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Diabetic Foot
Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.
Drugs by status
Approved for this indication (2)
Phase 4 trials (28)
- levofloxacin
- metronidazole
- colloidal silver
- linezolid
- oak extract
- petrolatum, white
- aztreonam
- procaine benzylpenicillin
- clavulanate
- human placenta hydrolysate
- insulin glargine
- centella asiatica
- daptomycin
- hemoglobin
- vitamin c
- saxagliptin
- aluminum hydroxide
- vancomycin
- yunnan baiyao
- amniotic epithelial cells
- collagenase clostridium histolyticum
- gentamicin
- oxygen
- clindamycin
- chlorhexidine
- bacitracin
- plectranthus amboinicus
- umbilical cord blood platelet lysate
Phase 3 trials (38)
- iron
- vitamin e
- acetylcysteine
- astragalus membranaceus
- chitosan
- esmolol
- energi-f703
- epidermal growth factor
- tigecycline
- platelet-rich plasma
- nitric oxide
- pirfenidone
- becaplermin
- sitagliptin
- pexiganan acetate
- enoxaparin
- urokinase
- allogeneic adipose derived mesenchymal stem cell
- cord blood hematopoietic stem cell
- vm202
- anacaulase
- panthenol
- radix rehmanniae
- salvigenin
- asiaticoside a
- moxifloxacin
- vitamin a
- ertapenem
- ofloxacin
- isosorbide
- +8 more
Phase 2 trials (75)
- metformin
- epoetin
- bone autograft
- cstc1
- deferoxamine
- doxycycline
- selinexor
- escharex
- gabapentin
- gam501
- glimepiride
- yuyang
- bone marrow derived mesenchymal stem cells
- ho/03/03
- i-020201
- lorazepam
- izn-6d4
- leucovorin
- ll37
- pravibismane
- nexagon
- allogeneic stem cells
- peripheral blood lymphocytes
- platelet poor plasma
- nicotine
- propolis
- surfactant
- platelets
- hyaluronic acid
- telbermin
- +45 more
Phase 1 trials (18)
- leptospermum honey
- tobramycin
- boron
- expressgraft-c9t1 skin tissue
- fgf-1
- fusidic acid
- cow milk
- platelet rich fibrin
- methylene blue
- tang ning tongluo
- itraconazole
- autologous bone marrow derived mesenchymal cells
- stearic acid
- sodium chloride
- ethacridine lactate
- nox-1416
- adipose tissue derived extracellular vesicles
- huafu shengji
Other trials (21)
- vitamin d3
- acellular dermal matrix
- amniotic membrane
- urea
- cefazolin
- epiceram
- insulin human
- collagen-silver
- ropivacaine
- lidocaine
- acetylsalicylic acid
- sulfamethoxazole
- bupivacaine
- antibiofilmogramme
- autologous endothelial progenitor cells
- allogeneic blood cells
- hypochlorous acid
- trimethoprim
- dexamethasone
- methylcobalamin
- water
Organizations
Organization Involved with Phase 4 Indications (25)
- Smith & Nephew
- Merck
- Pfizer
- Wyeth
- Clinical Alliance for Research & Education - Infectious Diseases, LLC.
- Cubist
- Healthpoint
- Milton S. Hershey Medical Center
- Xinqiao Hospital of Chongqing
- University of Pittsburgh
- Georgetown University
- Jawaharlal Nehru Medical College
- Postgraduate Institute of Medical Education and Research
- Universidad de Guanajuato
- University of North Dakota
- All India Institute of Medical Sciences
- Pennsylvania State University
- Associated Foot & Ankle Specialists
- Amrita Institute of Medical Sciences
- Institute of Post Graduate Medical Education & Research
- P.D. Hinduja Hospital and Medical Research Centre, Mumbai
- Vancouver Island Health Authority
- Integra LifeSciences Corporation
- University of Geneva
- People's Liberation Army of China
Organization Involved with Phase 3 Indications (73)
- Adocia
- Osiris Therapeutics
- Anterogen Co., Ltd.
- Bayer
- Biotec Pharmacon ASA
- Dipexium Pharmaceuticals, Inc.
- European Egyptian Pharmaceutical Industries
- FirstString Research, Inc.
- Genaera Corporation
- GWT-TUD GmbH
- INC Research
- Innocoll
- MacroChem Corporation
- Microbio Co Ltd
- Novalead Pharma Private Limited
- Olympus Biotech Corporation
- Tissue Tech Inc.
- Virchow Group
- Daewoong Pharmaceutical Co. LTD.
- Derma Sciences, Inc.
- Rovi Pharmaceuticals Laboratories
- Fundación Cardiovascular de Colombia
- Ajou University
- Alexandria University
- Cairo University
- Centro Nazionale Sangue
- Chang Gung University
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Korea University
- Mashhad University of Medical Sciences
- +43 more
Organization Involved with Phase 2 Indications (89)
- Celgene
- Cato Research
- Genentech
- CoMentis
- BioMed Valley Discoveries, Inc
- Bridge BioResearch Ltd.
- Gene Biotherapeutics, Inc.
- Catalysis SL
- Charsire Biotechnology Corp.
- Energenesis Biomedical Co., Ltd.
- FGK Clinical Research GmbH
- GlaxoSmithKline
- HealOr
- Izun Pharma Ltd
- Karyopharm Therapeutics Inc
- Lakewood-Amedex Inc
- Lynch Biologics LLC
- Microbion Corporation
- OXO Chemie
- NanoSHIFT LLC
- Ology Bioservices
- Pherecydes Pharma
- Remedor Biomed Ltd
- Royer Biomedical, Inc.
- Skingenix, Inc.
- Tissue Repair Company
- Transwell Biotech Co., Ltd.
- A2 Healthcare Taiwan Corporation
- Kuros Biosurgery AG
- TaiGen Biotechnology Co., Ltd.
- +59 more
Organization Involved with Phase 1 Indications (22)
- Roche
- Genzyme
- Mallinckrodt
- Phage Pharmaceuticals, Inc.
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Huazhong University of Science and Technology
- National Cheng Kung University
- New York University
- Assiut University
- Capital Medical University
- South China Research Center for Stem Cell and Regenerative Medicine
- Tel Aviv University
- University of Colorado, Denver
- Leiden University
- Southern Medical University
- Hebrew University
- Bezmialem University
- Spartanburg Regional Healthcare System
- Stratatech Corporation
- Cyberjaya University College of Medical Sciences
- Blue Blood Biotech Corp.
- Steno Diabetes Center Copenhagen
Organization Involved with Other Experimental Indications (26)
- MiMedx Group, Inc.
- Sonescence, Inc.
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- University of Manitoba
- Allegiance Health
- Faculdade de Medicina do ABC
- Human Stem Cell Institute, Russia
- Mansoura University
- Nanjing Medical University
- Northwestern University
- Services Hospital, Lahore
- Sutter Health
- Universidad Complutense de Madrid
- University of Copenhagen
- Pavlov First Saint Petersburg State Medical University
- University of Lyon
- King Hamad University
- Sonoma West Medical Center
- Stellenbosch University
- Vidnoe District Hospital
- Heritage Medical Research Institute
- Cook Medical
- Solsys Medical
- Udayana University
- ACell Inc.
- University of Las Palmas de Gran Canaria