erythritol
Small moleculeexperimental
Erythritol (, ) is an organic compound, the naturally occurring achiral meso four-carbon sugar alcohol (or polyol). It is the reduced form of either D- or L-erythrose and one of the two reduced forms of erythrulose. It is used as a food additive and sugar substitute. It is synthesized from corn using enzymes and fermentation. Its formula is C4H10O4, or HO(CH2)(CHOH)2(CH2)OH. — Wikipedia
Clinical trial activity
18 trials · 16 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
1
Phase 4
3
Earliest trial started Mar 31, 2006 (NCT02016703)
Timeline
Indications
Approved for
Mechanism of action
- Streptococcus mutansINHIBITOR
Streptococcus mutans inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaErythritol ↗
Also known as
- erythritol
- erythritol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06723054 | N/A | Feb 1, 2023 | University of Zurich |
| NCT06998160 | N/A | Jul 5, 2022 | Changsha Stomatological Hospital |
| NCT05279183 | N/A | Mar 17, 2022 | St. Claraspital Basel, University of Basel |
| NCT04651088 | Early Phase 1 (Phase 1) | Dec 1, 2021 | The University of Texas, Dallas |
| NCT04966299 | N/A | Aug 18, 2021 | St. Claraspital Basel, University of Basel |
| NCT04731363 | N/A | Mar 10, 2021 | The Cleveland Clinic |
| NCT04713137 | N/A | Feb 8, 2021 | St. Claraspital Basel, University of Basel |
| NCT04169945 | N/A | Dec 31, 2019 | University of Malaya |
| NCT04095975 | Phase 4 | Aug 28, 2019 | University of Wisconsin |
| NCT04027283 | N/A | Aug 1, 2019 | St. Claraspital Basel, University of Basel |
| NCT03039478 | N/A | Feb 24, 2017 | University of Bern |
| NCT02563847 | N/A | May 1, 2014 | University of Bern |
| NCT02823249 | N/A | May 1, 2014 | University of Bern |
| NCT02023853 | Phase 4 | Dec 1, 2013 | Institute for Professional Education in Dentistry, Proed |
| NCT02023840 | Phase 4 | Dec 1, 2013 | Institute for Professional Education in Dentistry, Proed |
| NCT01609088 | N/A | May 1, 2012 | Boston University, Cargill |
| NCT01062633 | Phase 2/Phase 3 (Phase 3) | Jan 1, 2008 | University of Tartu, University of Turku |
| NCT02016703 | N/A | Mar 31, 2006 | Cargill, Pasteur Merieux |
Showing 18 of 18 trials
Page 1 / 1
Organizations
Research & Development (16)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| St. Claraspital Basel | Academic/Hospital | 4 | 0 | 1 | 2019 |
| University of Basel | Academic/Hospital | 4 | 4 | 1 | 2019 |
| University of Bern | Academic/Hospital | 3 | 3 | 1 | 2014 |
| Cargill | For profit | 2 | 1 | 1 | 2006 |
| Institute for Professional Education in Dentistry | Academic/Hospital | 2 | 2 | 1 | 2013 |
| Proed | Academic/Hospital | 2 | 0 | 1 | 2013 |
| Boston University | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Changsha Stomatological Hospital | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Pasteur Merieux | For profit | 1 | 0 | 1 | 2006 |
| The Cleveland Clinic | Academic/Hospital | 1 | 1 | 1 | 2021 |
| The University of Texas, Dallas | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Malaya | Academic/Hospital | 1 | 1 | 1 | 2019 |
| University of Tartu | Academic/Hospital | 1 | 1 | 1 | 2008 |
| University of Turku | Academic/Hospital | 1 | 0 | 1 | 2008 |
| University of Wisconsin | Academic/Hospital | 1 | 1 | 1 | 2019 |
| University of Zurich | Academic/Hospital | 1 | 1 | 1 | 2023 |
16 organizations
Page 1 / 1