sodium fluoride
Small moleculeexperimental
Clinical trial activity
40 trials · 32 clinical orgs · 0 marketing orgs
Phase 1
7
Phase 2
10
Phase 3
9
Phase 4
6
Earliest trial started Mar 31, 2012 (NCT02585882)
Timeline
Indications
Approved for
Studied for
- Acne Vulgaris · Phase 3
- Child Behavior · Phase 4
- Dental Caries · Phase 4
- Dental Plaque · Phase 3
- Dentin Sensitivity · Phase 3
- Dermatology · Phase 4
- Fluorides · Phase 1
- Gingival Diseases · Phase 4
- Gingivitis · Phase 4
- Hydroxyapatites · Phase 1
- Hypersensitivity · Phase 3
- Quality of Life · Phase 4
- Tooth Bleaching · Phase 3
- Tooth Discoloration · Phase 3
- Xerostomia · Phase 3
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06966492 | Phase 4 | Oct 31, 2025 | Colgate Palmolive, University of Texas at Houston |
| NCT06986551 | N/A | Sep 30, 2025 | Cairo University |
| NCT07169188 | N/A | Sep 9, 2025 | Healeon Medical Inc |
| NCT06660069 | N/A | Nov 18, 2024 | Healeon Medical Inc |
| NCT06486974 | Phase 3 | Sep 23, 2024 | Colgate Palmolive |
| NCT06602765 | N/A | Sep 5, 2024 | Bahria University |
| NCT06708481 | Early Phase 1 (Phase 1) | Aug 30, 2024 | Al Azhar University, October 6 University |
| NCT06365047 | Phase 3 | Aug 21, 2024 | Colgate Palmolive, Tufts University |
| NCT06493500 | Phase 1 | Jul 31, 2024 | Cairo University |
| NCT06358066 | Phase 1 | Jun 6, 2024 | Tanta University |
| NCT06048809 | N/A | Jun 1, 2024 | Healeon Medical Inc |
| NCT06378008 | N/A | Apr 16, 2024 | Healeon Medical Inc |
| NCT06354270 | N/A | Apr 11, 2024 | Healeon Medical Inc |
| NCT06366568 | Phase 3 | Feb 19, 2024 | Colgate Palmolive |
| NCT06220045 | N/A | Feb 1, 2024 | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta |
| NCT06180707 | Phase 3 | Jan 5, 2024 | Universidade Federal do Para |
| NCT06241261 | Phase 2 | Jan 1, 2024 | The University of Hong Kong |
| NCT06048627 | Phase 3 | Jan 1, 2024 | Colgate Palmolive |
| NCT06165042 | N/A | Dec 31, 2023 | Marmara University |
| NCT06172764 | Phase 4 | Dec 12, 2023 | Dow University of Health Sciences, Duke University, University of Karachi |
Showing 20 of 40 trials
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Organizations
Research & Development (32)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Colgate Palmolive | For profit | 9 | 8 | 2 | 2018 |
| Healeon Medical Inc | For profit | 6 | 5 | 2 | 2023 |
| Cairo University | Academic/Hospital | 3 | 3 | 2 | 2023 |
| Alexandria University | Academic/Hospital | 2 | 2 | 2 | 2020 |
| Procter and Gamble | For profit | 2 | 2 | 1 | 2020 |
| Tanta University | Academic/Hospital | 2 | 2 | 2 | 2022 |
| Al Azhar University | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Bahria University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Dow University of Health Sciences | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Duke University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Indiana University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Laval University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Mansoura University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Marmara University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Misr International University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| October 6 University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Protegera, Inc. | For profit | 1 | 1 | 1 | 2023 |
| Riyadh Elm University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Salus Research | For profit | 1 | 0 | 1 | 2023 |
32 organizations
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