centella asiatica
Botanicalexperimental
Centella asiatica, commonly known as Indian pennywort, Asiatic pennywort, spadeleaf, coinwort or gotu kola, is a herbaceous, perennial plant in the flowering plant family Apiaceae. It is native to tropical regions of Africa, Asia, Australia, and islands in the western Pacific Ocean. It is consumed as a culinary vegetable and is used in traditional medicine. — Wikipedia
Clinical trial activity
22 trials · 26 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
3
Phase 3
3
Phase 4
8
Earliest trial started Dec 1, 2008 (NCT00709514)
Timeline
Indications
Approved for
Studied for
- Aged · Early Phase 1
- Breast Neoplasms · Phase 4
- Cicatrix · Phase 4
- Cognitive Dysfunction · Early Phase 1
- Diabetes Mellitus · Phase 4
- Diabetes Mellitus, Type 2 · Phase 4
- Diabetic Foot · Phase 4
- Drug Delivery Systems · Phase 2/Phase 3
- General Surgery · Early Phase 1
- Gingival Diseases · Phase 1
- Healthy Volunteers · Early Phase 1
- Hemorrhoids · Phase 4
- Leg Ulcer · Phase 4
- Postoperative Pain · Phase 4
- Pressure Ulcer · Phase 4
- Skin Diseases · Phase 4
- Trial of Labor · Phase 3
- Wound Healing · Early Phase 1
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCentella asiatica ↗
- NCATS6810070TYD ↗
- ChEMBLCHEMBL5095437 ↗
Also known as
- centella asiatica
- dcb-wh1
- gotukola
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06850935 | N/A | Sep 4, 2024 | Hung Kaung University |
| NCT06472791 | N/A | Sep 1, 2024 | National College of Natural Medicine |
| NCT06566508 | Phase 2/Phase 3 (Phase 3) | Nov 20, 2023 | Mansoura University |
| NCT05937529 | N/A | Sep 27, 2023 | L'Oreal, University of Copenhagen |
| NCT05438251 | Phase 4 | Sep 1, 2022 | China Medical University |
| NCT05317442 | Phase 4 | Mar 30, 2022 | Kaohsiung Medical University, Taipei Medical University |
| NCT05271708 | Phase 4 | Jan 5, 2022 | Government of Taiwan |
| NCT05338463 | Phase 4 | Dec 1, 2021 | Cathay General Hospital |
| NCT04962139 | Phase 3 | Aug 10, 2021 | Oneness Biotech Co., Ltd. |
| NCT05322525 | Phase 4 | Jun 23, 2021 | Taipei Medical University, Taipei Veteran General hospital |
| NCT04886882 | Early Phase 1 (Phase 1) | Mar 22, 2021 | Basaksehir Cam & Sakura Şehir Hospital, Istanbul Kent University |
| NCT04945161 | N/A | Mar 2, 2021 | Oneness Biotech Co., Ltd. |
| NCT04669119 | Phase 4 | Dec 31, 2020 | University of Bari |
| NCT03937908 | Early Phase 1 (Phase 1) | Aug 1, 2019 | National Center for Complementary and Integrative Health (NCCIH), Oregon Health and Science University |
| NCT03929250 | Early Phase 1 (Phase 1) | Jul 1, 2019 | Oregon Health and Science University |
| NCT03815305 | Phase 4 | Jul 30, 2018 | University of Indonesia |
| NCT03569930 | Phase 4 | May 1, 2018 | University of Roma La Sapienza |
| NCT07071389 | N/A | Jan 8, 2018 | Lo.Li. Pharma, Ltd. |
| NCT02827305 | Phase 1 | Aug 1, 2015 | Sri Hasanamba Dental College and Hospital |
| NCT05017467 | Early Phase 1 (Phase 1) | Jan 1, 2011 | Istanbul Medipol University, Konya Numune Hospital |
Showing 20 of 22 trials
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Organizations
Research & Development (26)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Oneness Biotech Co., Ltd. | For profit | 2 | 2 | 2 | 2021 |
| Oregon Health and Science University | Academic/Hospital | 2 | 2 | 1 | 2019 |
| Taipei Medical University | Academic/Hospital | 2 | 1 | 1 | 2021 |
| Taipei Veteran General hospital | Government | 2 | 0 | 2 | 2008 |
| Basaksehir Cam & Sakura Şehir Hospital | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Cathay General Hospital | Academic/Hospital | 1 | 1 | 1 | 2021 |
| China Medical University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Government of Taiwan | Government | 1 | 1 | 1 | 2022 |
| Hung Kaung University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Istanbul Kent University | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Istanbul Medipol University | Academic/Hospital | 1 | 0 | 1 | 2011 |
| Kaohsiung Medical University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Konya Numune Hospital | Academic/Hospital | 1 | 1 | 1 | 2011 |
| LG | For profit | 1 | 1 | 1 | 2009 |
| Lo.Li. Pharma, Ltd. | For profit | 1 | 1 | 1 | 2018 |
| L'Oreal | For profit | 1 | 0 | 1 | 2023 |
| Mansoura University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Microbio Co Ltd | For profit | 1 | 1 | 1 | 2008 |
| National Center for Complementary and Integrative Health (NCCIH) | Government | 1 | 0 | 1 | 2019 |
| National College of Natural Medicine | Academic/Hospital | 1 | 1 | 1 | 2024 |
26 organizations
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