glutaraldehyde
Glutaraldehyde is an organic compound with the formula (CH2)3(CHO)2. The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert. Because the molecule has two aldehyde functional groups, glutaraldehyde can crosslink substances with primary amine groups, through condensation. Crosslinking can rigidify and deactivate proteins and other molecules that are critical for normal biological function, such as DNA, and so glutaraldehyde solutions are effective biocides and fixatives. It is sold under the brandnames Cidex and Glutaral. As a disinfectant, it is used to sterilize surgical instruments. — Wikipedia
Clinical trial activity
6 trials · 7 clinical orgs · 0 marketing orgs
Earliest trial started Oct 26, 2017 (NCT03894839)
Timeline
2020s
- Jan 1, 2025
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Unspecified targetCROSS-LINKING AGENT
protein
- Unspecified targetCROSS-LINKING AGENT
DNA
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGlutaraldehyde ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07188142 | Phase 2/Phase 3 (Phase 3) | Dec 1, 2025 | Margalla Institute of Health Sciences |
| NCT06759454 | N/A | Jun 30, 2025 | College of Physicians and Surgeons Pakistan, Saidu College of Dentistry |
| NCT04248803 | N/A | Feb 20, 2020 | Tamil Nadu Dr.M.G.R.Medical University |
| NCT04351412 | N/A | Jan 10, 2020 | King Abdul-Aziz University |
| NCT04207450 | N/A | Mar 15, 2019 | Universidade Federal do Para |
| NCT03894839 | N/A | Oct 26, 2017 | Yuzuncu Yıl University |
Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| College of Physicians and Surgeons Pakistan | Academic/Hospital | 1 | 1 | 1 | 2025 |
| King Abdul-Aziz University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Margalla Institute of Health Sciences | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Saidu College of Dentistry | Academic/Hospital | 1 | 0 | 1 | 2025 |
| Tamil Nadu Dr.M.G.R.Medical University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Universidade Federal do Para | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Yuzuncu Yıl University | Academic/Hospital | 1 | 1 | 1 | 2017 |