sodium monododecyl sulfate

Small moleculeexperimental

Sodium dodecyl sulfate (SDS) or sodium lauryl sulfate (SLS), sometimes written sodium laurilsulfate, is an organic compound with the formula CH3(CH2)11OSO3Na and structure H3C−(CH2)11−O−S(=O)2−O−Na+. It is an anionic surfactant used in many cleaning and hygiene products. This compound is the sodium salt of the 12-carbon organosulfate. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties that make it useful as a detergent. SDS is also component of mixtures produced from inexpensive coconut and palm oils. SDS is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations. — Wikipedia

Clinical trial activity

32 trials · 27 clinical orgs · 0 marketing orgs

Phase 1
21
Phase 2
2
Phase 3
1
Phase 4
6

Earliest trial started May 1, 2005 (NCT00967174)

Timeline

2000s

  1. Jan 1, 2005

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2006

    Earliest Phase 2 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • Unspecified targetSurfactant

    surfactant

Chemistry & pharmacology

Loading structure…

SMILES

CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]
Mol. weight
288.38 g/mol
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • e487
  • e487
  • laurylsiran sodny
  • laurylsiran sodny
  • nads
  • nads
  • nads
  • natrium laurylsulfuricum
  • natrium laurylsulfuricum
  • sds
  • sds
  • sls
  • sls
  • sodium dodecylsulfate
  • sodium dodecylsulfate
  • sodium dodecyl sulfate
  • sodium dodecyl sulfate
  • sodium dodecyl sulphate
  • sodium dodecyl sulphate
  • sodium laurilsulfate
  • sodium laurilsulfate
  • sodium lauryl sulfate
  • sodium lauryl sulfate
  • sodium lauryl sulfate
  • sodium lauryl sulfate
  • sodium lauryl sulfate
  • sodium lauryl sulfate
  • sodium lauryl sulphate
  • sodium lauryl sulphate
  • sodium lauryl sulphate
  • sodium monododecyl sulfate
  • sodium monododecyl sulfate
  • sodium monododecyl sulfate
  • sodium monododecyl sulfate
  • sodium monododecyl sulfate

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02589405Phase 4Aug 1, 2015Galderma, Proinnovera GmbH
NCT02256930Phase 1Sep 1, 2014Maruho Co., Ltd.
NCT02227069Phase 1Sep 1, 2014Maruho Co., Ltd.
NCT02218463N/ASep 1, 2014University of Kansas, University of Missouri, University of Missouri, Kansas City
NCT02249104Phase 4Aug 1, 2014Galderma, Pflugerville Dermatology Clinical Research
NCT02198963Phase 1Jul 1, 2014Bio-Science Laboratories, Pulmatrix Inc.
NCT02160574Phase 1Jun 1, 2014Bio-Science Laboratories, Zurex Pharma, Inc.
NCT02169154Phase 1Jun 1, 2014GlaxoSmithKline
NCT02168478Phase 4Jun 1, 2014Consumer Product Testing Corporation, Medimetriks
NCT02117752Phase 1Apr 1, 2014Allergan
NCT02061813Phase 1Jan 1, 2014Hatchtech Pty Ltd, TKL Research
NCT02062073Phase 1Jan 1, 2014Accelovance, Hatchtech Pty Ltd, TKL Research
NCT01984775Phase 1Oct 30, 2013GlaxoSmithKline, Stiefel Laboratories
NCT01821274Phase 1Mar 1, 2013Ventrus Biosciences, Inc
NCT01816529Phase 1Mar 1, 2013Ventrus Biosciences, Inc
NCT01771822Phase 1Jan 1, 2013Pfizer
NCT01787448Phase 1Jan 1, 2013Pfizer
NCT01638117Phase 1Apr 1, 2012Amorepacific Corporation, Seoul National University
NCT01762982N/AFeb 1, 2012GlaxoSmithKline
NCT01430312Phase 1Sep 1, 2011Bayer
Showing 20 of 32 trials
Page 1 / 2

Organizations

Research & Development (27)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
GaldermaFor profit5422006
GlaxoSmithKlineFor profit5232006
PfizerFor profit5512007
BayerFor profit2212009
Bio-Science LaboratoriesFor profit2012014
Hatchtech Pty LtdFor profit2212014
Maruho Co., Ltd.For profit2212014
Oregon Health and Science UniversityAcademic/Hospital2222006
Stiefel LaboratoriesFor profit2212010
TKL ResearchFor profit2012014
Ventrus Biosciences, IncFor profit2212013
Wake Forest UniversityAcademic/Hospital2222006
AccelovanceFor profit1012014
AllerganFor profit1112014
Amorepacific CorporationFor profit1112012
Consumer Product Testing CorporationAcademic/Hospital1012014
McNeilFor profit1112005
MedimetriksFor profit1112014
National Eczema AssociationAcademic/Hospital1012006
Pflugerville Dermatology Clinical ResearchAcademic/Hospital1012014
27 organizations
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