platelets
Cell therapymarketed
Approved
Jun 1, 1910
Platelets or thrombocytes are a part of blood whose function is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm from megakaryocytes which reside in bone marrow or lung tissue, and then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates, thrombocytes circulate as intact mononuclear cells. — Wikipedia
Clinical trial activity
58 trials · 90 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
22
Phase 3
14
Phase 4
9
Earliest trial started Sep 1, 1999 (NCT00038012)
Timeline
Indications
Approved for
Studied for
- Aspirin · Phase 2
- Atrial Fibrillation · Phase 4
- Bleeding Time · Phase 3
- Blood Coagulation · Phase 4
- Blood Loss, Surgical · Phase 3
- Blood Platelet Disorders · Phase 2
- Blood Platelets · Phase 2/Phase 3
- Bone Marrow Diseases · Phase 2
- Brain Injuries, Traumatic · Phase 2
- Cardiopulmonary Bypass · Phase 2/Phase 3
- Coronary Artery Disease · Phase 2
- Diabetes Mellitus, Type 2 · Phase 4
- Diabetic Foot · Phase 1/Phase 2
- Drug-Related Side Effects and Adverse Reactions · Phase 4
- Ductus Arteriosus, Patent · Phase 3
- Gingival Recession · Phase 2
- Healthy Volunteers · Early Phase 1
- Heart Valve Diseases · Phase 2
- Hematologic Diseases · Phase 4
- Hematologic Neoplasms · Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 2/Phase 3
- Hemorrhage · Phase 3
- Kidney Diseases · Phase 4
- Leukemia, Myeloid · Phase 3
- Liver Cirrhosis · Phase 4
- Myelodysplastic Syndromes · Phase 2
- Myeloproliferative Disorders · Phase 2
- Platelet-Rich Fibrin · Phase 4
- Platelet-Rich Plasma · Phase 4
- Platelet Transfusion · Phase 4
- Purpura, Thrombocytopenic, Idiopathic · Phase 3
- Rotator Cuff Injuries · Phase 3
- Scleroderma, Systemic · Phase 2/Phase 3
- Tennis Elbow · Phase 3
- Thoracic Surgery · Phase 2/Phase 3
- Thrombocytopenia · Phase 4
- Traumatology · Phase 3
- Urological Manifestations · Phase 2
- Wounds and Injuries · Phase 3
Mechanism of action
- PlateletSupplementation
Platelet supplementation
Approval history
- approvedJun 1, 1910
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPlatelet ↗
- NCATSV82T6JEZ99 ↗
- ChEMBLCHEMBL2108774 ↗
- ChEMBLCHEMBL2108632 ↗
- WikipediaPlatelet transfusion ↗
Also known as
- platelet
- platelet
- platelet concentrate
- platelets
- platelets
- platelets
- thrombosomes
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07020559 | Phase 4 | Apr 30, 2026 | Peking University |
| NCT07064954 | Phase 2/Phase 3 (Phase 3) | Sep 1, 2025 | University of Toronto |
| NCT06613425 | Phase 4 | Aug 1, 2024 | People's Liberation Army of China |
| NCT05820126 | Phase 2 | Sep 5, 2023 | University of Ottawa |
| NCT06936358 | N/A | Aug 22, 2023 | Alexandria University |
| NCT05771831 | Phase 2 | Mar 15, 2023 | University of Copenhagen |
| NCT05667805 | Phase 4 | Jan 1, 2023 | Medical University of Vienna |
| NCT05744726 | N/A | Jan 1, 2023 | Altamash Institute of Dental Medicine, Jinnah Postgraduate Medical Centre |
| NCT05502809 | Phase 3 | Jan 1, 2023 | Erasmus University Rotterdam, Rijnstate Arnhem |
| NCT05648032 | Phase 3 | Oct 6, 2022 | National Taiwan University |
| NCT05660811 | Phase 4 | Sep 28, 2022 | Government of Poland, Medical University of Warsaw |
| NCT05220787 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2022 | Bloodworks Northwest, Department of Defense |
| NCT04726410 | Phase 2 | Dec 31, 2021 | Department of Defense, University of Pittsburgh |
| NCT04667468 | Phase 2 | Dec 1, 2021 | Department of Defense, University of Pittsburgh |
| NCT04834414 | Phase 3 | Oct 21, 2021 | Department of Defense, University of Minnesota, University of Pittsburgh, University of Utah, Washington University in St. Louis |
| NCT04709705 | Phase 2/Phase 3 (Phase 3) | Sep 30, 2021 | Cellphire, Inc., MaineGeneral Health, United States Army, University of Oklahoma |
| NCT04631211 | Phase 2 | Dec 31, 2020 | Cellphire, Inc., Department of Health and Human Services, University of Washington |
| NCT04431999 | Phase 3 | Sep 30, 2020 | Direction Centrale du Service de Santé des Armées, Ecoles militaires de santé de Lyon-Bron, Floralis, TIMC-IMAG |
| NCT04202198 | Phase 2 | Nov 22, 2019 | Krishnadevaraya College of Dental Sciences & Hospital |
| NCT05067608 | Phase 1/Phase 2 (Phase 2) | Oct 25, 2019 | Government of Singapore, Singapore General Hospital |
Showing 20 of 58 trials
Page 1 / 3
Organizations
Research & Development (90)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cellphire, Inc. | For profit | 5 | 5 | 4 | 2014 |
| Department of Defense | Government | 5 | 0 | 3 | 2012 |
| Department of Health and Human Services | Government | 3 | 0 | 2 | 2014 |
| Peking University | Academic/Hospital | 3 | 2 | 2 | 2018 |
| University of Pittsburgh | Academic/Hospital | 3 | 3 | 2 | 2021 |
| University of Texas at Houston | Academic/Hospital | 3 | 3 | 2 | 1999 |
| Emory University | Academic/Hospital | 2 | 2 | 1 | 2011 |
| Government of Poland | Government | 2 | 0 | 1 | 2018 |
| Medical University of Warsaw | Academic/Hospital | 2 | 2 | 1 | 2018 |
| People's Liberation Army of China | Government | 2 | 2 | 2 | 2012 |
| Puget Sound Blood Center | Academic/Hospital | 2 | 0 | 1 | 2014 |
| United States Army | Government | 2 | 1 | 2 | 2014 |
| University of Copenhagen | Academic/Hospital | 2 | 1 | 2 | 2010 |
| University of Oklahoma | Academic/Hospital | 2 | 0 | 2 | 2001 |
| University of Washington | Academic/Hospital | 2 | 0 | 2 | 2014 |
| Accumetrics, Inc. | For profit | 1 | 0 | 1 | 2009 |
| Akorn, Inc. | For profit | 1 | 0 | 1 | 2014 |
| Alexandria University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Altamash Institute of Dental Medicine | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Australian Red Cross | Academic/Hospital | 1 | 0 | 1 | 2019 |
90 organizations
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