bone autograft
Cell therapyexperimental
Clinical trial activity
133 trials · 131 clinical orgs · 0 marketing orgs
Phase 1
34
Phase 2
99
Phase 3
35
Phase 4
3
Earliest trial started Apr 1, 1988 (NCT00002461)
Timeline
Indications
Approved for
Studied for
- Alveolar Bone Loss · Phase 4
- Alveolar Ridge Augmentation · Phase 2
- Arthropathy, Neurogenic · Phase 2/Phase 3
- Bone Diseases · Phase 2/Phase 3
- Brain Injuries, Traumatic · Phase 1
- Brain Neoplasms · Phase 3
- Breast Neoplasms · Phase 3
- Burns, Chemical · Phase 2
- Carcinoma, Hepatocellular · Phase 2
- Cardiomyopathies · Phase 1/Phase 2
- Central Nervous System Neoplasms · Phase 3
- Chronic Limb-Threatening Ischemia · Phase 2/Phase 3
- Chronic Periodontitis · Phase 4
- Colorectal Neoplasms · Phase 1/Phase 2
- Diabetes Mellitus, Type 2 · Phase 2/Phase 3
- Diabetic Foot · Phase 1/Phase 2
- Fallopian Tube Neoplasms · Phase 1
- Hamartoma · Phase 1
- Head and Neck Neoplasms · Phase 2
- Inflammatory Bowel Diseases · Phase 1
- Intervertebral Disc Degeneration · Phase 2/Phase 3
- Kidney Failure, Chronic · Phase 1/Phase 2
- Kidney Neoplasms · Phase 2
- Knee · Phase 1/Phase 2
- Leukemia · Phase 3
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 2
- Leukemia, Myeloid, Acute · Phase 2
- Liver Cirrhosis · Phase 1/Phase 2
- Liver Neoplasms · Phase 2
- Low Back Pain · Phase 2/Phase 3
- Lung Neoplasms · Phase 3
- Lymphoma · Phase 3
- Lymphoma, Large B-Cell, Diffuse · Phase 3
- Multiple Myeloma · Phase 3
- Myelodysplastic-Myeloproliferative Diseases · Phase 2
- Myelodysplastic Syndromes · Phase 2
- Myeloproliferative Disorders · Phase 1/Phase 2
- Myocardial Infarction · Phase 1/Phase 2
- Myocardial Ischemia · Phase 1
- Neoplasms · Phase 3
- Neuroblastoma · Phase 3
- Neutropenia · Phase 3
- Osteoarthritis · Phase 2
- Osteoarthritis, Knee · Phase 4
- Ovarian Neoplasms · Phase 3
- Pancreatic Neoplasms · Phase 1/Phase 2
- Precancerous Conditions · Phase 1/Phase 2
- Radiculopathy · Phase 2/Phase 3
- Retinoblastoma · Phase 3
- Sacroiliac Joint · Phase 2/Phase 3
- Sarcoma · Phase 2
- Spinal Cord Injuries · Phase 1/Phase 2
- Spinal Diseases · Phase 2/Phase 3
- Spinal Stenosis · Phase 2/Phase 3
- Teratoma · Phase 2
- Testicular Neoplasms · Phase 3
- Tooth · Phase 3
Mechanism of action
- BloodTissue restoration
Blood tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- aulogous bone
- autogenous bone
- autologous bone
- autologous bone marrow
- bone autograft
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07242729 | N/A | Feb 1, 2025 | Federal University of Sao Paulo |
| NCT05517434 | Phase 2/Phase 3 (Phase 3) | Oct 31, 2022 | The Cleveland Clinic, University of Toronto |
| NCT05507099 | Phase 2 | Aug 8, 2022 | Dr. G. Karmy Medicine Professional Corporation |
| NCT04475341 | N/A | Sep 1, 2020 | University of Amsterdam |
| NCT04205656 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2020 | Department of Defense, United States Navy |
| NCT03912454 | N/A | Apr 30, 2019 | Bone and Joint Clinic of Baton Rouge |
| NCT04559295 | Phase 2/Phase 3 (Phase 3) | Nov 21, 2018 | Stem Cures |
| NCT03340818 | N/A | Jul 30, 2018 | APM Spine and Sports Physicians, Jordan Young Institute, Stanford University |
| NCT03876795 | Phase 3 | May 9, 2018 | University of Bologna |
| NCT02779374 | N/A | Jul 31, 2016 | South Valley University |
| NCT03110666 | Phase 4 | Jul 25, 2016 | University of Bologna |
| NCT02443077 | Phase 3 | Jul 6, 2016 | National Cancer Institute (NCI) |
| NCT02702960 | Phase 2 | Mar 1, 2016 | Fibrolamellar Cancer Foundation, Johns Hopkins University |
| NCT03110679 | Phase 4 | Feb 18, 2016 | University of Bologna |
| NCT02529839 | N/A | Oct 1, 2015 | Hebrew University |
| NCT02325843 | Phase 2 | Jul 31, 2015 | Sun Yat-Sen University, Xiamen University |
| NCT02240342 | N/A | Sep 30, 2014 | University of Valencia |
| NCT02011295 | N/A | Jan 29, 2014 | Duke University |
| NCT01536106 | Phase 1/Phase 2 (Phase 2) | Dec 31, 2013 | Care Hospital, Hyderabad, Fortis Escorts Heart Institute and Research Centre, TotipotentRX |
| NCT02059681 | Phase 1 | Dec 31, 2013 | Azienda Ospedaliera San Gerardo di Monza, Azienda Sanitaria Ospedaliera Molinette S. Giovanni Battista, Centro Cardiologico Monzino IRCCS, University of Turin |
Showing 20 of 133 trials
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Organizations
Research & Development (131)
131 organizations
Page 1 / 7