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curcumin

Small moleculeexperimental

Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric, a member of the ginger family, Zingiberaceae. It is sold as an herbal supplement, cosmetics ingredient, food flavoring, and food coloring. — Wikipedia

Clinical trial activity

279 trials · 266 clinical orgs · 0 marketing orgs

Phase 1
66
Phase 2
106
Phase 3
39
Phase 4
15

Earliest trial started Aug 1, 1996 (NCT00003365)

Timeline

2000s

  1. Jan 1, 2001

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2003

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2005

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetAntioxidant

    Antioxidant

Chemistry & pharmacology

Loading structure…

SMILES

COc1cc(/C=C/C(=O)/C=C(O)/C=C/c2ccc(O)c(OC)c2)ccc1O
Mol. weight
368.39 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • calcumin
  • curcuma
  • curcuma
  • curcuma
  • curcumin
  • curcumin
  • curcumin
  • curcuminoids
  • curcumol
  • curcumol
  • diferuloylmethane
  • diferuloylmethane
  • goldenseal
  • hydrastis
  • hydrastis
  • liposomal curcumin

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07251985Phase 2Feb 1, 2026University of California, Los Angeles
NCT07141368N/ASep 1, 2025Vedic Lifesciences Pvt. Ltd.
NCT06974058N/AJul 22, 2025Liaquat University of Medical & Health Sciences
NCT07063056N/AJul 18, 2025Medinutra LLC
NCT06758739Phase 3Apr 30, 2025Services Institute of Medical Sciences, Pakistan
NCT06886035Phase 4Mar 21, 2025Erzincan University
NCT06829186Phase 2Mar 15, 2025University of Guadalajara
NCT06847984N/AMar 1, 2025Cairo University
NCT07149961N/AFeb 5, 2025Diponegoro University
NCT06752655N/AJan 31, 2025Ataturk University
NCT06381076Phase 3Jan 31, 2025University of Florida
NCT06653231Early Phase 1 (Phase 1)Nov 1, 2024Cairo University, MTI University
NCT06626230Phase 1Oct 31, 2024Emory University
NCT07052890N/ASep 19, 2024The Functional Gut Clinic
NCT06531863N/ASep 1, 2024Auburn University
NCT06478290N/AAug 31, 2024Canadian Institutes of Health Research (CIHR), University of Manitoba
NCT06470061Phase 2Jul 31, 2024Northwestern University, Zaparackas and Knepper LTD
NCT07278128Phase 2/Phase 3 (Phase 3)Jun 22, 2024Tarbiat Modarres University
NCT06342830Phase 2Jun 20, 2024Ain Shams University
NCT06777303N/AJun 2, 2024Mansoura University
Showing 20 of 279 trials
Page 1 / 14

Organizations

Research & Development (266)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government14341996
Tel Aviv UniversityAcademic/Hospital10832005
University of Texas at HoustonAcademic/Hospital10832004
Ain Shams UniversityAcademic/Hospital8832016
National Nutrition and Food Technology InstituteGovernment7722015
Cairo UniversityAcademic/Hospital6532019
University of California, Los AngelesAcademic/Hospital6322003
Emory UniversityAcademic/Hospital5522010
Technion UniversityAcademic/Hospital5342004
Hebrew UniversityAcademic/Hospital4342007
University of HohenheimAcademic/Hospital4432011
University of North Carolina at Chapel HillAcademic/Hospital4422010
University of RochesterAcademic/Hospital4422008
Baylor UniversityAcademic/Hospital3322005
Canadian Institutes of Health Research (CIHR)Academic/Hospital3022011
Department of Veteran AffairsGovernment3312014
Fluminense Federal UniversityAcademic/Hospital3322018
German Federal Ministry of Education and ResearchGovernment3022011
Government of ThailandGovernment3122009
Johns Hopkins UniversityAcademic/Hospital3222005
266 organizations
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