petrolatum, white
Trade name: Vaseline
Small moleculeapproved
Approved
Feb 16, 2006
Vaseline is an American brand of petroleum jelly-based products owned by British multinational company Unilever. Products include plain petroleum jelly and a selection of skin creams, soaps, lotions, cleansers, and deodorants. — Wikipedia
Clinical trial activity
60 trials · 71 clinical orgs · 2 marketing orgs
Phase 1
14
Phase 2
14
Phase 3
4
Phase 4
11
Earliest trial started Dec 1, 2001 (NCT00162747)
Timeline
Indications
Approved for
Studied for
- Aging · Phase 4
- Anesthesia · Early Phase 1
- Bronchiectasis · Phase 4
- Burns · Phase 4
- Carcinoma, Squamous Cell · Phase 2
- Cicatrix, Hypertrophic · Phase 4
- COVID-19 · Phase 2
- Dermatitis, Atopic · Phase 4
- Dermatology · Early Phase 1
- Diabetes Mellitus, Type 2 · Phase 4
- Diabetic Foot · Phase 4
- Dupuytren Contracture · Phase 2
- Healthy Volunteers · Phase 1
- Immunotherapy · Phase 2
- Inflammation · Phase 4
- Keloid · Phase 4
- Keratosis, Actinic · Phase 4
- Leg Ulcer · Phase 4
- Organ Transplantation · Phase 2
- Pain · Phase 3
- Pityriasis · Phase 4
- Port-Wine Stain · Phase 2
- Post-Traumatic Headache · Phase 3
- Pressure Ulcer · Phase 4
- Psoriasis · Phase 2/Phase 3
- Radiodermatitis · Phase 1/Phase 2
- Scleroderma, Systemic · Phase 2
- Skin Aging · Phase 1
- Skin and Connective Tissue Diseases · Phase 1
- Skin Diseases · Phase 4
- Skin Neoplasms · Phase 2
- Staphylococcus · Phase 2
- Sunburn · Phase 2
- Tendinopathy · Phase 1
- Toxicity Tests · Phase 2
- Warts · Phase 2
- Wound Healing · Phase 1
- Wounds and Injuries · Phase 4
Mechanism of action
- Unspecified targetOTHER
Unknown
- UnclearUnclear
Unclear unclear
Combination products
vusion
with miconazole, zinc oxide
Approval history
- approvedFeb 16, 2006
- approvedJun 1, 1872
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaVaseline ↗
- NCATS4T6H12BN9U ↗
- ChEMBLCHEMBL2108555 ↗
- ChEMBLCHEMBL1201719 ↗
Also known as
- maroline
- multi-hydrocarbon
- paraffinum album
- paraffinum flavum
- petrolatum
- petrolatum
- petrolatum
- petrolatum
- petrolatum
- petrolatum
- petrolatum,amber
- petrolatum base
- petrolatum,white
- petrolatum,white
- petrolatum, white
- petrolatum, white
- petrolatum, white
- petroleum jelly
- petroleum jelly
- petroleum jelly
- petroleum jelly
- soft paraffin
- vaseline
- vaseline
- vaseline
- white petrolatum
- white petrolatum
- white petrolatum
- white, soft paraffin
- yellow petrolatum
- yellow soft paraffin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07183423 | N/A | Aug 31, 2025 | Makati Medical Center |
| NCT06750653 | Phase 4 | Dec 27, 2024 | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), University of California, San Francisco |
| NCT06267066 | N/A | Mar 1, 2024 | Cairo University |
| NCT06321991 | Phase 2 | Feb 15, 2024 | Katholieke Universiteit Leuven |
| NCT07169032 | Early Phase 1 (Phase 1) | Jan 1, 2024 | Jinan University |
| NCT05312645 | Phase 3 | Jan 31, 2023 | Loma Linda University |
| NCT05436535 | Phase 4 | Nov 21, 2022 | National Institute of Allergy and Infectious Diseases (NIAID), National Jewish Health |
| NCT05618912 | N/A | Oct 17, 2022 | Indiana University |
| NCT05449392 | Phase 1 | Sep 1, 2022 | Bill and Melinda Gates Foundation, Yale University |
| NCT05194969 | N/A | Apr 25, 2022 | University of North Carolina at Chapel Hill |
| NCT05314127 | Phase 2 | Apr 15, 2022 | Zagazig University |
| NCT05254925 | Phase 2 | Feb 28, 2022 | DSM, Eurofins |
| NCT05260359 | Phase 2 | Feb 23, 2022 | DSM, Eurofins |
| NCT05457491 | Phase 1 | Oct 1, 2021 | Mayo Clinic |
| NCT04642287 | Phase 2 | Jul 31, 2021 | Harvard University, Washington University in St. Louis |
| NCT04851522 | Early Phase 1 (Phase 1) | Jun 9, 2021 | Harvard University |
| NCT04951349 | Phase 2 | Jan 21, 2021 | Hospital Modular - Covid-19, Hospital Punta Pacifica, Hospital Santo Tomas, Turn Therapeutics, University of Alabama, Birmingham |
| NCT05353374 | N/A | Jan 1, 2021 | University of Indonesia |
| NCT04329221 | Phase 2 | Jun 30, 2020 | Harvard University, Washington University in St. Louis |
| NCT04426409 | N/A | Jun 24, 2020 | Ajou University |
Showing 20 of 60 trials
Page 1 / 3
Organizations
Research & Development (71)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Harvard University | Academic/Hospital | 3 | 3 | 2 | 2020 |
| Healthpoint | For profit | 3 | 3 | 2 | 2010 |
| Leo Pharma | For profit | 3 | 2 | 1 | 2013 |
| Mahidol University | Academic/Hospital | 3 | 3 | 2 | 2010 |
| Washington University in St. Louis | Academic/Hospital | 3 | 1 | 2 | 2013 |
| DSM | For profit | 2 | 2 | 1 | 2022 |
| Eurofins | For profit | 2 | 0 | 1 | 2022 |
| Indiana University | Academic/Hospital | 2 | 2 | 2 | 2019 |
| Johnson and Johnson | For profit | 2 | 1 | 2 | 2005 |
| Northwestern University | Academic/Hospital | 2 | 2 | 2 | 2005 |
| University of Arizona | Academic/Hospital | 2 | 2 | 2 | 2017 |
| University of Indonesia | Academic/Hospital | 2 | 2 | 2 | 2018 |
| Zagazig University | Academic/Hospital | 2 | 2 | 2 | 2019 |
| Ajou University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Bangladesh Medical University | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Bill and Melinda Gates Foundation | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Biosplice Therapeutics | For profit | 1 | 1 | 1 | 2017 |
| Cairo University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| China Medical University | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2015 |
71 organizations
Page 1 / 4
Marketing (2)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Chesebrough Manufacturing Company | For profit | NDA | — |
| Mylan | For profit | NDA2 | Feb 16, 2006 |