lactobacillus reuteri
Cell therapyexperimental
Clinical trial activity
186 trials · 200 clinical orgs · 0 marketing orgs
Phase 1
21
Phase 2
41
Phase 3
23
Phase 4
22
Earliest trial started Feb 1, 2001 (NCT01285830)
Timeline
Indications
Approved for
Studied for
- Abdominal Pain · Phase 4
- Allergy and Immunology · Phase 2
- Anorexia Nervosa · Phase 2/Phase 3
- Antibiotic Prophylaxis · Phase 2
- Bacteriuria · Phase 1
- Bone Diseases, Metabolic · Phase 2
- Brain Concussion · Phase 1
- Bronchopulmonary Dysplasia · Phase 3
- Candidiasis, Vulvovaginal · Phase 1
- Carcinoma, Non-Small-Cell Lung · Phase 3
- Chronic Periodontitis · Phase 1
- Clostridium Infections · Phase 3
- Colic · Phase 4
- Colitis, Ulcerative · Phase 2
- Colonic Neoplasms · Phase 2
- Constipation · Phase 4
- Cross Infection · Phase 3
- Crying · Phase 3
- Cystic Fibrosis · Phase 4
- Death · Phase 3
- Dental Caries · Phase 4
- Dental Plaque · Phase 2
- Diabetes Mellitus, Type 2 · Phase 2
- Diarrhea · Phase 4
- Disease Eradication · Phase 4
- Diverticulitis · Phase 3
- Diverticulum · Phase 3
- Dysbiosis · Phase 4
- Dyspepsia · Phase 3
- Enterocolitis, Necrotizing · Phase 3
- Gastroenteritis · Phase 3
- Gastroesophageal Reflux · Phase 3
- Growth and Development · Phase 2
- Halitosis · Phase 4
- Head and Neck Neoplasms · Phase 2
- Healthy Volunteers · Phase 3
- Helicobacter Infections · Phase 4
- Helicobacter pylori · Phase 4
- HIV Infections · Phase 2/Phase 3
- Hypercholesterolemia · Phase 2
- Infections · Phase 1/Phase 2
- Insulin Resistance · Phase 4
- Intestinal Neoplasms · Phase 1
- Laryngopharyngeal Reflux · Phase 4
- Leukomalacia, Periventricular · Phase 3
- Live Birth · Phase 4
- Mastitis · Phase 2/Phase 3
- Mucositis · Phase 2
- Neonatology · Phase 2
- Obesity · Phase 4
- Pancreatic Neoplasms · Phase 2
- Pregnancy · Phase 1/Phase 2
- Premature Birth · Phase 3
- Rotavirus Infections · Phase 4
- Safety · Phase 1/Phase 2
- Sepsis · Phase 3
- Spinal Cord Injuries · Phase 1
- Stress Disorders, Post-Traumatic · Phase 1
- Urinary Tract Infections · Phase 2
- Vaginosis, Bacterial · Phase 4
Mechanism of action
- microbiotaTissue restoration
microbiota tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- atcc pta 6475
- biogaia-dsm17938
- ibp-9414
- lactobacilli rc-14
- lactobacilli reuteri
- lactobacillus rc-14
- lactobacillus reuteri
- lactobacillus reuteri 17938
- lactobacillus reuteri dsm17938
- lactobacillus reuteri dsm 17938
- lactobacillus reuteri dsmz 17648
- lactobacillus reuterii
- lactobacillus reuteri rc -14
- lactobacillus reuteri rc-14
- lactobacillus reuteri, rc-14
- l. retueri
- l. reuteri
- l. reuteri dsm 17938
- l. reuteri ncimb 30242
- l. reuteri rc-14
- probiotic strains of l reuteri
- pta 5289
- rillus
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07163637 | N/A | Sep 8, 2025 | Citruslabs, Novonesis |
| NCT07190859 | N/A | Aug 4, 2025 | BioGaia AB |
| NCT06782061 | N/A | Dec 26, 2024 | Southern Medical University |
| NCT06462651 | N/A | Oct 31, 2024 | BioGaia AB |
| NCT06436976 | Phase 2 | Mar 1, 2024 | AtoGen Co. Ltd, Chungnam National University |
| NCT06672406 | N/A | Jan 1, 2024 | University of Hasanuddin |
| NCT06285591 | N/A | Nov 10, 2023 | People's Liberation Army of China, Sichuan University |
| NCT05942586 | N/A | May 22, 2023 | National University of Ireland, Novonesis |
| NCT05703659 | N/A | Mar 1, 2023 | University of Florida |
| NCT07216729 | N/A | Feb 20, 2023 | University of Colorado, Boulder |
| NCT06959043 | N/A | Nov 22, 2022 | Conselho Nacional de Desenvolvimento Científico e Tecnológico, University of Sao Paulo |
| NCT05492448 | N/A | Sep 19, 2022 | glac Biotech Co., Ltd. |
| NCT05512234 | N/A | Jul 13, 2022 | Atlantia Food Clinical Trials, BioGaia AB, Clinical Trial Consultants AB |
| NCT05852990 | Phase 3 | Mar 1, 2022 | Government of Mexico |
| NCT05738369 | N/A | Feb 14, 2022 | Jordan University |
| NCT05118919 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2021 | BioGaia AB, Uppsala University |
| NCT04634201 | N/A | Sep 30, 2021 | Sunstar, University of Lille |
| NCT05407090 | N/A | Aug 2, 2021 | Medical University of Gdansk, Pomeranian Medical University |
| NCT04925700 | N/A | Jul 1, 2021 | University of Iowa |
| NCT04886778 | N/A | Jun 1, 2021 | Southern Medical University, Zhujiang Hospital |
Showing 20 of 186 trials
Page 1 / 10
Organizations
Research & Development (200)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| BioGaia AB | For profit | 43 | 11 | 4 | 2001 |
| University of Bari | Academic/Hospital | 8 | 7 | 3 | 2009 |
| University of Copenhagen | Academic/Hospital | 8 | 8 | 1 | 2010 |
| Hospital General Dr. Manuel Gea Gonzalez | Academic/Hospital | 5 | 5 | 1 | 2017 |
| Medical University of Warsaw | Academic/Hospital | 5 | 5 | 3 | 2009 |
| University of Western Ontario | Academic/Hospital | 5 | 3 | 3 | 2007 |
| Baylor University | Academic/Hospital | 4 | 3 | 3 | 2008 |
| Karolinska Institute | Academic/Hospital | 4 | 0 | 2 | 2001 |
| Micropharma Limited | For profit | 4 | 4 | 1 | 2008 |
| University of Gothenburg | Academic/Hospital | 4 | 4 | 2 | 2015 |
| Emek Medical Center | Academic/Hospital | 3 | 3 | 1 | 2016 |
| Johns Hopkins University | Academic/Hospital | 3 | 0 | 1 | 2010 |
| Linkoping University | Academic/Hospital | 3 | 1 | 2 | 2001 |
| National Center for Complementary and Integrative Health (NCCIH) | Government | 3 | 0 | 1 | 2009 |
| Tulane University | Academic/Hospital | 3 | 3 | 1 | 2010 |
| University of Florida | Academic/Hospital | 3 | 1 | 3 | 2016 |
| University of Indonesia | Academic/Hospital | 3 | 1 | 2 | 2017 |
| University of Ljubljana | Academic/Hospital | 3 | 2 | 2 | 2012 |
| University of Toronto | Academic/Hospital | 3 | 3 | 3 | 2005 |
| University of Zagreb | Academic/Hospital | 3 | 2 | 3 | 2013 |
200 organizations
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