ozone
Ozone, also called trioxygen, is an inorganic molecule with the chemical formula O3. It is a pale-blue gas with a distinctively pungent odor. It is an allotrope of oxygen that is much less stable than the diatomic allotrope O2, breaking down in the lower atmosphere to O2 (dioxygen). Ozone is formed from dioxygen by the action of ultraviolet (UV) light and electrical discharges within the Earth's atmosphere. It is present in very low concentrations throughout the atmosphere, with its highest concentration high in the ozone layer of the stratosphere, which absorbs most of the Sun's ultraviolet (UV) radiation. — Wikipedia
Clinical trial activity
76 trials · 67 clinical orgs · 0 marketing orgs
Earliest trial started Feb 28, 2002 (NCT00840528)
Timeline
Indications
Approved for
Studied for
- Acute Lung Injury · Phase 1
- Asthma · Phase 4
- Back Pain · Phase 4
- Coronavirus Infections · Phase 2
- COVID-19 · Phase 3
- Cystitis, Interstitial · Phase 2
- Dentin Sensitivity · Phase 2
- Dietary Supplements · Phase 1
- Drug-Related Side Effects and Adverse Reactions · Phase 2/Phase 3
- Healthy Volunteers · Phase 1
- Hepatitis B, Chronic · Phase 4
- Keratitis · Phase 3
- Lumbar Vertebrae · Phase 2
- Lung Diseases · Early Phase 1
- Mandibular Diseases · Phase 3
- Myocardial Ischemia · Phase 2/Phase 3
- Neuralgia · Phase 2/Phase 3
- Neutrophils · Phase 1
- Osteoarthritis, Knee · Phase 3
- Osteonecrosis · Phase 1/Phase 2
- Ozone · Phase 4
- Pain · Phase 2/Phase 3
- Periodontal Pocket · Phase 1
- Periodontitis · Phase 2
- Pneumonia, Viral · Phase 2
- Sepsis · Phase 4
- Signs and Symptoms · Phase 1
- Tooth Abnormalities · Phase 2
Mechanism of action
- Molecular identity unknownOXIDATIVE ENZYME
Molecular identity unknown oxidative enzyme
Chemistry & pharmacology
SMILES
O=[O+][O-]- Mol. weight
- 48 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaOzone ↗
- ChEMBLCHEMBL2447938 ↗
Also known as
- ozone
- ozone
- ozone
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07199712 | N/A | Oct 1, 2025 | University of Pavia |
| NCT07106333 | N/A | Aug 1, 2025 | Menoufia University |
| NCT07153627 | N/A | May 1, 2025 | Al Azhar University |
| NCT06802354 | Phase 3 | Dec 1, 2024 | University of East Sarajevo |
| NCT06943989 | N/A | Nov 5, 2024 | Environmental Protection Agency |
| NCT06513754 | N/A | Sep 30, 2024 | Natural Sciences and Engineering Research Council, Canada, University of British Columbia |
| NCT07134972 | N/A | Jan 14, 2024 | Istanbul University |
| NCT06133712 | N/A | Nov 1, 2023 | Tanta University |
| NCT06130618 | N/A | Sep 1, 2023 | Ankara City Hospital Bilkent, Ankara Yildirim Beyazıt University |
| NCT05984121 | N/A | Jul 17, 2023 | Ahi Evran University Education and Research Hospital |
| NCT05914350 | N/A | Jun 23, 2023 | Tanta University |
| NCT05773001 | Phase 1 | May 18, 2023 | Duke University, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH) |
| NCT05875506 | N/A | May 1, 2023 | Minia University |
| NCT05837494 | N/A | May 1, 2023 | Tanta University |
| NCT05824052 | N/A | Apr 21, 2023 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey, Uskudar University |
| NCT05794087 | N/A | Feb 7, 2023 | National Institute of Environmental Health Sciences (NIEHS), Rutgers University |
| NCT05689996 | Phase 3 | Jan 31, 2023 | Assiut University |
| NCT05690100 | N/A | Jan 31, 2023 | Cairo University |
| NCT05538078 | N/A | Oct 15, 2022 | Cairo University |
| NCT05680831 | Phase 1 | Oct 13, 2022 | Environmental Protection Agency, University of North Carolina at Chapel Hill |