allogeneic adipose derived mesenchymal stem cell
Cell therapyexperimental
Clinical trial activity
336 trials · 368 clinical orgs · 0 marketing orgs
Phase 1
193
Phase 2
197
Phase 3
30
Phase 4
2
Earliest trial started Oct 1, 2001 (NCT00546988)
Timeline
Indications
Approved for
Studied for
- Acute Kidney Injury · Phase 1/Phase 2
- Adipose Tissue · Phase 1/Phase 2
- Adult · Phase 1/Phase 2
- Aging · Phase 1
- Alveolar Ridge Augmentation · Early Phase 1
- Alzheimer Disease · Phase 2
- Amyotrophic Lateral Sclerosis · Phase 2
- Anemia, Aplastic · Phase 1/Phase 2
- Anemia, Sickle Cell · Phase 1/Phase 2
- Angina Pectoris · Phase 2
- Aortic Aneurysm, Abdominal · Phase 2
- Arterial Occlusive Diseases · Phase 2/Phase 3
- Arthritis, Juvenile · Phase 2
- Arthritis, Rheumatoid · Phase 2
- Ascites · Phase 3
- Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome · Phase 1/Phase 2
- Astrocytoma · Phase 1
- Atrophy · Phase 1
- Autism Spectrum Disorder · Phase 1
- Autistic Disorder · Phase 2
- Axis, Cervical Vertebra · Phase 2
- Body Contouring · Phase 2
- Bone Diseases · Phase 1
- Bone Marrow Diseases · Phase 4
- Brain Injuries · Phase 2
- Brain Injuries, Traumatic · Phase 2
- Burns · Phase 2
- Cardiomyopathies · Phase 2/Phase 3
- Cardiovascular Diseases · Phase 2/Phase 3
- Cartilage · Phase 1
- Cartilage Diseases · Phase 3
- Cerebellar Ataxia · Phase 1/Phase 2
- Cerebral Palsy · Phase 2
- Chronic Kidney Disease-Mineral and Bone Disorder · Phase 1/Phase 2
- Chronic Limb-Threatening Ischemia · Phase 3
- Cicatrix · Phase 1
- Colitis, Ulcerative · Phase 1/Phase 2
- Conjunctivitis · Phase 2
- Constriction, Pathologic · Phase 1/Phase 2
- Corneal Diseases · Phase 2
- Coronary Artery Disease · Phase 3
- Coronary Disease · Phase 1
- COVID-19 · Phase 2
- Crohn Disease · Phase 3
- Cystic Fibrosis · Phase 1
- Depressive Disorder, Treatment-Resistant · Phase 1
- Dermatitis, Atopic · Phase 2
- Dermatology · Phase 1/Phase 2
- Diabetes Complications · Phase 1
- Diabetes Mellitus · Phase 1/Phase 2
- Diabetes Mellitus, Type 1 · Phase 1
- Diabetes Mellitus, Type 2 · Phase 2
- Diabetic Foot · Phase 3
- Diabetic Nephropathies · Phase 1
- Drug-Related Side Effects and Adverse Reactions · Phase 1
- Drug Resistant Epilepsy · Phase 1
- Drugs, Investigational · Phase 1
- Dry Eye Syndromes · Phase 2
- Ebstein Anomaly · Phase 1
- Emphysema · Phase 1
- Endothelial Cells · Phase 2
- Epidermal Cells · Phase 1/Phase 2
- Epidermolysis Bullosa · Phase 2
- Erectile Dysfunction · Phase 1/Phase 2
- Facial Hemiatrophy · Phase 1
- Facial Nerve Injuries · Early Phase 1
- Fecal Incontinence · Phase 1/Phase 2
- Filtration · Phase 1/Phase 2
- Foot Ulcer · Phase 1
- Fractures, Bone · Phase 2/Phase 3
- Frailty · Phase 1/Phase 2
- Functional Status · Phase 2
- Gangrene · Phase 2/Phase 3
- Glaucoma, Open-Angle · Phase 1
- Glioblastoma · Phase 1
- Glomerulonephritis, IGA · Phase 1
- Glomerulosclerosis, Focal Segmental · Phase 1
- Goldenhar Syndrome · Phase 1
- Graft vs Host Disease · Phase 2
- Hearing Loss, Sensorineural · Phase 1/Phase 2
- Heart Defects, Congenital · Phase 1
- Heart Diseases · Phase 1
- Heart Failure · Phase 3
- Hematologic Diseases · Phase 1
- Hematologic Neoplasms · Phase 1/Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 1
- Hepatitis C, Chronic · Phase 1
- Hodgkin Disease · Phase 1/Phase 2
- Hormones · Phase 2
- Hypertension, Pulmonary · Phase 1/Phase 2
- Hypertrophy, Left Ventricular · Phase 2
- Hypoplastic Left Heart Syndrome · Phase 1
- Idiopathic Pulmonary Fibrosis · Phase 1/Phase 2
- Immune System Diseases · Phase 3
- Infarction, Middle Cerebral Artery · Phase 2
- Inflammation · Phase 1/Phase 2
- Inflammatory Bowel Diseases · Phase 1
- Intervertebral Disc Degeneration · Phase 1/Phase 2
- Intestinal Diseases · Phase 1
- Intestinal Fistula · Phase 1/Phase 2
- Intestinal Neoplasms · Phase 1
- Intracranial Embolism · Phase 1/Phase 2
- Ischemia · Phase 2/Phase 3
- Ischemic Stroke · Phase 2
- Joint Diseases · Phase 1/Phase 2
- Kidney Diseases · Phase 1/Phase 2
- Kidney Failure, Chronic · Phase 1
- Kidney Transplantation · Phase 1
- Knee Injuries · Phase 3
- Leg Ulcer · Phase 2/Phase 3
- Leukemia, Myeloid, Acute · Phase 2
- Liver · Phase 3
- Liver Cirrhosis · Phase 2
- Liver Cirrhosis, Alcoholic · Phase 2
- Liver Diseases · Phase 2
- Liver Failure · Phase 1
- Liver Regeneration · Phase 1
- Low Back Pain · Phase 1/Phase 2
- Lumbar Vertebrae · Phase 3
- Lung Diseases · Phase 3
- Lung Transplantation · Phase 1/Phase 2
- Lupus Erythematosus, Systemic · Phase 1/Phase 2
- Lymphoma · Phase 1
- Lymphoma, Follicular · Phase 1/Phase 2
- Lymphoma, Large B-Cell, Diffuse · Phase 3
- Lymphoma, Mantle-Cell · Phase 3
- Lymphoma, Non-Hodgkin · Phase 1/Phase 2
- Macular Degeneration · Phase 1/Phase 2
- Mammaplasty · Phase 2
- Mesenchymal Stem Cells · Phase 1/Phase 2
- Mesenchymal Stem Cell Transplantation · Phase 1/Phase 2
- Metabolic Diseases · Phase 2
- Metabolic Syndrome · Phase 1/Phase 2
- Mouth · Phase 1
- Multiple Myeloma · Phase 4
- Multiple Sclerosis · Phase 2
- Multiple Sclerosis, Relapsing-Remitting · Phase 1/Phase 2
- Muscles · Phase 1/Phase 2
- Muscular Dystrophies, Limb-Girdle · Phase 1
- Myelodysplastic Syndromes · Phase 1/Phase 2
- Myocardial Infarction · Phase 2
- Myocardial Ischemia · Phase 3
- Myocardium · Phase 2
- Neoplasms · Phase 1
- Oropharyngeal Neoplasms · Phase 1
- Osteoarthritis · Phase 3
- Osteoarthritis, Hip · Phase 1
- Osteoarthritis, Knee · Phase 3
- Osteonecrosis · Phase 1/Phase 2
- Paralysis · Phase 1
- Parkinson Disease · Phase 2
- Pediatrics · Phase 3
- Periapical Periodontitis · Phase 1/Phase 2
- Peripheral Arterial Disease · Phase 2/Phase 3
- Peripheral Vascular Diseases · Phase 2/Phase 3
- Pneumonia, Bacterial · Phase 1/Phase 2
- Pressure Ulcer · Phase 2
- Primary Ovarian Insufficiency · Phase 1/Phase 2
- Prostatic Hyperplasia · Phase 1/Phase 2
- Prostatic Neoplasms · Phase 1/Phase 2
- Pulmonary Disease, Chronic Obstructive · Phase 1/Phase 2
- Quality of Life · Phase 3
- Rectal Fistula · Phase 3
- Rectovaginal Fistula · Phase 1/Phase 2
- Renal Insufficiency, Chronic · Phase 1
- Respiratory Distress Syndrome · Phase 2
- Respiratory Tract Diseases · Phase 1/Phase 2
- Retinal Degeneration · Phase 1
- Retinitis Pigmentosa · Phase 2
- Rhytidoplasty · Phase 1
- Rotator Cuff Injuries · Phase 2
- Salivary Gland Diseases · Phase 1
- Scleroderma, Systemic · Phase 1/Phase 2
- Severe Acute Respiratory Syndrome · Phase 3
- Shock, Septic · Phase 1
- Sjogren's Syndrome · Phase 1/Phase 2
- Soft Tissue Injuries · Phase 1
- Spinal Cord Injuries · Phase 2
- Spinal Diseases · Phase 1/Phase 2
- Spinal Stenosis · Phase 2
- Spondylolisthesis · Phase 2
- ST Elevation Myocardial Infarction · Phase 2
- Stem Cells · Phase 2
- Stem Cell Transplantation · Phase 1/Phase 2
- Stevens-Johnson Syndrome · Phase 1/Phase 2
- Stress Disorders, Post-Traumatic · Phase 1
- Stroke · Phase 2
- Tennis Elbow · Phase 2
- Thromboangiitis Obliterans · Phase 2
- Thrombocytopenia · Phase 2
- Urinary Bladder Neck Obstruction · Phase 1/Phase 2
- Urinary Incontinence · Phase 2
- Urinary Incontinence, Stress · Phase 3
- Vaginal Diseases · Phase 1/Phase 2
- Varicose Ulcer · Phase 2
- Vascular Access Devices · Phase 1
- Vascular Diseases · Phase 2/Phase 3
- Vasculitis · Phase 1
- Ventricular Dysfunction, Left · Phase 1/Phase 2
- Vocal Cord Paralysis · Phase 3
- Wound Healing · Phase 2
- Wrist · Phase 1
- Xerostomia · Phase 1
Mechanism of action
- Unspecified targetTissue restoration
tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS3ME9TTI5QB ↗
Also known as
- adipose derived mesenchymal stem cell
- adipose derived mesenchymal stem cells
- adipose-derived mesenchymal stem cells
- adipose derived regenerative cells
- adipose-derived regenerative cells
- adipose-derived stem cell
- adipose derived stem cells
- adipose derived stromal cells
- adipose stem cell
- allogeneic adipose derived mesenchymal stem cell
- allogeneic adipose derived stem cells
- allogeneic adipose-derived stem cells
- allogeneic human mesenchymal stem cells
- allogeneic mesenchymal human stem cells
- allogeneic mesenchymal stem cells
- allogeneic mesencymal stem cells
- allogenic adipose-derived stem cells
- allogenic adipose mesenchymal stem cell
- allogenic adipose stem cells
- allogenic mesenchymal stem cell
- allogenic mesenchymal stromal cells
- autologous adipose derived mesenchymal stem cells
- autologous adipose derived mesenchymal stromal cells
- autologous adipose derived regenerative cells
- autologous adipose derived stem cells
- autologous adipose-derived stem cells
- autologous adipose-derived stromal cells
- autologous adipose-derived stromal vascular fraction cells
- autologous adipose stem cell
- autologous adipose tissue derived mesenchymal stem cells
- autologous bone marrow blood
- autologous bone marrow cells
- autologous bone marrow derived cells
- autologous bone marrow-derived cells
- autologous bone marrow derived mesenchymal stem cells
- autologous bone marrow derived mesencymal stem cells
- autologous bone marrow derived stem cell
- autologous bone marrow derived stem cells
- autologous bone-marrow mesenchymal stem cells
- autologous bone marrow stem cell
- autologous bone marrow stem cells
- autologous human bone marrow cells
- donor mesenchymal stem cells
- easc
- elixcyte
- expanded adipose-derived stem cells
- expanded allogeneic adipose-derived stem cells
- expanded allogenic adipose-derived adult stem cells
- expanded autologous adipose-derived adult stem cells
- human mesenchymal stem cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07290946 | Phase 2 | Dec 31, 2025 | University of Copenhagen |
| NCT07106229 | Phase 3 | Nov 30, 2025 | Magellan Stem Cells |
| NCT06840275 | Phase 2 | Sep 1, 2025 | Cell2Cure ApS |
| NCT07010926 | Phase 2 | Aug 15, 2025 | L2 Bio, LLC |
| NCT07048054 | Phase 1/Phase 2 (Phase 2) | Jul 31, 2025 | University of Geneva |
| NCT07048314 | Phase 1/Phase 2 (Phase 2) | Jul 1, 2025 | The University of Texas, Dallas |
| NCT06905834 | Phase 2 | Jun 30, 2025 | Instituto Universitario de Oftalmobiología Aplicada, Spanish Clinical Research Network, University of Salamanca |
| NCT06828666 | Phase 1/Phase 2 (Phase 2) | May 5, 2025 | Amarex Clinical Research, Britecyte |
| NCT06623240 | Phase 2 | Jan 31, 2025 | Hope Biosciences |
| NCT06795620 | Phase 1 | Jan 31, 2025 | University of Toulouse |
| NCT06764004 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2025 | Erciyes University |
| NCT06654193 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2025 | Hope Biosciences, University of Alabama, Birmingham, University of California, San Francisco, University of Texas at Houston |
| NCT06705023 | Phase 2 | Nov 18, 2024 | Government of Kazakhstan, ISAR Klinikum |
| NCT06570291 | Phase 3 | Oct 31, 2024 | WuXi |
| NCT06303752 | Phase 1/Phase 2 (Phase 2) | Oct 9, 2024 | University of Oslo, University of Southern Denmark |
| NCT06488898 | Phase 2 | Jun 13, 2024 | Universidad Autonoma de Madrid |
| NCT05526001 | Phase 3 | Dec 31, 2023 | UnicoCell Biomed CO. LTD |
| NCT05996224 | Phase 3 | Oct 31, 2023 | Cellular Biomedicine Group Ltd. |
| NCT05933434 | Phase 1/Phase 2 (Phase 2) | Oct 31, 2023 | Aarhus University |
| NCT06058572 | Phase 2 | Oct 15, 2023 | Tata Memorial Hospital |
Showing 20 of 336 trials
Page 1 / 17
Organizations
Research & Development (368)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Hope Biosciences | For profit | 25 | 25 | 2 | 2018 |
| Universidad Autonoma de Madrid | Academic/Hospital | 16 | 13 | 2 | 2008 |
| Mayo Clinic | Academic/Hospital | 14 | 13 | 2 | 2013 |
| University of Miami | Academic/Hospital | 13 | 11 | 2 | 2008 |
| Seoul National University | Academic/Hospital | 11 | 5 | 4 | 2007 |
| Anterogen Co., Ltd. | For profit | 10 | 10 | 3 | 2009 |
| University of Texas at Houston | Academic/Hospital | 10 | 7 | 3 | 2009 |
| Royan Institute | Academic/Hospital | 9 | 8 | 3 | 2008 |
| University of Copenhagen | Academic/Hospital | 9 | 8 | 2 | 2014 |
| Kyung Hee University | Academic/Hospital | 6 | 0 | 3 | 2015 |
| Sorrento Therapeutics, Inc. | For profit | 6 | 6 | 1 | 2021 |
| Neurogen Brain and Spine Institute | Academic/Hospital | 5 | 5 | 2 | 2008 |
| University of Barcelona | Academic/Hospital | 5 | 1 | 3 | 2009 |
| University of Sao Paulo | Academic/Hospital | 5 | 4 | 2 | 2005 |
| University of Seville | Academic/Hospital | 5 | 0 | 1 | 2010 |
| University of Tehran | Academic/Hospital | 5 | 0 | 3 | 2008 |
| University of Toulouse | Academic/Hospital | 5 | 3 | 2 | 2009 |
| Vinmec International Hospital | Academic/Hospital | 5 | 5 | 2 | 2014 |
| Andalusian Initiative for Advanced Therapies | Academic/Hospital | 4 | 4 | 1 | 2010 |
| Biostar | For profit | 4 | 4 | 2 | 2007 |
368 organizations
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