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sulfacetamide

Trade name: sultrin

Small moleculeapproved

Approved

Sep 12, 1945

Sulfacetamide is a synthetic sulfonamide antibiotic, which exerts its effect through inhibition of bacterial dihydrofolate synthetase, an enzyme responsible for the conversion of p-aminobenzoic acid into folic acid in bacterias. The topical formulation of the drug is prescribed for the treatment of acne vulgaris and the ophtalmic formulation is used in patients with eye infections. — NCATS

Clinical trial activity

1 trials · 1 clinical orgs · 28 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
1

Earliest trial started Oct 1, 2014 (NCT02256969)

Timeline

1940s

  1. Sep 12, 1945

    McNeil — Earliest FDA Approval

  2. Sep 12, 1945

    Johnson and Johnson — NDA Secondary Org

  3. Sep 12, 1945

    McNeil — NDA Organization

  4. Jul 21, 1946

    Schering — NDA Secondary Org

1960s

  1. Sep 18, 1961

    Allergan — Marketing Organization

  2. Sep 18, 1961

    Allergan — NDA Secondary Org

  3. Jun 23, 1965

    Schering — Marketing Organization

1970s

  1. Sep 29, 1970

    Optopics — Marketing Organization

  2. May 5, 1971

    Alcon — Marketing Organization

  3. Dec 22, 1971

    Perrigo — Marketing Organization

  4. Dec 22, 1971

    Padagis Us — Marketing Organization

  5. Aug 24, 1972

    Miza Pharmaceuticals — Marketing Organization

  6. Nov 1, 1974

    Johnson and Johnson — Marketing Organization

1980s

  1. Jul 21, 1981

    Nestle — Marketing Organization

  2. Jul 23, 1982

    Savage Labs — Marketing Organization

  3. Dec 22, 1982

    Pharmafair — Marketing Organization

  4. Dec 28, 1982

    Bausch & Lomb — Marketing Organization

  5. Jul 29, 1983

    Akorn, Inc. — Marketing Organization

  6. Oct 5, 1984

    Novartis — Marketing Organization

  7. Jun 9, 1986

    Cosette — Marketing Organization

  8. Jun 9, 1986

    ACP Nimble — Marketing Organization

  9. Dec 3, 1986

    SmithKline Beckman — Marketing Organization

  10. Aug 26, 1988

    Novartis — NDA Secondary Org

  11. Oct 18, 1988

    Sandoz — Marketing Organization

  12. Sep 29, 1989

    SmithKline Beecham — NDA Secondary Org

1990s

  1. May 27, 1993

    Genus Oncology, LLC — Marketing Organization

  2. Dec 23, 1996

    Bausch Health Companies — NDA Secondary Org

  3. Dec 23, 1996

    Bausch Health Companies — Marketing Organization

  4. May 25, 1999

    Epic Pharma Llc — Marketing Organization

  5. May 25, 1999

    Sciegen Pharmaceticals — Marketing Organization

2000s

  1. Nov 17, 2006

    Fougera — Marketing Organization

  2. May 20, 2009

    Taro Pharmaceuticals — Marketing Organization

Indications

Approved for

Studied for

Mechanism of action

Combination products

Approval history

  • approvedSep 12, 1945

Chemistry & pharmacology

Loading structure…

SMILES

CC(=O)[N-]S(=O)(=O)c1ccc(N)cc1.O.[Na+]
Mol. weight
254.24 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No
Delivery
Topical
Availability
Prescription Only

Oral

No

Parenteral

No

Topical

Yes

Sources

Also known as

  • acetosulfamin
  • acetosulfamine
  • acetosulfamine
  • acetosulfamine
  • albucid
  • albucid
  • albucid
  • bleph
  • bleph
  • bleph-10
  • bleph-10
  • bleph-30
  • bleph-30
  • blephamide
  • blephamide
  • cetamide
  • cetamide
  • fml-s
  • fml-s
  • formosulfacetamide
  • isopto cetamide
  • isopto cetamide
  • klaron
  • klaron
  • n(1)-acetyl-4-aminophenylsulfonamide
  • n(1)-acetyl-4-aminophenylsulfonamide
  • n(1)-acetylsulfanilamide
  • n(1)-acetylsulfanilamide
  • n-acetyl-4-aminobenzenesulfonamide
  • n-acetyl-4-aminobenzenesulfonamide
  • n-acetylsulfanilamide
  • n-acetylsulfanilamide
  • n-acetylsulfanilamide
  • n'-acetylsulfanilamide
  • n'-acetylsulfanilamide
  • novacet
  • n-(p-aminobenzenesulfonyl)acetamide
  • n-(p-aminobenzenesulfonyl)acetamide
  • n-((p-aminophenyl)sulfonyl)acetamide
  • n-((p-aminophenyl)sulfonyl)acetamide
  • n-[(p-aminophenyl)sulfonyl]acetamide
  • n-[(p-aminophenyl)sulfonyl]acetamide
  • n-sulfanilylacetamide
  • n-sulfanilylacetamide
  • n-sulfanilylacetamide
  • n-sulphanilylacetamide
  • n-sulphanilylacetamide
  • ocusol
  • ocusulf
  • ocusulf
  • ocusulf-10
  • ocusulf-10
  • ocusulf-30
  • ocusulf-30
  • p-aminobenzenesulfonacetamide
  • p-aminobenzenesulfonacetamide
  • p-aminobenzenesulfonoacetamide
  • p-aminobenzenesulfonoacetamide
  • sodium sulamyd
  • sodium sulamyd
  • sodium sulfacetamide
  • sodium sulfacetamide
  • sulf-10
  • sulf-10
  • sulf-15
  • sulf-15
  • sulfacel
  • sulfacel
  • sulfacel-15
  • sulfacel-15
  • sulfacet
  • sulfacetamid
  • sulfacetamid
  • sulfacetamida
  • sulfacetamida
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacetamide
  • sulfacétamide
  • sulfacétamide
  • sulfacetamide sodic hydrate
  • sulfacetamide sodium
  • sulfacetamide sodium
  • sulfacetamide sodium
  • sulfacetamide sodium
  • sulfacetamide (triple sulfa)
  • sulfacetamide (triple sulfa)
  • sulfacetamidum
  • sulfacetamidum
  • sulfacetimide
  • sulfair 10
  • sulfair 10
  • sulfair-15
  • sulfair-15
  • sulfair forte
  • sulfair forte
  • sulfanilazetamid
  • sulfanilazetamid
  • sulphacetamide
  • sulphacetamide
  • sulphacetamide
  • sulphacetamide
  • sulphacetamidum
  • sulphacetamidum
  • sulster
  • sulster
  • sulten-10
  • sulten-10
  • sultrin
  • sultrin

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02256969Phase 4Oct 1, 2014Harvard University
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (1)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Harvard UniversityAcademic/Hospital1112014
1 organizations
Page 1 / 1

Marketing (36)

OrganizationOrg typeRelationshipDate
ACP NimbleFor profitMKTGJun 9, 1986
Akorn, Inc.For profitMKTGJul 29, 1983
AlconFor profitMKTGMay 5, 1971
AlconFor profitSYNMay 5, 1987
AllerganFor profitMKTGSep 18, 1961
AllerganFor profitNDA2Sep 18, 1961
AlpharmaFor profitMKTG—
Bausch & LombFor profitMKTGDec 28, 1982
Bausch Health CompaniesFor profitNDA2Dec 23, 1996
Bausch Health CompaniesFor profitMKTGDec 23, 1996
CosetteFor profitMKTGJun 9, 1986
Epic Pharma LlcFor profitMKTGMay 25, 1999
FougeraFor profitMKTGNov 17, 2006
Genus Oncology, LLCFor profitMKTGMay 27, 1993
Johnson and JohnsonFor profitNDA2Sep 12, 1945
Johnson and JohnsonFor profitMKTGNov 1, 1974
McNeilFor profitNDASep 12, 1945
Miza PharmaceuticalsFor profitMKTGAug 24, 1972
NestleFor profitMKTGJul 21, 1981
NovartisFor profitMKTGOct 5, 1984
NovartisFor profitNDA2Aug 26, 1988
OptopicsAcademic/HospitalMKTGSep 29, 1970
Padagis UsFor profitMKTGDec 22, 1971
PerrigoFor profitSYNNov 15, 1982
PerrigoFor profitMKTGDec 22, 1971
PharmadermFor profitMKTG—
PharmafairFor profitMKTGDec 22, 1982
SandozFor profitMKTGOct 18, 1988
SandozFor profitSYNOct 18, 1988
Savage LabsFor profitMKTGJul 23, 1982
ScheringFor profitMKTGJun 23, 1965
ScheringFor profitNDA2Jul 21, 1946
Sciegen PharmaceticalsFor profitMKTGMay 25, 1999
SmithKline BeckmanFor profitMKTGDec 3, 1986
SmithKline BeechamFor profitNDA2Sep 29, 1989
Taro PharmaceuticalsFor profitMKTGMay 20, 2009