polyacrylamide

Small moleculeexperimental

Polyacrylamide (abbreviated as PAM or pAAM) is a polymer with the formula (-CH2CHCONH2-). It has a linear-chain structure. PAM is highly water-absorbent, forming a soft gel when hydrated. In 2008, an estimated 750,000,000 kg were produced, mainly for water treatment and the paper and mineral industries. — Wikipedia

Clinical trial activity

9 trials · 11 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
2
Phase 3
0
Phase 4
1

Earliest trial started May 16, 2001 (NCT00016536)

Timeline

2000s

  1. Jan 1, 2001

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2016

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • Unspecified targetUnclear

    Unclear

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
Yes

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • amazingel
  • blephagel
  • carbomer
  • carbomer
  • carbomer
  • carbomer
  • carbomer 910
  • carbopol
  • carbopol
  • carbopol
  • carbopol 910
  • carbopol 910
  • carbopol 974
  • carbopol 980
  • carboxypolymethylene
  • duracryl liquid acrylamide
  • hpa-i
  • hpa-v
  • poly(aam)
  • polyacrylamide
  • polyacrylamide
  • polyacrylamide
  • polyacrylamide aes-10
  • polyacrylamide aes-5
  • polyacrylamide aes-7
  • polyacrylamide p100
  • polyacrylamides
  • rhinohide liquid acrylamide

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03997851Phase 1/Phase 2 (Phase 2)Jul 31, 2019University of Miami
NCT03005067Phase 2Dec 29, 2016GlaxoSmithKline
NCT02992392N/ADec 1, 2016Sun Yat-Sen University
NCT02832362Phase 1Jun 11, 2016GlaxoSmithKline
NCT02077231N/ASep 1, 2011Fudan University, Shanghai Jinshan Hospital
NCT01375582Early Phase 1 (Phase 1)Jun 1, 2011Bausch & Lomb, University of Rochester
NCT01563172Phase 4Jan 1, 2009GlaxoSmithKline
NCT00637962Phase 1Sep 1, 2007Bill and Melinda Gates Foundation, University of London, York University
NCT00016536Phase 1May 16, 2001National Institute of Allergy and Infectious Diseases (NIAID)
Showing 9 of 9 trials
Page 1 / 1

Organizations

Research & Development (11)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
GlaxoSmithKlineFor profit3332009
Bausch & LombFor profit1012011
Bill and Melinda Gates FoundationAcademic/Hospital1012007
Fudan UniversityAcademic/Hospital1012011
National Institute of Allergy and Infectious Diseases (NIAID)Government1112001
Shanghai Jinshan HospitalAcademic/Hospital1112011
Sun Yat-Sen UniversityAcademic/Hospital1112016
University of LondonAcademic/Hospital1112007
University of MiamiAcademic/Hospital1112019
University of RochesterAcademic/Hospital1112011
York UniversityAcademic/Hospital1012007
11 organizations
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