fusidic acid
Trade name: Fucidin
Small moleculeexperimental
Fusidic acid, sold under the brand name Fucidin among others, is an antibiotic that is often used topically in creams or ointments and eyedrops but may also be given systemically as tablets or injections. As of October 2008, the global problem of advancing antimicrobial resistance has led to a renewed interest in its use. — Wikipedia
Clinical trial activity
16 trials · 13 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
9
Phase 3
6
Phase 4
3
Earliest trial started May 1, 2004 (NCT00986856)
Timeline
Indications
Approved for
Studied for
- Bacterial Infections · Phase 3
- Bone Diseases, Infectious · Phase 2/Phase 3
- Carcinoma, Non-Small-Cell Lung · Phase 3
- Cicatrix, Hypertrophic · Phase 3
- Conjunctivitis, Bacterial · Phase 3
- Cystic Fibrosis · Phase 2
- Diabetic Foot · Early Phase 1
- Eczema · Phase 3
- Endocarditis · Phase 4
- Impetigo · Phase 4
- Infections · Phase 2
- Inflammation · Phase 4
- Keloid · Phase 3
- Melioidosis · Phase 2
- Prosthesis-Related Infections · Phase 2
- Skin Diseases, Bacterial · Phase 2
Mechanism of action
- Elongation factor GINHIBITOR
Elongation factor G inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CC(=O)O[C@H]1C[C@@]2(C)[C@@H](C[C@@H](O)[C@H]3[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@@H]4CC[C@@]32C)/C1=C(\CCC=C(C)C)C(=O)O- Mol. weight
- 516.72 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL374975 ↗
- WikipediaFusidic acid ↗
- ChEMBLCHEMBL2106707 ↗
- ChEMBLCHEMBL1256987 ↗
Also known as
- cem-102
- cem-102
- flucidin
- fucidin caviject
- fucidine
- fucidine
- fucithalmic
- fucithalmic
- fucithalmic
- fusidate sodium
- fusidate sodium
- fusidic acid
- fusidic acid
- fusidic acid
- fusidic acid
- fusidic acid
- fusidic acid
- fusidic acid sodium
- fusidic acid sodium salt
- fusidinic acid
- silver fusidate
- silver fusidate
- silver fusidate
- silver fusidate
- silver fusidate
- silver fusidate
- sodium fusidate
- sodium fusidate
- sodium fusidate
- sodium fusidate
- sq-16360
- sq-16360
- sq-16603
- sq-16603
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06911424 | Phase 3 | Mar 21, 2025 | Baxis Pharmaceuticals, Inc. |
| NCT05641298 | Phase 2 | Dec 31, 2022 | Aceragen |
| NCT05398679 | Phase 4 | Jun 1, 2022 | University of Barcelona |
| NCT05105035 | Phase 2 | May 31, 2022 | Arrevus Inc. |
| NCT05353374 | N/A | Jan 1, 2021 | University of Indonesia |
| NCT03816618 | Early Phase 1 (Phase 1) | Feb 1, 2019 | Cyberjaya University College of Medical Sciences |
| NCT03395132 | Phase 3 | Jul 31, 2018 | Leo Pharma |
| NCT03052348 | N/A | Nov 1, 2017 | Red Cross War Memorial Childrens Hospital |
| NCT03105505 | Phase 4 | Apr 28, 2017 | Barzilai Medical Center |
| NCT02569541 | Phase 2/Phase 3 (Phase 3) | Dec 1, 2015 | Cempra Inc |
| NCT02570490 | Phase 3 | Nov 1, 2015 | Cempra Inc |
| NCT01756924 | Phase 2 | Dec 1, 2012 | Cempra Inc |
| NCT01113125 | Phase 3 | Mar 1, 2010 | Aarhus University |
| NCT00948142 | Phase 2 | Aug 1, 2009 | Cempra Inc |
| NCT00718315 | Phase 3 | Apr 1, 2009 | Roche |
| NCT00986856 | Phase 4 | May 1, 2004 | Leo Pharma, Lund University |
Showing 16 of 16 trials
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Organizations
Research & Development (13)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cempra Inc | For profit | 4 | 4 | 2 | 2009 |
| Leo Pharma | For profit | 2 | 2 | 2 | 2004 |
| Aarhus University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| Aceragen | For profit | 1 | 1 | 1 | 2022 |
| Arrevus Inc. | For profit | 1 | 1 | 1 | 2022 |
| Barzilai Medical Center | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Baxis Pharmaceuticals, Inc. | For profit | 1 | 1 | 1 | 2025 |
| Cyberjaya University College of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Lund University | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Red Cross War Memorial Childrens Hospital | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Roche | For profit | 1 | 1 | 1 | 2009 |
| University of Barcelona | Academic/Hospital | 1 | 1 | 1 | 2022 |
| University of Indonesia | Academic/Hospital | 1 | 1 | 1 | 2021 |
13 organizations
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