allogeneic cord blood
Cell therapyexperimental
Cord blood is blood that remains in the placenta and in the attached umbilical cord after childbirth. Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders such as cancer. — Wikipedia
Clinical trial activity
62 trials · 101 clinical orgs · 0 marketing orgs
Phase 1
31
Phase 2
38
Phase 3
4
Phase 4
2
Earliest trial started Jan 1, 1999 (NCT00029380)
Timeline
Indications
Approved for
Studied for
- Anemia, Aplastic · Phase 4
- Anemia, Sickle Cell · Phase 2
- Autism Spectrum Disorder · Phase 1/Phase 2
- Autistic Disorder · Phase 1/Phase 2
- beta-Thalassemia · Phase 2
- Bone Marrow Cells · Phase 1
- Bone Marrow Failure Disorders · Phase 2
- Bone Marrow Transplantation · Phase 1
- Cerebral Palsy · Phase 1/Phase 2
- Child Development · Phase 1/Phase 2
- Corneal Diseases · Phase 1/Phase 2
- COVID-19 · Phase 3
- Drug-Related Side Effects and Adverse Reactions · Phase 2
- Efficiency · Phase 1
- Fetal Blood · Phase 1
- Heart Arrest, Induced · Phase 2
- Hematologic Diseases · Phase 2
- Hematologic Neoplasms · Phase 3
- Hematopoietic Stem Cell Transplantation · Phase 2
- Hemoglobinopathies · Phase 2
- Hodgkin Disease · Phase 3
- Immune System Diseases · Phase 1
- Infusions, Intravenous · Phase 2
- Ischemic Stroke · Phase 2
- Leukemia · Phase 2
- Leukemia, Biphenotypic, Acute · Phase 2
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 2
- Leukemia, Lymphoid · Phase 2
- Leukemia, Monocytic, Acute · Phase 1
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 3
- Leukemia, Myeloid, Acute · Phase 3
- Leukemia, Myeloid, Chronic-Phase · Phase 3
- Leukemia, Myelomonocytic, Acute · Phase 1
- Leukemia, Myelomonocytic, Chronic · Phase 2
- Lymphohistiocytosis, Hemophagocytic · Phase 2
- Lymphoma · Phase 3
- Lymphoma, B-Cell · Phase 2
- Lymphoma, Large-Cell, Immunoblastic · Phase 3
- Lymphoma, Non-Hodgkin · Phase 3
- Lymphoma, Primary Cutaneous Anaplastic Large Cell · Phase 1
- Metabolic Diseases · Phase 2
- Metabolism · Phase 1
- Multiple Myeloma · Phase 2
- Myelodysplastic Syndromes · Phase 3
- Myeloproliferative Disorders · Phase 2
- Neoplasms · Phase 1
- Neuroblastoma · Phase 1
- Osteopetrosis · Phase 2
- Pediatrics · Phase 1
- Post-Acute COVID-19 Syndrome · Phase 3
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Phase 3
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 3
- Primary Myelofibrosis · Phase 2
- Progeria · Phase 1/Phase 2
- Severe Combined Immunodeficiency · Phase 1/Phase 2
- Spinal Cord Injuries · Phase 1/Phase 2
- Stem Cell Transplantation · Phase 1
- Stroke · Early Phase 1
- Transplantation · Phase 1
- Urological Manifestations · Early Phase 1
Mechanism of action
- Unspecified targetTissue restoration
tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCord blood ↗
Also known as
- allogeneic cord blood
- cord blood
- expanded allogeneic cord blood
- ex-vivo expanded cord blood
- ex vivo-expanded cord blood progenitor cells
- haplo-identical cord blood
- haploidentical cord blood
- human cord blood cells
- sibling cord blood
- sibling umbilical cord blood
- unrelated chord blood
- unrelated cord blood
- untreated cord blood
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07184385 | Phase 3 | Mar 31, 2026 | StemCyte, Inc. |
| NCT06680661 | Phase 2 | Nov 15, 2024 | Case Western Reserve University |
| NCT06377982 | Phase 1 | Sep 30, 2024 | StemCyte, Inc., StemCyte International, Ltd. |
| NCT06040476 | Phase 2 | Jan 31, 2024 | StemCyte, Inc. |
| NCT06105658 | Phase 2 | Oct 31, 2023 | Anhui Medical University, University of Science and Technology of China |
| NCT06109064 | Phase 2 | Oct 27, 2023 | Anhui Medical University, University of Science and Technology of China |
| NCT05884333 | Phase 2 | May 22, 2023 | Memorial Sloan-Kettering Cancer Center |
| NCT05682560 | Phase 2 | May 4, 2023 | StemCyte, Inc. |
| NCT05612919 | N/A | Jan 31, 2023 | Banc de Sang i Teixits, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona |
| NCT05515419 | Early Phase 1 (Phase 1) | Jan 3, 2023 | The Medical Pavilion Bahamas |
| NCT05584761 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2022 | Nanjing Medical University |
| NCT04644016 | Phase 2 | Nov 20, 2020 | Memorial Sloan-Kettering Cancer Center |
| NCT04174586 | Phase 1 | Dec 1, 2019 | People's Liberation Army of China |
| NCT03920631 | Phase 1 | Jun 30, 2019 | Duke University |
| NCT03735277 | Phase 1 | Apr 6, 2019 | BHI Therapeutic Sciences |
| NCT03871972 | Phase 1/Phase 2 (Phase 2) | Mar 5, 2019 | Cha Medical University |
| NCT03786744 | Phase 1/Phase 2 (Phase 2) | Oct 12, 2018 | Medical Centre Dinasty |
| NCT03913312 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2018 | Jiao Tong University, Luoyang Central Hospital, Peking University, People's Liberation Army of China, Shandong University, Sun Yat-Sen University, Tai'an Central Hospital, Xiamen University, Xuzhou Medical University, Zhengzhou University |
| NCT03483324 | Phase 1 | Apr 24, 2018 | Angiocrine Bioscience, Memorial Sloan-Kettering Cancer Center |
| NCT03473301 | Phase 1/Phase 2 (Phase 2) | Apr 4, 2018 | Duke University, The Marcus Foundation |
Showing 20 of 62 trials
Page 1 / 4
Organizations
Research & Development (101)
101 organizations
Page 1 / 6