CDEK
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peripheral blood lymphocytes

Cell therapyexperimental

Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. — Wikipedia

Clinical trial activity

75 trials · 63 clinical orgs · 0 marketing orgs

Phase 1
34
Phase 2
49
Phase 3
3
Phase 4
0

Earliest trial started Nov 1, 1995 (NCT00002718)

Timeline

1990s

  1. Jan 1, 1995

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 1998

    Earliest Phase 1 Sponsor(trial)

2000s

  1. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

  • LymphocytesSupplementation

    supplementation - lymphocytes

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • autologous pbmc
  • autologous pbmcs
  • autologous peripheral blood lymphocytes
  • autologous peripheral blood mononuclear cells
  • autologous peripheral-blood mononuclear cells including a minimum of 50 million autologous cd54+ cells activated with prostatic acid phosphatase granulocyte-macrophage colony-stimulating factor
  • in vitro-treated peripheral blood lymphocyte
  • in vitro-treated peripheral blood stem cell
  • peripheral blood
  • peripheral blood cells
  • peripheral blood derived mononuclear cells
  • peripheral blood lymphocyte
  • peripheral blood lymphocytes
  • peripheral blood mononuclear cell
  • peripheral blood mononuclear cells
  • peripheral mononuclear cell

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07270978Phase 1Dec 31, 2025University of Virginia
NCT06389305N/AJun 1, 2024Government of China
NCT05421364N/ADec 9, 2023Nadezhda Women's Health Hospital
NCT05775198N/AMar 1, 2023Nadezhda Women's Health Hospital
NCT04645485Phase 1May 12, 2020Abu Dhabi Stem Cells Center
NCT04473170Phase 1/Phase 2 (Phase 2)Apr 4, 2020Abu Dhabi Stem Cells Center
NCT03771222Phase 2Jan 31, 2019People's Liberation Army of China
NCT03825146Phase 1Jan 4, 2019Lai Corporation Pty. Ltd., Panacee Hospital Rama 2
NCT03267797Phase 2Dec 7, 2018Tabriz Medical University
NCT02465268Phase 2Aug 1, 2016National Cancer Institute (NCI), University of Florida
NCT02033616Phase 2Jul 1, 2016Caladrius Biosciences
NCT02743351Phase 1/Phase 2 (Phase 2)Jun 1, 2016Fate Therapeutics
NCT02655458Phase 1Jan 1, 2016Bristol-Myers Squibb, Icahn School of Medicine at Mount Sinai
NCT03101163Phase 2Dec 1, 2015KLSMC Stem Cells, Inc.
NCT02252055Phase 1/Phase 2 (Phase 2)Mar 1, 2015University of Nantes, University of Regensburg
NCT01875653Phase 3Oct 1, 2014Caladrius Biosciences
NCT02145923Phase 1/Phase 2 (Phase 2)May 1, 2014Burnasyan Federal Medical Biophysical Center
NCT02315235N/AMay 1, 2014Seoul National University
NCT01833585Phase 3Apr 1, 2013Mahidol University
NCT01793025Phase 1Sep 1, 2012University of Montreal
Showing 20 of 75 trials
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Organizations

Research & Development (63)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government32741995
University of WashingtonAcademic/Hospital8811998
National Heart, Lung, and Blood Institute (NHLBI)Government4412001
Northwestern UniversityAcademic/Hospital3321999
Abu Dhabi Stem Cells CenterAcademic/Hospital2222020
Baylor UniversityAcademic/Hospital2211999
Caladrius BiosciencesFor profit2222014
Case Western Reserve UniversityAcademic/Hospital2211999
Johns Hopkins UniversityAcademic/Hospital2221998
Kobe UniversityAcademic/Hospital2012003
Nadezhda Women's Health HospitalAcademic/Hospital2212023
National Institute of Allergy and Infectious Diseases (NIAID)Government2121999
National Institutes of Health (NIH)Government2122004
Rutgers UniversityAcademic/Hospital2011999
University of California, San FranciscoAcademic/Hospital2122001
University of MarylandAcademic/Hospital2211998
University of MinnesotaAcademic/Hospital2212000
University of TuebingenAcademic/Hospital2212005
Beike BiotechFor profit1112009
Bristol-Myers SquibbFor profit1012016
63 organizations
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