autologous bone marrow derived mesenchymal cells
Cell therapyexperimental
Clinical trial activity
68 trials · 93 clinical orgs · 0 marketing orgs
Phase 1
30
Phase 2
38
Phase 3
9
Phase 4
2
Earliest trial started Apr 1, 2005 (NCT00271947)
Timeline
Indications
Approved for
Studied for
- Acetabularia · Phase 3
- Amyotrophic Lateral Sclerosis · Phase 1/Phase 2
- Anemia, Sickle Cell · Phase 1
- Angina Pectoris · Phase 2
- Autism Spectrum Disorder · Phase 2
- Back Pain · Phase 2
- Behcet Syndrome · Phase 1
- Biliary Atresia · Phase 1
- Bone Marrow Cells · Phase 3
- Brain Injuries, Traumatic · Phase 2
- Cartilage, Articular · Phase 3
- Cartilage Diseases · Phase 1/Phase 2
- Cerebral Palsy · Phase 2
- Chronic Limb-Threatening Ischemia · Phase 1
- Colitis, Ulcerative · Phase 1
- Colonic Pouches · Phase 1
- Crohn Disease · Phase 2
- Diabetes Mellitus, Type 1 · Phase 1
- Diabetes Mellitus, Type 2 · Phase 2
- Diabetic Foot · Phase 1
- Femoracetabular Impingement · Phase 3
- Fistula · Phase 1
- Fractures, Bone · Phase 1/Phase 2
- Frailty · Phase 1/Phase 2
- Gangrene · Phase 1
- Heart Diseases · Phase 1/Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 2
- Hodgkin Disease · Phase 2
- Ileum · Phase 1
- Inflammatory Bowel Diseases · Phase 1
- Intervertebral Disc Degeneration · Phase 2/Phase 3
- Ischemia · Phase 1
- Joint Diseases · Phase 1/Phase 2
- Knee Injuries · Phase 1/Phase 2
- Leg Ulcer · Phase 1
- Leukemia · Phase 1
- Leukemia, Myeloid, Acute · Phase 3
- Liver Cirrhosis · Phase 3
- Liver Cirrhosis, Alcoholic · Phase 1
- Liver Cirrhosis, Biliary · Phase 2
- Liver Transplantation · Phase 2/Phase 3
- Lymphoma, B-Cell · Phase 2
- Macular Degeneration · Phase 1
- Mesenchymal Stem Cells · Phase 4
- Multiple Myeloma · Phase 2
- Multiple Sclerosis · Phase 2
- Multiple System Atrophy · Phase 1
- Myelodysplastic Syndromes · Phase 3
- Myocardial Infarction · Phase 2/Phase 3
- Myocardial Ischemia · Phase 2
- Osteoarthritis · Phase 3
- Osteoarthritis, Knee · Phase 3
- Ovarian Diseases · Phase 3
- Peripheral Vascular Diseases · Phase 1
- Pouchitis · Phase 1
- Primary Ovarian Insufficiency · Phase 1
- Proctitis · Phase 1/Phase 2
- Pseudarthrosis · Phase 1/Phase 2
- Rectal Fistula · Phase 1
- Respiratory Distress Syndrome · Phase 2
- Retinal Degeneration · Phase 1
- Retinitis · Phase 1
- Retinitis Pigmentosa · Phase 1
- Rheumatic Diseases · Phase 1/Phase 2
- Spinal Cord Injuries · Phase 1/Phase 2
- Stargardt Disease · Phase 1
- Waldenstrom Macroglobulinemia · Phase 4
- Xerostomia · Phase 2
Mechanism of action
- Unspecified targetTissue restoration
tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- autologous bone marrow derived endothelial cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06961383 | Phase 2 | Oct 1, 2025 | NeuroGenesis Ltd. |
| NCT06800404 | Phase 2 | Jun 30, 2025 | Hope Biosciences |
| NCT06963866 | Phase 2 | May 1, 2025 | Xuzhou Medical University |
| NCT06925607 | Phase 1 | Apr 30, 2025 | Government of China |
| NCT06438809 | Phase 1/Phase 2 (Phase 2) | May 24, 2024 | Government of China |
| NCT06365671 | Phase 2 | Apr 16, 2024 | Jiao Tong University |
| NCT06429241 | Phase 1 | Apr 8, 2024 | Government of China, Soochow University |
| NCT06381830 | Phase 2 | Jan 1, 2024 | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd, Soochow University |
| NCT05951777 | Phase 2 | Dec 31, 2023 | Hope Biosciences, University of Texas at Houston |
| NCT05983991 | N/A | Dec 7, 2023 | University of Toulouse |
| NCT06149832 | Phase 4 | Nov 30, 2023 | People's Liberation Army of China |
| NCT05711849 | Phase 2 | Sep 1, 2023 | Barts & The London NHS Trust |
| NCT06003101 | Phase 3 | Aug 30, 2023 | Harvard University |
| NCT06030648 | Phase 1 | Aug 28, 2023 | University of Minnesota |
| NCT05694325 | N/A | Mar 31, 2023 | Gruppo Italiano Malattie EMatologiche dell'Adulto |
| NCT05284604 | Phase 1/Phase 2 (Phase 2) | Jan 2, 2023 | Baylor University, Department of Veteran Affairs |
| NCT05985785 | N/A | Jul 19, 2022 | Rush University |
| NCT05578508 | Phase 1 | Apr 30, 2022 | Case Western Reserve University, The Cleveland Clinic |
| NCT05748756 | N/A | Jan 19, 2022 | Alexandria University |
| NCT05307536 | Phase 2 | Dec 26, 2021 | Vinmec International Hospital |
Showing 20 of 68 trials
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Organizations
Research & Development (93)
93 organizations
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