surfactant
Recombinant proteinexperimental
Surfactants are chemical compounds that decrease the surface tension or interfacial tension between two liquids, a liquid and a gas, or a liquid and a solid. The word surfactant is a blend of "surface-active agent", coined in 1950. As they consist of a water-repellent and a water-attracting part, they are emulsifiers, enabling water and oil to mix. They can also form foam, and facilitate the detachment of dirt. — Wikipedia
Clinical trial activity
35 trials · 63 clinical orgs · 0 marketing orgs
Phase 1
8
Phase 2
15
Phase 3
8
Phase 4
8
Earliest trial started Jan 1, 1986 (NCT00000570)
Timeline
Indications
Approved for
Studied for
- Bronchiolitis, Viral · Phase 3
- Bronchoalveolar Lavage Fluid · Phase 4
- Bronchopulmonary Dysplasia · Phase 3
- Burns · Phase 1/Phase 2
- Cystic Fibrosis · Phase 1/Phase 2
- Cytokines · Phase 4
- Dentist-Patient Relations · Phase 1
- Diabetic Foot · Phase 2
- Infant, Newborn · Phase 3
- Infant, Newborn, Diseases · Phase 3
- Infant, Premature · Phase 4
- Infant, Premature, Diseases · Phase 4
- Infant, Small for Gestational Age · Phase 3
- Infections · Phase 2
- Lung Diseases · Phase 4
- Lung Transplantation · Phase 2/Phase 3
- Meconium Aspiration Syndrome · Phase 4
- Neonatology · Phase 4
- Perinatal Death · Phase 4
- Premature Birth · Phase 4
- Primary Graft Dysfunction · Phase 2/Phase 3
- Respiratory Distress Syndrome · Phase 4
- Respiratory Distress Syndrome, Newborn · Phase 4
- Retinopathy of Prematurity · Phase 3
- Sjogren's Syndrome · Phase 2
- Skin and Connective Tissue Diseases · Phase 1
- Surface-Active Agents · Phase 3
- Vitamin A · Phase 3
- Xerostomia · Phase 2
Mechanism of action
- Unspecified targetSurfactant
surfactant
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSurfactant ↗
Also known as
- surfactant
- surfactant
- surfactants
- surfactants
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06554522 | Phase 4 | Oct 1, 2024 | Aga Khan University, Indiana University, Open Philanthropy Project |
| NCT05898633 | Phase 1 | Dec 31, 2023 | Medical Research Council, University of London |
| NCT06074380 | Phase 4 | Nov 1, 2023 | University of Chicago |
| NCT05714865 | Phase 4 | Jun 25, 2023 | BLES Biochemicals Inc., Indiana University |
| NCT05534685 | N/A | Sep 20, 2022 | Government of Mexico, Instituto Mexicano del Seguro Social |
| NCT05000983 | Phase 1/Phase 2 (Phase 2) | Oct 20, 2021 | Medline Industries, University of Manitoba |
| NCT04893863 | Phase 1/Phase 2 (Phase 2) | Oct 1, 2021 | University of Manitoba |
| NCT04984057 | N/A | Aug 1, 2021 | Chongqing Medical University, People's Liberation Army of China |
| NCT04847375 | N/A | Apr 20, 2021 | Shahid Beheshti University of Medical Sciences |
| NCT04545866 | Phase 3 | Dec 31, 2020 | National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), University of Alabama, Birmingham |
| NCT03969992 | Phase 2 | Aug 1, 2019 | Aerogen |
| NCT03846960 | N/A | Apr 1, 2019 | Emek Medical Center, Technion University |
| NCT03959384 | Phase 3 | Jan 9, 2019 | University of Verona |
| NCT03217162 | N/A | Aug 1, 2017 | People's Liberation Army of China |
| NCT02985437 | Phase 1 | Nov 1, 2016 | European Research Council, University of Bremen |
| NCT02825953 | N/A | Jan 1, 2016 | Yuzuncu Yıl University |
| NCT02294630 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2014 | Wayne State University |
| NCT02337192 | Phase 1 | Jan 1, 2014 | University of Sao Paulo |
| NCT02091596 | Phase 2 | Oct 31, 2013 | Arkios BioDevelopment International, PluroGen Therapeutics |
| NCT02041546 | Phase 4 | Sep 1, 2013 | Zekai Tahir Burak Hospital |
Showing 20 of 35 trials
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Organizations
Research & Development (63)
63 organizations
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