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Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Subtype terms (3)
More specific conditions that are subtypes of Stroke in the MeSH hierarchy.
- Brain Infarction
14 drugs (8 approved, 6 experimental)
- Hemorrhagic Stroke
21 drugs (16 approved, 5 experimental)
- Ischemic Stroke
319 drugs (146 approved, 173 experimental)
Drugs by status
Approved for this indication (51)
- neuroaid
- sitagliptin
- azilsartan
- human urinary kallidinogenase
- dipyridamole
- dabigatran
- valsartan
- musk
- nebivolol
- deng zhan sheng mai
- ticlopidine
- edaravone
- simvastatin
- acetylsalicylic acid
- lisinopril
- porcine brain-derived peptide preparation
- mexidol
- edoxaban
- oxygen
- Huatuo Zaizao
- amlodipine
- alteplase
- losartan
- celecoxib
- atenolol
- evolocumab
- stroke herbal medicine
- aliskiren
- dantrolene
- olmesartan
- +21 more
Phase 4 trials (88)
- incobotulinumtoxinA
- insulin human
- melatonin
- argatroban
- propofol
- amphetamine
- quinidine
- methylprednisolone
- yiqitongluo
- pyridoxine
- metoclopramide
- rosuvastatin
- astragalus membranaceus
- fosphenytoin
- enalapril
- tranexamic acid
- onabotulinumtoxinA
- cyanocobalamin
- folic acid
- alprostadil
- cenegermin-bkbj
- baclofen
- enoxaparin
- donepezil
- sodium chloride
- dextromethorphan
- danhong
- acetaminophen
- fludeoxyglucose f-18
- niacin
- +58 more
Phase 3 trials (76)
- levobupivacaine
- Desmoteplase
- telcagepant
- sodium succinate
- multivitamins
- amiodarone
- gabapentin
- norepinephrine
- dapsone
- a2ntx
- clevidipine
- urapidil
- water
- heparin
- whole blood
- acadesine
- urokinase
- Milvexian
- colchicine
- angongniuhuang
- riboflavin
- ceftriaxone
- act017
- shr-1209
- cromoglicic acid
- dm199
- nerinetide
- remifentanil
- lithium
- epoetin
- +46 more
Phase 2 trials (104)
- Alirinetide
- bupropion
- canagliflozin
- allogeneic adipose derived mesenchymal stem cell
- autologous mononuclear stem cell
- coagulation factor viia (recombinant)
- zonampanel monohydrate
- dapagliflozin
- zagociguat
- nicardipine
- tramiprosate
- autologous umbilical cord blood
- piclozotan
- basmisanil
- dp-b99
- rotigotine
- gxnpc1
- human choriogonadotropin alfa
- revacept
- autologous mesenchymal stem cells
- v10153
- exenatide
- crobenetine
- mannitol
- 18f-pbr06
- florbetapir
- infliximab
- ruyizhenbao
- enecadin
- potassium
- +74 more
Phase 1 trials (33)
- bone marrow derived mesenchymal stem cells
- dpoc-4088
- quercetin
- astaxanthin
- umsc01
- hrs-7450
- dimethyltryptamine
- thiamine
- sildenafil
- cyproheptadine
- cnto 0007
- dexamethasone
- aer-271
- oxytocin
- calcium gluconate
- psilocybin
- mtr-601
- calf serum
- ndc-002
- duloxetine
- ferumoxytol
- cobalamin
- interferon beta-1b
- allorx stem cells®
- deferoxamine
- jpi-289
- alirocumab
- allogeneic cord blood
- bt200
- onion
- +3 more
Other trials (57)
- salvianolate
- lycopene
- midodrine
- sevoflurane
- bifidobacterium longum
- carbon dioxide
- vitamin e
- xenon xe-133
- phentolamine mesylate
- tocotrienol
- erythromycin
- potassium chloride
- Collagen Tripeptide
- proline
- high density lipoprotein
- topotecan
- 3k3a-apc
- albumin (Human)
- esmolol
- hua tuo zai zao wan
- ranitidine
- monomethyl fumarate
- hydroxyethyl starch
- prilocaine
- nitroprusside
- shengdi dahuang
- gelidium elegans
- ghrelin
- lysine
- hyaluronic acid
- +27 more
Organizations
Organization Involved with Phase 4 Indications (256)
- Basque Country University
- The NO.4 People's Hospital of Hengshui
- Mackay Medical College
- Shandong University
- National Taiwan University
- National Cerebral and Cardiovascular Center
- Sungkyunkwan University
- Hospital Joan XXIII de Tarragona, Tarragona, Spain
- University of Hamburg
- Kyung Hee University
- Huzhou University
- Nanjing Medical University
- Hospital de Leon
- Hospital de Granollers
- National Rehabilitation Center of Korea
- Northwest University
- National Institute of Mental Health (NIMH)
- Hangzhou City Hospital of TCM
- Zhejiang Chinese Medical University
- Wuzhou city red cross hospital
- King Fahad Medical City
- German Federal Ministry of Education and Research
- Universitat de Vic
- Wenzhou Medical University
- Osakidetza
- Tel Aviv University
- Guangzhou Baiyunshan Qixing Pharmaceutical Co Ltd
- Korea University
- University of Glasgow
- Mianyang Central Hospital
- +226 more
Organization Involved with Phase 3 Indications (200)
- Scienze Neurologiche Ospedaliere
- University of California, Los Angeles
- University of South Florida
- Forest Laboratories
- AstraZeneca
- Clinical Research Centre Hospital Taiping
- Healios K.K.
- University of Michigan
- Umea University
- Hospital Santa Marcelina, Sao Paulo, Brasil
- D-Pharm Ltd.
- Supergene, LLC
- Swiss National Science Foundation
- Health Research Board, Ireland
- National University of Ireland
- Daewoong Pharmaceutical Co. LTD.
- University of Oslo
- Rho, Inc.
- Indonesia's Neurologists Organization (Perdossi)
- Aase and Ejnar Danielsens Foundation
- University of British Columbia
- National Research Council of Thailand
- University of South Carolina
- University of Hiroshima
- Government of Korea
- University of California, San Diego
- University of California, San Francisco
- National Heart, Lung, and Blood Institute (NHLBI)
- Inha University
- Mater Adult Hospital
- +170 more
Organization Involved with Phase 2 Indications (182)
- Jacobs Neurological Institute
- Arca Biopharma, Inc.
- Aldagen
- Baotou Medical University
- Sarasota Memorial Hospital
- Department of Defense
- University of Sherbrooke
- Hospital de Mataró
- Cha Medical University
- Korea Evaluation Institute of Industrial Technology
- Teijin Pharma Limited
- Global Biotech
- Diffusion Pharmaceuticals LLC
- Soonchunhyang University
- Eagle Pharmaceuticals, Inc.
- Monash University
- Thrombolytic Science International
- Kyunghee University Medical Center
- Neuroscience Trials Australia
- Stem Cell Therapeutics Corp.
- Aristotle University of Thessaloniki
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Hebrew University
- Pusan National University
- University of Waterloo
- Memorial University of Newfoundland
- ReNeuron Limited
- Hunan Rui Kang Tong technology development co., LTD
- University of Rochester
- The Central Hospital of Lishui City
- +152 more
Organization Involved with Phase 1 Indications (65)
- Huons Co.,Ltd.
- Yantai YenePharma Co., Ltd.
- The Institute for Rehabilitation and Research (TIRR) Foundation
- Meridigen Biotech Co., Ltd.
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
- Xiyuan Hospital
- AIDS Malignancy Consortium
- Ever Supreme Bio Technology Co., Ltd.
- Government of Finland
- Kessler Foundation
- BHI Therapeutic Sciences
- Inova Health System
- Etablissement Français du Sang
- Novadiscovery
- Masaryk University
- Saint Anne's Hospital
- Prolong Pharmaceuticals
- Servicio de Salud de Castilla La Mancha (SESCAM)
- Instituto de Estudios de Ciencias de la Salud de Castilla y León (IECSCYL)
- Aeromics, Inc.
- Hospital Universitario Hernando Moncaleano Perdomo
- PhytoHealth Corporation
- Neurogen Brain and Spine Institute
- Histocell S.L.
- Spanish National Health System
- Philadelphia College of Osteopathic Medicine
- Andaluz Health Service
- Dow University of Health Sciences
- City University of Hong Kong
- BURL Concepts Inc.
- +35 more
Organization Involved with Other Experimental Indications (42)
- S.Anna Rehabilitation Institute
- Tulane University
- University of Florence
- James N. Kirby Foundation
- Phenox GmbH
- University of Leeds
- Adolphe Rothschild Ophtalmologic Foundation
- University of Saskatchewan
- Stryker
- National Heart Foundation, Australia
- Istituti Clinici Scientifici Maugeri SpA
- Marmara University
- University of Pavia
- University of Gothenburg
- Vitalicious
- University of Southern Denmark
- Université catholique de Louvain
- Washington University in St. Louis
- Medtronic
- University of Western Ontario
- University of Strasbourg
- Universitaetsklinikum Schleswig-Holstein
- Assiut University
- Cairo University
- Loughborough University
- Life Recovery Systems
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- University of Burgundy
- Medical Health Research Infrastructure Council, Australia
- New York Presbyterian Hospital
- +12 more