CDEK
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glucose

Small moleculeapproved

Inverted sugar syrup is a syrup mixture of the monosaccharides glucose and fructose, made by splitting disaccharide sucrose. This mixture's optical rotation is opposite to that of the original sugar, which is why it is called an invert sugar. Splitting is completed through hydrolytic saccharification. — Wikipedia

Clinical trial activity

385 trials · 355 clinical orgs · 1 marketing orgs

Phase 1
44
Phase 2
52
Phase 3
24
Phase 4
37

Earliest trial started Feb 25, 1998 (NCT00001651)

Timeline

1970s

  1. Jun 1, 1970

    Baxter — First NDA Organization

  2. Jun 1, 1970

    Baxter — NDA Organization

1990s

  1. Jan 1, 1999

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 1999

    Earliest Phase 3 Sponsor(trial)

2000s

  1. Jan 1, 2004

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetSupplementation

    supplementation

Approval history

  • approved—

Chemistry & pharmacology

Loading structure…

SMILES

OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O
Mol. weight
180.16 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Parenteral
Availability
Discontinued

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • 1,3-beta-glucan
  • anhydrous glucose
  • anhydrous glucose
  • anhydrous glucose
  • beta-1,3-glucan
  • beta-1,3-glucan
  • beta-1,3-glucan
  • glucose
  • glucose
  • glucose
  • glucose
  • glucose
  • glucose
  • glucose
  • glucose-40
  • glucose-40
  • glucose anhydrous
  • glucose, anhydrous
  • glucose, anhydrous
  • glucose, liquid
  • insta-glucose
  • invertose
  • invert sugar
  • invert sugar
  • invert sugar
  • invert sugar
  • invert sugar
  • sugar, invert
  • sugar, invert

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06955130N/AJul 1, 2026Rutgers University
NCT07311330Phase 2Jan 31, 2026Beijing Inno Medicine Co., Ltd.
NCT06930976N/AOct 1, 2025Vanderbilt University
NCT07008456Phase 2Sep 12, 2025Aphaia Pharma US LLC
NCT07131904N/AAug 12, 2025Bern University of Applied Sciences
NCT07013916N/AJun 30, 2025University of London, University of Surrey
NCT06799715N/AFeb 6, 2025St. Claraspital Basel, University of Basel
NCT06714552N/ADec 31, 2024University of Aberdeen, Yakult Honsha Co., LTD
NCT06643351N/ADec 31, 2024University of Pittsburgh
NCT06558422Phase 1Dec 1, 2024Columbia University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of California, Berkeley
NCT06671756N/ANov 7, 2024Baylor University
NCT06609356Early Phase 1 (Phase 1)Nov 1, 2024Vanderbilt University
NCT06638190N/AOct 21, 2024Centro de Edafología y Biología Aplicada del Segura, Universidad Católica San Antonio de Murcia
NCT06329544N/AOct 8, 2024Icahn School of Medicine at Mount Sinai, Metabolic Solutions Inc., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06624956Phase 4Oct 1, 2024University of Washington
NCT06424106N/AOct 1, 2024Mayo Clinic
NCT06597201Phase 4Sep 9, 2024Government of China
NCT06469970Phase 4Sep 1, 2024University of Lorraine
NCT06710743N/AJul 1, 2024PepsiCo
NCT06325644N/AJun 1, 2024Ohio State University
Showing 20 of 385 trials
Page 1 / 20

Organizations

Research & Development (355)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Agricultural University of AthensAcademic/Hospital151512014
University of TorontoAcademic/Hospital131332010
University of BernAcademic/Hospital111022006
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Government8122006
University of CopenhagenAcademic/Hospital8632009
University of ViennaAcademic/Hospital7541999
Vanderbilt UniversityAcademic/Hospital7732002
Maastricht UniversityAcademic/Hospital6412009
National University of SingaporeAcademic/Hospital6612016
Ohio State UniversityAcademic/Hospital6612015
Aarhus UniversityAcademic/Hospital5522010
Baylor UniversityAcademic/Hospital5221999
Harvard UniversityAcademic/Hospital5232006
MerckFor profit5412007
University of LyonAcademic/Hospital5422009
University of Sao PauloAcademic/Hospital5432006
Aphaia Pharma US LLCFor profit4422019
Canadian Institutes of Health Research (CIHR)Academic/Hospital4012010
Columbia UniversityAcademic/Hospital4412023
Rutgers UniversityAcademic/Hospital4412016
355 organizations
Page 1 / 18

Marketing (1)

OrganizationOrg typeRelationshipDate
BaxterFor profitNDAJun 1, 1970