Roche
Also known as: Carmot Therapeutics, Inc., a Member of the Roche Group | CHD de Vendee LA ROCHE SUR YON France | CHD La Roche sur Yon | CHD of La Roche/Yon | CHD Vendee | CHD VENDEE - La Roche sur Yon | F. Hoffmann-La Roche | F. Hoffmann-La Roche Ltd; German CLL Study Group (GCLLSG); Dana-Farber Cancer Institute | Genentech, Inc. | GENENTECH INC | HLR | Hofffmann-La Roche | HOFFMAN-LA ROCHE | Hoffmann-LaRoche | Hoffmann-La Roche | HOFFMANN LA ROCHE | HOFFMANN-LA ROCHE | Hoffmann-La Roche, 973-235-5000 | Hoffmann-La Roche Inc. | nv Roche sa | ROCHE | Roche, Austria | Roche BV Netherlands | Roche Chugai | Roche, Copenhagen | Roche Diagnostics | Roche Diagnostics International AG | Roche Farma, S.A | Roche for trial and Saquinavir,and Abbott for Kaletra | Roche Foundation of Anemia Research (RoFAR, Switzerland) | Roche-Genentech | Roche/Genentech Inc. | Roche/Genetech | Roche Global Development | Roche (Grenzach-Wyhlen, Germany) | Roche Korea co.,Ltd. | Roche Molecular Systems, Inc | ROCHE PALO | Roche Pharma AG | Roche Pharma AG, 79639 Grenazch Wyhlen, Germany | Roche Pharma, Italy | Roche Products (India) Pvt. Ltd. | Roche Products Pty Limited | Roche - Prof. Dr. Jens Huober et al. | Roche S.p.a | Roche SpA | Roche Therapeutics Ltd
Highest phase reached
Phase 4
First clinical trial
Jul 1, 1992First marketed drug
Jul 15, 1941First NDA
Jul 15, 1941Last known activity
Mar 31, 2026
Timeline
1890s
- Jan 1, 1896
Roche— Founded
1970s
- Jan 1, 1975
Medi-Physics— Acquired
1980s
- Jan 1, 1982
Biomedical Reference Laboratories— Acquired
- Dec 21, 1984
lidocaine— Marketing Organization
1990s
- Jan 1, 1994
Syntex— Acquired
- Jan 1, 1997
Boehringer-Mannheim— Acquired
- Apr 23, 1999
orlistat— NDA Organization
2000s
- Jan 1, 2005
Glycart— Acquired
- Jan 1, 2007
454 Life Sciences— Acquired
- Jan 1, 2007
Nimblegen— Acquired
- Jan 1, 2007
Spring BioScience Corp— Acquired
- Jan 1, 2007
Therapeutic Human Polyclonals— Acquired
- Jan 1, 2008
Memory Pharmaceuticals— Acquired
- Jan 1, 2008
Piramed— Acquired
- Jan 1, 2009
Genentech— Acquired - Jan 1, 2009
Ventana Medical Systems— Acquired
2010s
- Jan 1, 2010
BioImagene— Acquired
- Jan 1, 2010
Marcadia Biotech— Acquired
- Jan 1, 2010
Medingo Medical Solutions— Acquired
- Jan 1, 2011
Anadys Pharmaceuticals— Acquired
- Jan 1, 2011
MTM Laboratories AG— Acquired
- Jan 1, 2011
PVT Probenvertiltechnik GmbH— Acquired
- Jan 1, 2014
Ariosa Diagnostics— Acquired
- Jan 1, 2014
Bina Technologies— Acquired
- Jan 1, 2014
Chugai— Acquired
- Jan 1, 2014
Constitution Medical Inc— Acquired
- Jan 1, 2014
Genia Technologies, Inc— Acquired
- Jan 1, 2014
InterMune— Acquired
- Jan 1, 2014
Iquum— Acquired
- Jan 1, 2014
Seragon Pharmaceuticals— Acquired
- Aug 4, 2014
Santaris Pharma A/S— Acquired
- Jan 1, 2015
Adheron Therapeutics— Acquired
- Jan 1, 2015
Foundation Medicine— Acquired
- Jan 1, 2015
GeneWeave— Acquired
- Jan 1, 2015
Kapa Biosystems— Acquired
- Jan 1, 2015
Trophos— Acquired
- Dec 1, 2016
Tensha Therapeutics— Acquired
- Jan 1, 2017
Forsight Vision4— Acquired
- Feb 1, 2018
Ignyta, Inc.— Acquired
- Feb 14, 2019
Spark Therapeutics— Acquired
- Nov 15, 2019
Promedior, Inc.— Acquired
2020s
- Aug 7, 2020
risdiplam— NDA Secondary Org
- Sep 22, 2020
Inflazome— Acquired
- Mar 15, 2021
GenMark Diagnostics— Acquired
- Dec 4, 2023
Carmot Therapeutics, Inc.— Acquired
- Nov 26, 2024
Poseida Therapeutics, Inc.— Acquired
- Oct 1, 2025
89bio Ltd.— Acquired
Drugs by trial phase (898 distinct, 3945 trials)
Phase 4 (42 own, 115 via acquisition)
Phase 3 (71 own, 102 via acquisition)
Phase 2 (121 own, 178 via acquisition)
Phase 1 (128 own, 128 via acquisition)
Indications
Approved for
- Acute Pain
- Alcohol Withdrawal Delirium
- Anemia
- Anemia, Iron-Deficiency
- Anemia, Pernicious
- Angina Pectoris, Variant
- Angina, Stable
- Anxiety
- Anxiety Disorders
- Arthritis, Gouty
- Arthritis, Juvenile
- Arthritis, Rheumatoid
- Asthma
- Back Pain
- Bone Diseases, Infectious
- Bone Neoplasms
- Breast Neoplasms
- Bronchitis, Chronic
- Bursitis
- Carcinoma, Non-Small-Cell Lung
- Cestode Infections
- Colonic Neoplasms
- Colorectal Neoplasms
- Coronary Artery Disease
- Cytomegalovirus Infections
- Cytomegalovirus Retinitis
- Depression
- Diabetes Mellitus, Type 2
- Diarrhea
- Drug Overdose
- Dysentery, Bacillary
- Dysmenorrhea
- Edema
- Endocarditis, Bacterial
- Enterocolitis
- Epilepsy
- Fatigue Syndrome, Chronic
- Folic Acid Deficiency
- Gonorrhea
- Gout
- Heart Failure
- HIV Infections
- Hypertension
- Hypoprothrombinemias
- Infections
- Influenza A virus
- Influenza, Human
- Intraabdominal Infections
- Irritable Bowel Syndrome
- Keratitis, Herpetic
- Kidney Diseases
- Kidney Failure, Chronic
- Lyme Disease
- Malaria
- Melanoma
- Meningitis
- Migraine Disorders
- Multiple Sclerosis, Chronic Progressive
- Multiple Sclerosis, Relapsing-Remitting
- Muscle Spasticity
- Narcotic-Related Disorders
- Nephrotic Syndrome
- Obesity
- Osteoarthritis
- Osteoporosis
- Osteoporosis, Postmenopausal
- Otitis Media
- Pain
- Panic Disorder
- Parkinson Disease
- Pelvic Inflammatory Disease
- Peptic Ulcer
- Pneumonia, Pneumocystis
- Post-Exposure Prophylaxis
- Postoperative Nausea and Vomiting
- Postoperative Pain
- Protoporphyria, Erythropoietic
- Pruritus
- Psoriasis
- Psychomotor Agitation
- Psychotic Disorders
- Renal Insufficiency, Chronic
- Respiratory Insufficiency
- Respiratory Tract Infections
- Rhinitis, Allergic, Seasonal
- Seizures
- Sepsis
- Sleep Initiation and Maintenance Disorders
- Spasm
- Spasms, Infantile
- Spondylitis, Ankylosing
- Staphylococcal Skin Infections
- Stomach Ulcer
- Stroke
- Tendinopathy
- Urinary Tract Infections
- Vitamin B Deficiency
- Vitamin K Deficiency
- Vitamin K Deficiency Bleeding
- Vomiting
Studied for
- Acquired Immunodeficiency Syndrome
- Acute Coronary Syndrome
- Adenocarcinoma
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenocarcinoma, Clear Cell
- Adenocarcinoma of Lung
- Aggression
- AIDS-Associated Nephropathy
- AIDS-Related Complex
- Alzheimer Disease
- Amyotrophic Lateral Sclerosis
- Anemia
- Anemia, Hemolytic
- Anemia, Hemolytic, Autoimmune
- Anemia, Iron-Deficiency
- Angelman Syndrome
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Anus Neoplasms
- Anxiety Disorders
- Arteritis
- Arthritis
- Arthritis, Juvenile
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Atherosclerosis
- Atrophy
- Autism Spectrum Disorder
- Autistic Disorder
- Azotemia
- Bacterial Infections
- Basal Cell Carcinoma
- Basal Cell Nevus Syndrome
- Behcet Syndrome
- beta-Thalassemia
- Biliary Tract Neoplasms
- Bone Diseases
- Bone Diseases, Metabolic
- Bone Neoplasms
- Brain Neoplasms
- Breast Diseases
- Breast Neoplasms
- Burkitt Lymphoma
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Hepatocellular
- Carcinoma in Situ
- Carcinoma, Lobular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Ovarian Epithelial
- Carcinoma, Renal Cell
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiotoxicity
- Cardiovascular Diseases
- Castleman Disease
- Celiac Disease
- Central Nervous System Neoplasms
- Cervical Intraepithelial Neoplasia
- Child Development Disorders, Pervasive
- Cholangiocarcinoma
- Choroidal Neovascularization
- Choroideremia
- Cognition Disorders
- Cognitive Dysfunction
- Coinfection
- Colitis
- Colitis, Ulcerative
- Colonic Neoplasms
- Colorectal Neoplasms
- Communicable Diseases
- Compulsive Personality Disorder
- Congenital Abnormalities
- Coronary Artery Disease
- Coronary Disease
- Coronavirus Infections
- Crohn Disease
- Cystic Fibrosis
- Cytomegalovirus Infections
- Cytomegalovirus Retinitis
- Deficiency Diseases
- Delayed Graft Function
- Dementia
- Dengue
- Depression
- Depressive Disorder
- Depressive Disorder, Treatment-Resistant
- Dermatitis
- Dermatitis, Atopic
- Developmental Disabilities
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Foot
- Diabetic Nephropathies
- Diabetic Neuropathies
- Diabetic Retinopathy
- Digestive System Diseases
- Disease
Marketed drugs (102)
Subsidiaries (43 direct, 46 total across the full acquisition tree)
- 454 Life Sciences
- 89bio Ltd.
- Adheron Therapeutics
- Anadys Pharmaceuticals
- Ariosa Diagnostics
- Bina Technologies
- BioImagene
- Biomedical Reference Laboratories
- Boehringer-Mannheim
- Carmot Therapeutics, Inc.
- Chugai
- Constitution Medical Inc
- Forsight Vision4
- Foundation Medicine
- Genentech
- GeneWeave
- Genia Technologies, Inc
- GenMark Diagnostics
- Glycart
- Ignyta, Inc.
- Inflazome
- InterMune
- Iquum
- Kapa Biosystems
- Marcadia Biotech
- Medingo Medical Solutions
- Medi-Physics
- Memory Pharmaceuticals
- MTM Laboratories AG
- Nimblegen
- Piramed
- Poseida Therapeutics, Inc.
- Promedior, Inc.
- PVT Probenvertiltechnik GmbH
- Santaris Pharma A/S
- Seragon Pharmaceuticals
- Spark Therapeutics
- Spring BioScience Corp
- Syntex
- Tensha Therapeutics
- Therapeutic Human Polyclonals
- Trophos
- Ventana Medical Systems
- Lexent Bio L2
- Marnac, Inc. L2
- Tanox L2
Recent trials (50)
- NCT04256265Study directorN/A—
- NCT07287150Lead sponsorPhase 2Mar 31, 2026
- NCT07287150OfficialPhase 2Mar 31, 2026
- NCT07172022OfficialPhase 2Mar 16, 2026
- NCT07172022Lead sponsorPhase 2Mar 16, 2026
- NCT07234942Lead sponsorPhase 1Jan 31, 2026
- NCT07234942OfficialPhase 1Jan 31, 2026
- NCT07282574Lead sponsorPhase 2Jan 30, 2026
- NCT07282574OfficialPhase 2Jan 30, 2026
- NCT07271693Lead sponsorPhase 1Jan 16, 2026
- NCT07271693OfficialPhase 1Jan 16, 2026
- NCT07174310OfficialPhase 3Dec 31, 2025
- NCT07174310Lead sponsorPhase 3Dec 31, 2025
- NCT07246941Lead sponsorPhase 1Nov 19, 2025
- NCT07246941OfficialPhase 1Nov 19, 2025
Details
- Founded
- Basel, CH Jan 1, 1896
- First NDA
- Jul 15, 1941
- Last known activity
- Mar 31, 2026
Designations held
- Orphan drug
- Fast track
- Priority review
- Breakthrough therapy
- Accelerated approval