colloidal silver

Small moleculemarketed

Approved

Jan 1, 1899

The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections. The limited evidence available shows that silver coatings on endotracheal breathing tubes may reduce the incidence of ventilator-associated pneumonia. There is tentative evidence that using silver-alloy indwelling catheters for short-term catheterizing will reduce the risk of catheter-acquired urinary tract infections. — Wikipedia

Clinical trial activity

13 trials · 12 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
4
Phase 3
1
Phase 4
2

Earliest trial started Dec 1, 2010 (NCT01243320)

Timeline

1890s

  1. Jan 1, 1899

    Evidence of US Marketing

2010s

  1. Jan 1, 2010

    Earliest Phase 1 Sponsor(trial)

2020s

  1. Jan 1, 2020

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • Unspecified targetUnclear

    unclear

Approval history

  • approvedJan 1, 1899

Chemistry & pharmacology

Loading structure…

SMILES

[Ag+]
Mol. weight
107.87 g/mol
Chirality
Achiral Molecule
Inorganic
Yes
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • argentum metallicum
  • collargol
  • colloidal silver
  • colloidal silver
  • colloidal silver
  • colloidal silver
  • colloidal silver
  • e174
  • e174
  • nanosilver
  • nanosilver
  • silver
  • silver
  • silver
  • silver
  • silver
  • silver colloid
  • silver colloid
  • silver colloidal
  • silver, colloidal
  • silver, colloidal
  • silver microparticles
  • silver nanoparticles
  • silver nanoparticles

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07200063N/AJan 31, 2026Cairo University
NCT05850819N/AJul 1, 2022Melaka Manipal Medical College
NCT05255913N/AMar 31, 2022Alexandria University
NCT05206578Phase 3Dec 8, 2020Ahn-Gook Pharmaceuticals Co.,Ltd
NCT04978025N/ANov 1, 2020Hôpital Universitaire Sahloul
NCT03692286Phase 4Oct 15, 2018Cairo University
NCT03243201Phase 1Jan 31, 2018Washington University in St. Louis
NCT02584153Phase 1Jul 1, 2017University of California, San Francisco
NCT02581488Phase 4Oct 1, 2015Smith & Nephew
NCT02403479Phase 1/Phase 2 (Phase 2)Sep 1, 2015Schulich School of Medicine and Dentistry, University of Western Ontario
NCT02652169N/AJun 1, 2014University of Vienna
NCT01405794Phase 1/Phase 2 (Phase 2)Jul 1, 2011University of Utah
NCT01243320Phase 1/Phase 2 (Phase 2)Dec 1, 2010University of Utah
Showing 13 of 13 trials
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Organizations

Research & Development (12)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Cairo UniversityAcademic/Hospital2222018
University of UtahAcademic/Hospital2212010
Ahn-Gook Pharmaceuticals Co.,LtdFor profit1112020
Alexandria UniversityAcademic/Hospital1112022
Hôpital Universitaire SahloulAcademic/Hospital1112020
Melaka Manipal Medical CollegeAcademic/Hospital1112022
Schulich School of Medicine and DentistryAcademic/Hospital1012015
Smith & NephewFor profit1112015
University of California, San FranciscoAcademic/Hospital1112017
University of ViennaAcademic/Hospital1112014
University of Western OntarioAcademic/Hospital1112015
Washington University in St. LouisAcademic/Hospital1112018
12 organizations
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