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whole blood

Biologicalmarketed

Approved

Jun 1, 1818

Whole blood (WB) is human blood from a standard blood donation. It is used in the treatment of massive bleeding, in exchange transfusion, and when people donate blood to themselves. One unit of whole blood increases hemoglobin levels by about 10 g/L. Cross matching is typically done before the blood is given. It is given by injection into a vein. — Wikipedia

Clinical trial activity

29 trials · 70 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
13
Phase 3
10
Phase 4
2

Earliest trial started Jul 1, 2003 (NCT00071032)

Timeline

1810s

  1. Jun 1, 1818

    Evidence of US Marketing

2000s

  1. Jan 1, 2003

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • BloodTissue restoration

    tissue restoration - blood

Approval history

  • approvedJun 1, 1818

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • whole blood

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07129031Phase 3Sep 1, 2025Xijing Hospital
NCT06809010N/AMar 12, 2025Etablissement Français du Sang
NCT06495294N/AAug 31, 2024Canadian Blood Services, Hamilton Health Sciences Corporation, Health Sciences North Research Institute, Kingston Health Sciences Centre, Queen's University, Belfast, Unity Health Toronto, University of Toronto, University of Western Ontario
NCT05711485N/AMar 1, 2024Johns Hopkins University, Tropical Diseases Research Centre, Zambia, University of California, San Francisco, University of Maryland
NCT06184828Phase 3Feb 1, 2024Oregon Health and Science University
NCT05744583N/ANov 1, 2022Finnish Red Cross, Päijät Häme Central Hospital, University of Helsinki, University of Tampere
NCT04684719Phase 2Jun 30, 2022Department of Defense, University of Pittsburgh
NCT04988620N/AJun 4, 2021Helse Bergen, University of Bergen
NCT04431999Phase 3Sep 30, 2020Direction Centrale du Service de Santé des Armées, Ecoles militaires de santé de Lyon-Bron, Floralis, TIMC-IMAG
NCT03981484Phase 2Jan 31, 2020University of Arizona
NCT03737669Phase 3Aug 31, 2019Johns Hopkins University, Terumo BCT
NCT03477006Phase 2/Phase 3 (Phase 3)Oct 1, 2018National Heart, Lung, and Blood Institute (NHLBI), University of Pittsburgh
NCT04704869Phase 3Jan 31, 2017Baylor University, NHS Blood and Transplant, University of London, University of Texas at Houston
NCT03434808N/AJan 13, 2017Center for International Blood and Marrow Transplant Research, Fujifilm, National Marrow Donor Program
NCT02861482N/AJan 1, 2015Dongguan Maternity & Child Health Hospital, Guangzhou Medical University, Guangzhou University, Jiangmen Maternity & Child Health Care Hospital, Nanhai Maternity & Child Healthcare Hospital, Shenzhen University, Southern Medical University, Sun Yat-Sen University, The First Maternity & Child Healthcare Hospital of Huizhou, Xiaolan People's Hospital of Zhongshan, Zhongshan Dongsheng hospital
NCT01996683N/ANov 1, 2014Ain Shams University
NCT02118428N/AMar 31, 2014Kwame Nkrumah University of Science and Technology, Terumo BCT
NCT02978833Phase 4Oct 1, 2013Rockefeller University
NCT01789632Phase 2Jan 1, 2013McMaster University, University of Michigan
NCT01946750N/ADec 31, 2012Institut Pasteur, Sanofi-Aventis, University of Paris, University of Versailles
Showing 20 of 29 trials
Page 1 / 2

Organizations

Research & Development (70)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Heart, Lung, and Blood Institute (NHLBI)Government4022003
University of Texas at HoustonAcademic/Hospital3322011
Ain Shams UniversityAcademic/Hospital2222012
Department of DefenseGovernment2022012
Johns Hopkins UniversityAcademic/Hospital2222019
McMaster UniversityAcademic/Hospital2222012
Terumo BCTFor profit2122014
University of MarylandAcademic/Hospital2022003
University of PittsburghAcademic/Hospital2222018
Arthrex, Inc.For profit1012012
Baylor UniversityAcademic/Hospital1012017
Canadian Blood ServicesAcademic/Hospital1012024
Center for International Blood and Marrow Transplant ResearchGovernment1112017
Defence Research and Development CanadaGovernment1012012
Direction Centrale du Service de Santé des ArméesGovernment1112020
Dongguan Maternity & Child Health HospitalAcademic/Hospital1012015
Ecoles militaires de santé de Lyon-BronAcademic/Hospital1012020
Emory UniversityAcademic/Hospital1112009
Etablissement Français du SangAcademic/Hospital1112025
Finnish Red CrossAcademic/Hospital1112022
70 organizations
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