hemoglobin
Biologicalexperimental
Hemoglobin is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12 to 20 grams of hemoglobin in every 100 mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin. — Wikipedia
Clinical trial activity
7 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
2
Phase 3
2
Phase 4
1
Earliest trial started Mar 1, 2001 (NCT00021502)
Timeline
2000s
- Jan 1, 2001
Earliest Phase 3 Sponsor(trial)
Indications
Approved for
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaHemoglobin ↗
- WikipediaBlood substitute ↗
Also known as
- hemoglobin
- hemoglobin
- polyheme
- polyheme
- pyridoxalated hemoglobin polyoxyethylene conjugate
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06427421 | N/A | Jun 30, 2024 | Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France |
| NCT05440968 | N/A | Jun 30, 2022 | Bay Area Retina Associates |
| NCT04506125 | N/A | Jan 15, 2021 | University of Western Brittany |
| NCT01350102 | Phase 4 | Feb 1, 2012 | Milton S. Hershey Medical Center, Pennsylvania State University |
| NCT01195025 | N/A | Aug 1, 2010 | Linkoping University |
| NCT00076648 | Phase 3 | Jan 28, 2004 | Northfield Laboratories |
| NCT00021502 | Phase 3 | Mar 1, 2001 | Apex Bioscience |
Showing 7 of 7 trials
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Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Apex Bioscience | For profit | 1 | 1 | 1 | 2001 |
| Assistance Publique - Hôpitaux de Paris | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Bay Area Retina Associates | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Institut National de la Santé Et de la Recherche Médicale, France | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Linkoping University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| Milton S. Hershey Medical Center | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Northfield Laboratories | For profit | 1 | 1 | 1 | 2004 |
| Pennsylvania State University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| University of Western Brittany | Academic/Hospital | 1 | 1 | 1 | 2021 |
9 organizations
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