amniotic membrane
Biologicalexperimental
The amnion is a membrane that closely covers human and various other embryos when they first form. It fills with amniotic fluid, which causes the amnion to expand and become the amniotic sac that provides a protective environment for the developing embryo. The amnion, along with the chorion, the yolk sac and the allantois protect the embryo. In birds, reptiles and monotremes, the protective sac is enclosed in a shell. In marsupials and placental mammals, it is enclosed in a uterus. — Wikipedia
Clinical trial activity
24 trials · 28 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
7
Phase 3
3
Phase 4
2
Earliest trial started Oct 1, 2005 (NCT00238862)
Timeline
Indications
Approved for
Studied for
- Burns · Phase 2/Phase 3
- Corneal Diseases · Phase 2
- Corneal Injuries · Phase 1/Phase 2
- Corneal Ulcer · Phase 2
- Cystitis, Interstitial · Phase 3
- Dermatology · Phase 4
- Esophageal Neoplasms · Phase 1/Phase 2
- Fasciitis, Plantar · Phase 2/Phase 3
- Glaucoma · Phase 1
- Hyperopia · Phase 1/Phase 2
- Intervertebral Disc Displacement · Phase 4
- Keratitis · Phase 2
- Myopia · Phase 1/Phase 2
- Prostatic Neoplasms · Phase 2
- Pterygium · Phase 1/Phase 2
- Stem Cells · Phase 1
- Wounds and Injuries · Phase 1
Mechanism of action
- SkinTissue restoration
Skin tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAmnion ↗
Also known as
- amniotic membrane
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07300137 | N/A | Sep 20, 2025 | Patel Hospital Pvt. Ltd. |
| NCT06731803 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2025 | Daiichi Sankyo, IKF Klinische Krebsforschung GmbH am Krankenhaus Nordwest, Institut für Klinische Krebsforschung IKF GmbH |
| NCT06096597 | Phase 3 | Jan 31, 2024 | Case Western Reserve University |
| NCT06172218 | N/A | Nov 22, 2023 | North Park Podiatry |
| NCT07219004 | N/A | Mar 3, 2023 | Tides Medical |
| NCT05320419 | N/A | Jan 1, 2023 | Shin Kong Wu Ho-Su Memorial Hospital |
| NCT05172349 | Phase 2 | Apr 30, 2022 | TBF Genie Tissulaire |
| NCT05250583 | Phase 2 | Jun 29, 2020 | TBF Genie Tissulaire |
| NCT03912116 | N/A | Apr 9, 2019 | Tissue Tech Inc. |
| NCT04030754 | Phase 2/Phase 3 (Phase 3) | Jan 24, 2019 | King Edward Medical University |
| NCT03205436 | N/A | May 1, 2017 | Organogenesis, SerenaGroup, Inc. |
| NCT02645591 | Phase 2 | Nov 30, 2016 | MiMedx Group, Inc., University of Texas at Houston |
| NCT02521402 | Phase 4 | Aug 31, 2015 | Golla Center for Plastic Surgery |
| NCT02506452 | N/A | Jun 30, 2015 | Alliqua BioMedical |
| NCT02427191 | Phase 2/Phase 3 (Phase 3) | Mar 31, 2015 | MedStar Cardiovascular Research Network, MiMedx Group, Inc. |
| NCT02209051 | N/A | Jul 31, 2014 | Integra LifeSciences Corporation |
| NCT02746848 | Phase 1/Phase 2 (Phase 2) | Jun 30, 2014 | Royan Institute |
| NCT01921569 | N/A | Jun 30, 2013 | MiMedx Group, Inc. |
| NCT02148016 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2012 | Sun Yat-Sen University |
| NCT01824381 | Phase 1 | Jul 31, 2012 | MurciaSalud, Public Health Service, Murcia, Red de Terapia Celular, Universidad de Murcia |
Showing 20 of 24 trials
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Organizations
Research & Development (28)
28 organizations
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