mineral trioxide
Small moleculeexperimental
Clinical trial activity
25 trials · 25 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
6
Phase 3
5
Phase 4
5
Earliest trial started May 1, 2007 (NCT00472173)
Timeline
Indications
Approved for
Studied for
- Colorectal Neoplasms · Phase 4
- Dental Caries · Phase 2/Phase 3
- Dental Prosthesis · Phase 2/Phase 3
- Dental Pulp · Phase 4
- Dental Pulp Diseases · Phase 4
- Dental Pulp Exposure · Phase 2/Phase 3
- Dental Pulp Necrosis · Phase 3
- Pulpitis · Phase 4
- Pulpotomy · Phase 4
- Tooth · Phase 2/Phase 3
- Tooth Diseases · Phase 4
- Tooth, Nonvital · Phase 2
Mechanism of action
- Unspecified targetUnclear
Unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- aggregate proroot
- gray mineral trioxide aggregate
- mineral trioxide
- mineral trioxide aggregate
- mineral trioxide aggregate
- mta cement
- mta-fillapex
- mt aggregate
- orthomta
- proroot (aggregate)
- retromta
- theracal
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06435065 | Phase 4 | Apr 1, 2024 | Maharishi Markandeshwar University |
| NCT05811403 | N/A | Jul 1, 2023 | Cairo University |
| NCT06372561 | N/A | May 20, 2023 | Suez Canal University |
| NCT06402032 | N/A | Sep 1, 2022 | Cairo University |
| NCT06116695 | Phase 1/Phase 2 (Phase 2) | Jan 18, 2022 | Tanta University |
| NCT07120321 | N/A | Jan 1, 2022 | Inonu University |
| NCT05530954 | Phase 3 | Jan 1, 2022 | Mansoura University |
| NCT04863222 | Phase 4 | Nov 12, 2021 | Geisinger Clinic |
| NCT04903808 | Phase 2/Phase 3 (Phase 3) | Sep 30, 2021 | Cairo University |
| NCT04795830 | Phase 4 | Aug 1, 2021 | Ain Shams University |
| NCT04770792 | N/A | Apr 6, 2019 | King Abdulaziz University, King Abdul-Aziz University |
| NCT03580135 | Phase 2 | Aug 1, 2018 | Cairo University |
| NCT02887456 | Phase 2 | Sep 1, 2016 | University of Sao Paulo |
| NCT02783911 | N/A | Apr 1, 2016 | Loma Linda University |
| NCT02298504 | Phase 4 | Nov 1, 2015 | University of Maryland |
| NCT02805101 | N/A | Jan 1, 2015 | Damascus University |
| NCT02803528 | N/A | Jan 1, 2015 | Damascus University |
| NCT02492841 | Phase 2/Phase 3 (Phase 3) | Apr 1, 2014 | Universidad de los Andes |
| NCT02286648 | Phase 4 | Feb 1, 2014 | Mashhad University of Medical Sciences |
| NCT01420718 | Phase 2/Phase 3 (Phase 3) | Jun 1, 2011 | Azad University |
Showing 20 of 25 trials
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Organizations
Research & Development (25)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cairo University | Academic/Hospital | 4 | 4 | 3 | 2018 |
| Azad University | Academic/Hospital | 2 | 2 | 2 | 2010 |
| Damascus University | Academic/Hospital | 2 | 2 | 1 | 2015 |
| Ain Shams University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Geisinger Clinic | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Inonu University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| King Abdulaziz University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| King Abdul-Aziz University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Loma Linda University | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Maharishi Markandeshwar University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Mansoura University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Mashhad University of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2014 |
| National Institute of Dental and Craniofacial Research (NIDCR) | Government | 1 | 0 | 1 | 2009 |
| National Taiwan University | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Oregon Health and Science University | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Suez Canal University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Tanta University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Universidad de los Andes | Academic/Hospital | 1 | 1 | 1 | 2014 |
| University of Maryland | Academic/Hospital | 1 | 1 | 1 | 2015 |
| University of Michigan | Academic/Hospital | 1 | 0 | 1 | 2009 |
25 organizations
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