glutaraldehyde

Small moleculeexperimental

Glutaraldehyde is an organic compound with the formula (CH2)3(CHO)2. The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert. Because the molecule has two aldehyde functional groups, glutaraldehyde can crosslink substances with primary amine groups, through condensation. Crosslinking can rigidify and deactivate proteins and other molecules that are critical for normal biological function, such as DNA, and so glutaraldehyde solutions are effective biocides and fixatives. It is sold under the brandnames Cidex and Glutaral. As a disinfectant, it is used to sterilize surgical instruments. — Wikipedia

Clinical trial activity

6 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
1
Phase 4
0

Earliest trial started Oct 26, 2017 (NCT03894839)

Timeline

2020s

  1. Jan 1, 2025

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetCROSS-LINKING AGENT

    protein

  • Unspecified targetCROSS-LINKING AGENT

    DNA

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07188142Phase 2/Phase 3 (Phase 3)Dec 1, 2025Margalla Institute of Health Sciences
NCT06759454N/AJun 30, 2025College of Physicians and Surgeons Pakistan, Saidu College of Dentistry
NCT04248803N/AFeb 20, 2020Tamil Nadu Dr.M.G.R.Medical University
NCT04351412N/AJan 10, 2020King Abdul-Aziz University
NCT04207450N/AMar 15, 2019Universidade Federal do Para
NCT03894839N/AOct 26, 2017Yuzuncu Yıl University
Showing 6 of 6 trials
Page 1 / 1

Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
College of Physicians and Surgeons PakistanAcademic/Hospital1112025
King Abdul-Aziz UniversityAcademic/Hospital1112020
Margalla Institute of Health SciencesAcademic/Hospital1112025
Saidu College of DentistryAcademic/Hospital1012025
Tamil Nadu Dr.M.G.R.Medical UniversityAcademic/Hospital1112020
Universidade Federal do ParaAcademic/Hospital1112019
Yuzuncu Yıl UniversityAcademic/Hospital1112017
7 organizations
Page 1 / 1