potassium
Potassium is a chemical element; it has symbol K and atomic number 19. It is a silvery white metal that is soft enough to easily cut with a knife. Potassium metal reacts rapidly with atmospheric oxygen to form flaky white potassium peroxide in only seconds of exposure. It was first isolated from potash, the ashes of plants, from which its name derives. In the periodic table, potassium is one of the alkali metals, all of which have a single valence electron in the outer electron shell, which is easily removed to create an ion with a positive charge. In nature, potassium occurs only in ionic salts. Elemental potassium reacts vigorously with water, generating sufficient heat to ignite hydrogen emitted in the reaction, and burning with a lilac-colored flame. It is found dissolved in seawater, and occurs in many minerals such as orthoclase, a common constituent of granites and other igneous rocks. — Wikipedia
Clinical trial activity
29 trials · 38 clinical orgs · 1 marketing orgs
Earliest trial started Sep 1, 1981 (NCT00000501)
Timeline
1980s
- Jan 1, 1981
Earliest Phase 2 Sponsor(trial)
2020s
- Oct 2, 2023
American Regent, Inc. — Marketing Organization
Indications
Approved for
Studied for
- Andersen Syndrome · Phase 1
- Arrhythmias, Cardiac · Phase 3
- Arthritis, Rheumatoid · Phase 1
- Blood Pressure · Phase 3
- Cardiovascular Diseases · Phase 2
- Colonoscopy · Phase 4
- Endoscopy · Phase 4
- Fractures, Bone · Phase 3
- Fractures, Stress · Phase 3
- General Surgery · Phase 4
- Healthy Volunteers · Phase 4
- Heart Diseases · Phase 2
- Heart Failure · Phase 4
- Hyperglycemia · Phase 4
- Hyperkalemia · Phase 2
- Hypertension · Phase 4
- Hypertrophy, Left Ventricular · Phase 4
- Hypokalemia · Phase 2
- Hypotension · Phase 4
- Kidney Diseases · Phase 4
- Obesity · Phase 2
- Pain · Phase 3
- Pharmacology · Phase 4
- Sprains and Strains · Phase 3
- Stroke · Phase 2
- Tendinopathy · Phase 3
- Vascular Diseases · Phase 2
Mechanism of action
- PotassiumSupplementation
potassium - supplementation
Chemistry & pharmacology
SMILES
[K]- Mol. weight
- 39.1 g/mol
- Chirality
- Achiral Molecule
- Inorganic
- Yes
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPotassium ↗
- ChEMBLCHEMBL1201290 ↗
Also known as
- k
- k
- kalium
- kalium
- potassium
- potassium
- potassium
- rdx227675
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07238400 | Phase 2 | Dec 1, 2025 | Harvard University, National Heart, Lung, and Blood Institute (NHLBI) |
| NCT07127705 | N/A | May 21, 2025 | Natural Immune Systems Inc |
| NCT06624956 | Phase 4 | Oct 1, 2024 | University of Washington |
| NCT05593055 | Phase 4 | Apr 30, 2023 | Harvard University |
| NCT06467825 | N/A | Aug 9, 2022 | NASA |
| NCT05411991 | Phase 4 | Jun 12, 2022 | Free University of Brussels, Hasselt University, Roche |
| NCT04642313 | N/A | Oct 26, 2020 | University of Health Sciences Lahore |
| NCT04053816 | Phase 3 | Oct 31, 2019 | Barts & The London NHS Trust, University of London |
| NCT03195647 | Phase 3 | Aug 1, 2017 | University of London |
| NCT03018067 | Phase 2 | Jan 1, 2017 | Ardelyx |
| NCT02822898 | Phase 4 | Jun 1, 2016 | Baxalta, University of Antwerp |
| NCT02697708 | N/A | Feb 1, 2016 | Alliance for Potato Research and Education, Purdue University |
| NCT02481219 | N/A | May 1, 2015 | Medtronic |
| NCT02346786 | Phase 3 | Apr 1, 2015 | Centre de Recherche Rhumatologique et Thermal |
| NCT02236598 | Phase 2 | Jan 1, 2015 | Duke University |
| NCT02135146 | Phase 4 | Jan 31, 2014 | University of Colorado, Denver |
| NCT01825720 | N/A | Mar 1, 2013 | Yonsei University |
| NCT01786629 | Phase 4 | Dec 1, 2012 | Braintree Laboratories |
| NCT01719653 | Phase 4 | Oct 1, 2012 | Gastroenterology Services, Ltd. |
| NCT01575041 | N/A | Jan 1, 2012 | Top Institute Food and Nutrition, Wageningen University |
Organizations
Research & Development (38)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 4 | 2 | 3 | 1981 |
| Harvard University | Academic/Hospital | 3 | 3 | 3 | 2008 |
| National Institute of Neurological Disorders and Stroke (NINDS) | Government | 2 | 0 | 2 | 2006 |
| National Institutes of Health (NIH) | Government | 2 | 0 | 2 | 2008 |
| Roche | For profit | 2 | 0 | 2 | 1999 |
| University of London | Academic/Hospital | 2 | 0 | 1 | 2017 |
| Aarhus University | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Alliance for Potato Research and Education | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Ardelyx | For profit | 1 | 1 | 1 | 2017 |
| Barts & The London NHS Trust | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Baxalta | For profit | 1 | 0 | 1 | 2016 |
| Braintree Laboratories | For profit | 1 | 1 | 1 | 2012 |
| Centre de Recherche Rhumatologique et Thermal | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Duke University | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Free University of Brussels | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Gastroenterology Services, Ltd. | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Hasselt University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Medtronic | For profit | 1 | 1 | 1 | 2015 |
| NASA | Government | 1 | 1 | 1 | 2022 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 1 | 1 | 1999 |
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| American Regent, Inc. | For profit | MKTG | Oct 2, 2023 |