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Dental Caries
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
Subtype terms (1)
More specific conditions that are subtypes of Dental Caries in the MeSH hierarchy.
- Root Caries
4 drugs (3 approved, 1 experimental)
Drugs by status
Approved for this indication (11)
Phase 4 trials (25)
- vitamin d3
- bifidobacterium animalis
- cetylpyridinium chloride
- ketamine
- formocresol
- calcium hydroxide
- vitis vinifera
- meperidine
- potassium iodide
- polyacrylamide
- acetylsalicylic acid
- buprenorphine
- autologous microbiome
- lactobacillus brevis
- dexmedetomidine
- silicon dioxide
- thymol
- midazolam
- moringa
- sodium chloride
- chlorhexidine
- hydroxyzine
- ergocalciferol
- lactobacillus reuteri
- casein phosphopeptide amorphous calcium phosphate
Phase 3 trials (25)
- nitrous oxide
- stearyl trihydroxyethyl propylenediamine dihydrofluoride
- chitosan
- cinnamon
- erythritol
- ginger
- iodine
- mepivacaine
- mineral trioxide
- epinephrine
- immune globulin (human)
- silver nitrate
- sorbitol
- articaine
- acacia
- sodium perchlorate
- titanium
- oxygen
- licorice
- guava leaves extract
- water
- lactobacillus casei
- glutaraldehyde
- Gum Arabic
- lactobacillus delbrueckii
Phase 2 trials (14)
Phase 1 trials (14)
Other trials (52)
- melatonin
- sodium citrate
- colloidal silver
- sucrose
- petrolatum, white
- benzocaine
- coconut oil
- egg
- ferric sulfate
- glycerine magnesium sulphate
- ozone
- ketone
- lithium
- hydroxyapatite silica
- miswak
- human milk
- cow milk
- pomegranate
- lidocaine
- methylene blue
- resin modified glass ionomer
- dentin
- calcium silicate
- pelargonium
- vancomycin
- apple
- curcumin
- moringa oleifera
- sodium phytate
- zinc dichloride
- +22 more
Organizations
Organization Involved with Phase 4 Indications (29)
- Gaba International AG
- GlaxoSmithKline
- Colgate Palmolive
- Chr Hansen
- Ain Shams University
- Cairo University
- University of London
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- University of Washington
- Universidad Iberoamericana
- University of Glasgow
- University of Milan
- University of Oslo
- University of Pernambuco
- Aga Khan University
- University of California, San Francisco
- University of Turku
- Federal University of Paraiba
- Hebrew University
- NHS Scotland
- University of Sassari
- University of Sao Paulo
- University of Gothenburg
- Federal University of Goias
- University of Paris
- Humboldt University
- South-Eastern Norway Regional Health Authority
- Plastone Oy
- King Abdul-Aziz University
Organization Involved with Phase 3 Indications (35)
- Medical Research Council
- National Institute of Dental and Craniofacial Research (NIDCR)
- Alexandria University
- British University In Egypt
- Federal University of Pelotas
- New York University
- Sharda University
- Texas A&M University
- Tufts University
- Universidad El Bosque, Bogotá
- University of Iowa
- University of Michigan
- University of Tartu
- University of Toronto
- University of California, Los Angeles
- University of California, San Diego
- Zhejiang University
- University of Baghdad
- Umea University
- Advantage Dental
- Karolinska Institute
- The University of Hong Kong
- Sun Yat-Sen University
- The Swedish Research Council
- Canadian Institutes of Health Research (CIHR)
- Ekhagastiftelsen
- Hangzhou Occupational Disease Prevention Hospital
- Oskar Foundation
- The Yakima Valley Farm Workers Clinic
- State of Washington
- +5 more
Organization Involved with Phase 2 Indications (17)
- National Institutes of Health (NIH)
- Indiana University
- Jean Brown Research
- Peoples University, Bhanpur, Bhopal
- Thammasat University
- University of Peradeniya
- Virginia Commonwealth University
- Advantage Silver Dental Arrest, LLC
- Vantage Data Designs, Inc.
- E Squared Trials and Registries, Inc.
- Agility Clinical, Inc.
- Synteract, Inc.
- C3J Therapeutics
- The University of Texas, Dallas
- Pharos University in Alexandria
- Delta Dental Foundation
- Water Pik, Inc.
Organization Involved with Phase 1 Indications (9)
Organization Involved with Other Experimental Indications (25)
- Baylor University
- Case Western Reserve University
- NHS Fife
- Riyadh Colleges of Dentistry and Pharmacy
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
- University of Maryland
- University of Nebraska
- University of Chile
- University of Copenhagen
- Misr International University
- Fluminense Federal University
- Jordan University
- Damascus University
- National Taiwan University
- Al Azhar University
- The Oxford Dental College, Bangalore, India
- NHS Forth Valley
- Federal University of Ceara
- Indira Ghandhi Institute of Medical Science
- University of Illinois at Chicago
- Health Resources and Services Administration (HRSA)
- Izmir Katip Celebi University
- A.T. Still University of Health Sciences
- Dr. Kurt Wolff GmbH & Co. KG
- Government of Jordan