hospital | 4 | 3 | 1 | 2017 |
| Aeon Astron Europe B.V. | For profit | 3 | 2 | 3 | 2009 |
| Maastricht University | Academic/Hospital | 3 | 3 | 1 | 2021 |
| Slovenian Research Agency | Academic/Hospital | 3 | 0 | 1 | 2021 |
| Tosla d.o.o. | For profit | 3 | 0 | 1 | 2021 |
| University of Toronto | Academic/Hospital | 3 | 3 | 1 | 2023 |
185 organizations
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