pexiganan acetate
Peptideexperimental
Clinical trial activity
4 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
4
Phase 3
4
Phase 4
0
Earliest trial started Aug 1, 1994 (NCT00563433)
Timeline
1990s
- Jan 1, 1994
Earliest Phase 3 Sponsor(trial)
Indications
Mechanism of action
- Cell membraneDISRUPTING AGENT
Cell membrane disrupting agent
Chemistry & pharmacology
Loading structure…
SMILES
CC[C@H](C)[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)CC)C(C)C- Mol. weight
- 2477.22 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2108556 ↗
- ChEMBLCHEMBL1275802 ↗
Also known as
- locilex
- msi 78
- msi-78
- msi-78
- msi-78
- pexiganan
- pexiganan
- pexiganan
- pexiganan
- pexiganan acetate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01590758 | Phase 3 | Jun 1, 2014 | BioStrategics Consulting Ltd, Dipexium Pharmaceuticals, Inc. |
| NCT01594762 | Phase 3 | Jun 1, 2014 | BioStrategics Consulting Ltd, Dipexium Pharmaceuticals, Inc. |
| NCT00563394 | Phase 3 | Aug 1, 1994 | Genaera Corporation, MacroChem Corporation |
| NCT00563433 | Phase 3 | Aug 1, 1994 | Genaera Corporation, MacroChem Corporation |
Showing 4 of 4 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| BioStrategics Consulting Ltd | For profit | 2 | 0 | 1 | 2014 |
| Dipexium Pharmaceuticals, Inc. | For profit | 2 | 2 | 1 | 2014 |
| Genaera Corporation | For profit | 2 | 0 | 1 | 1994 |
| MacroChem Corporation | For profit | 2 | 2 | 1 | 1994 |
4 organizations
Page 1 / 1