silicon dioxide
Small moleculeexperimental
Silicon dioxide (silica) is most commonly found in nature as quartz, as well as in various living organisms. Silicon dioxide one of the most complex and most abundant families of materials, existing both as several minerals and being produced synthetically. In food and pharmaceutical industry silica is a common additive, where it is used primarily as a flow in powdered foods, or to adsorb water in hygroscopic application. In pharmaceutical products, silica aids powder flow when tablets are formed. — NCATS
Clinical trial activity
7 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
1
Phase 4
1
Earliest trial started Sep 1, 2008 (NCT00763269)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
Unclear
Chemistry & pharmacology
Loading structure…
SMILES
O=[Si]=O- Mol. weight
- 60.0843 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSilicon dioxide ↗
- NCATSETJ7Z6XBU4 ↗
- ChEMBLCHEMBL2108563 ↗
Also known as
- cobicistat on silicon dioxide
- silica
- silica
- silica
- silica
- silica gel
- silica gel
- silica gel
- silicon dioxide
- silicon dioxide
- silicon dioxide
- silicon dioxide
- silicon dioxide
- silicon dioxide
- silicon dioxide
- silicon dioxide, colloidal
- silicon dioxide, colloidal
- silicone dioxide
- silicone dioxide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03633344 | Phase 2 | Mar 29, 2016 | Omnifarma Kiev LLC |
| NCT02683408 | N/A | Feb 1, 2016 | Primus Pharmaceuticals |
| NCT01514409 | N/A | May 1, 2011 | Northumbria University |
| NCT01571050 | Phase 1 | Jan 1, 2011 | University of Campinas |
| NCT01079910 | Phase 1 | Feb 18, 2010 | GlaxoSmithKline |
| NCT01563172 | Phase 4 | Jan 1, 2009 | GlaxoSmithKline |
| NCT00763269 | Phase 3 | Sep 1, 2008 | Colgate Palmolive, University of Puerto Rico |
Showing 7 of 7 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| GlaxoSmithKline | For profit | 2 | 2 | 2 | 2009 |
| Colgate Palmolive | For profit | 1 | 1 | 1 | 2008 |
| Northumbria University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Omnifarma Kiev LLC | For profit | 1 | 1 | 1 | 2016 |
| Primus Pharmaceuticals | For profit | 1 | 1 | 1 | 2016 |
| University of Campinas | Academic/Hospital | 1 | 1 | 1 | 2011 |
| University of Puerto Rico | Academic/Hospital | 1 | 0 | 1 | 2008 |
7 organizations
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