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fludeoxyglucose f-18

Small moleculeapprovedImaging agent

Approved

Aug 19, 1994

Fludeoxyglucose F-18 is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging. — NCATS

Clinical trial activity

372 trials · 248 clinical orgs · 44 marketing orgs

Phase 1
105
Phase 2
132
Phase 3
23
Phase 4
17

Earliest trial started Dec 1, 1996 (NCT00002930)

Timeline

1990s

  1. Aug 19, 1994

    State University of New York, Brooklyn — Earliest FDA Approval

  2. Aug 19, 1994

    State University of New York, Brooklyn — NDA Secondary Org

  3. Aug 19, 1994

    State University of New York, Brooklyn — NDA Organization

  4. Jan 1, 1996

    Cornell University — Earliest Phase 2 Sponsor(trial)

  5. Jan 1, 1997

    Cornell University — Earliest Phase 1 Sponsor(trial)

  6. Jan 1, 1999

    Earliest Phase 3 Sponsor(trial)

2000s

  1. Aug 5, 2004

    Cornell University — NDA Secondary Org

  2. Aug 19, 2005

    Feinstein Institute for Medical Research — NDA Secondary Org

2010s

  1. Feb 25, 2011

    Siemens — Marketing Organization

  2. Feb 14, 2013

    Houston Cyclotron — Marketing Organization

  3. Jun 27, 2013

    University of California, Los Angeles — Marketing Organization

  4. Dec 23, 2013

    University of Wisconsin — Marketing Organization

  5. Jan 13, 2014

    University of Texas at Houston — Marketing Organization

  6. Feb 4, 2014

    Lantheus Medical Imaging — Marketing Organization

  7. Feb 4, 2014

    Pharmalogic Hldgs — Marketing Organization

  8. Feb 5, 2014

    Essential Isotopes, LLC — Marketing Organization

  9. Feb 5, 2014

    Washington University in St. Louis — Marketing Organization

  10. May 9, 2014

    University of California, San Francisco — Marketing Organization

  11. Aug 6, 2014

    University of Iowa — Marketing Organization

  12. Sep 25, 2014

    Harvard University — Marketing Organization

  13. Oct 21, 2014

    Zevacor — Marketing Organization

  14. Oct 21, 2014

    Decatur Memorial Hospital — Marketing Organization

  15. Oct 29, 2014

    CPDC — Marketing Organization

  16. Oct 29, 2014

    University of Pennsylvania — Marketing Organization

  17. Oct 29, 2014

    Isologic Innovative — Marketing Organization

  18. Oct 30, 2014

    Hot Shots Nuclear Medicine — Marketing Organization

  19. Dec 18, 2014

    Shertech Labs Llc — Marketing Organization

  20. Jan 7, 2015

    NCM USA — Marketing Organization

  21. Feb 4, 2015

    Northland Nuclear Medicine — Marketing Organization

  22. Apr 7, 2015

    Precision Nuclear — Marketing Organization

  23. Apr 22, 2015

    Spectron Mrc Llc — Marketing Organization

  24. Apr 22, 2015

    Nukemed — Marketing Organization

  25. Apr 23, 2015

    Methodist Cancer Center, Houston, Texas — Marketing Organization

  26. May 1, 2015

    Biomedical Research Foundation — Marketing Organization

  27. Jun 23, 2015

    Jubilant DraxImage Inc. — Marketing Organization

  28. Jun 23, 2015

    University of Utah — Marketing Organization

  29. Jun 23, 2015

    Jubilant Innovation Ltd. — Marketing Organization

  30. Jul 17, 2015

    University of Michigan — Marketing Organization

  31. Aug 31, 2015

    Queen Hamamatsu Pet Imaging Center — Marketing Organization

  32. Aug 31, 2015

    Sofie — Marketing Organization

  33. Sep 11, 2015

    Stanford University — Marketing Organization

  34. Oct 27, 2015

    Kettering Health Network — Marketing Organization

  35. Oct 30, 2015

    3d Imaging Drug Design & Development — Marketing Organization

  36. Nov 13, 2015

    Cardinal Health — Marketing Organization

  37. Nov 19, 2015

    Midwest Medical Isotopes — Marketing Organization

  38. Apr 11, 2016

    Columbia University — Marketing Organization

  39. Dec 8, 2016

    Memorial Sloan-Kettering Cancer Center — Marketing Organization

2020s

  1. Feb 6, 2020

    The University of Texas, Dallas — Marketing Organization

  2. Dec 16, 2020

    University of Southern California — Marketing Organization

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetOTHER

    Diagnostic agent

  • contrast mediumRadiopaque

    contrast medium radiopaque

Approval history

  • approvedPriority reviewAug 19, 1994

Chemistry & pharmacology

Loading structure…

SMILES

OC[C@H]1O[C@@H](O)[C@H](F)[C@@H](O)[C@@H]1O
Mol. weight
182.15 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Availability
Prescription Only
Imaging
18-fluorine

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 18f
  • 18f-deoxy glucose
  • 18fdg
  • 18fdg
  • (18f)-fdg
  • (18f)-fdg
  • 18-f fdg
  • 18-f fdg
  • 18f fdg
  • 18f fdg
  • 18f fdg
  • 18f fdg
  • 18f-fdg
  • 18f-fdg
  • 18f-fdg
  • 18f fludeoxyglucose
  • 18f fluoro-2-deoxy-2-d-glucose
  • 18f fluoro-2-deoxy-2-d-glucose
  • 18f-fluoro-2-deoxy-d-glucose
  • 18f-fluoro-2-deoxy-d-lucose
  • 18f fluoro-deoxi-glucose
  • 18f fluorodeoxyglucose
  • 18f fluorodeoxyglucose
  • 18f-fluorodeoxyglucose
  • 18f-fluorodeoxyglucose
  • 18f fluoroglucose
  • 18f-flurodeoxyglucose
  • 2-deoxy-2 [f-18] fluoro-2-d-glucose
  • 2-deoxy-2 [f-18] fluoro-2-d-glucose
  • 2-fluoro-2-deoxyglucose
  • 2-fluoro-2-deoxyglucose
  • f-18 fluorodeoxyglucose
  • fdg
  • fdg
  • fludeoxyglucose
  • fludeoxyglucose
  • fludeoxyglucose
  • fludeoxyglucose (18f)
  • fludeoxyglucose (18f)
  • fludeoxyglucose (18f)
  • fludeoxyglucose (18f)
  • fludeoxyglucose (18f)
  • fludeoxyglucose f 18
  • fludeoxyglucose f 18
  • fludeoxyglucose f 18
  • fludeoxyglucose f-18
  • fludeoxyglucose f-18
  • fludeoxyglucose f-18
  • fludeoxyglucose f-18
  • fludeoxyglucose f-18
  • fludeoxyglucose f-18
  • fludeoxyglucose-f18
  • fludeoxyglucose-f18
  • fludeoxyglucose, f-18
  • fludeoxyglucose, f-18
  • fluordeoxyglucose
  • fluorine-18 fludeoxyglucose
  • fluorine f 18 fluorodeoxyglucose
  • fluorine f 18 fluorodeoxyglucose
  • fluorodeoxyglucose
  • fluorodeoxyglucose
  • fluorodeoxyglucose f 18
  • fluorodeoxyglucose f 18
  • fluoro-d-glucose
  • fluoro-d-glucose

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07278856Phase 1Apr 27, 2026City of Hope National Medical Center, National Cancer Institute (NCI)
NCT07293247Phase 2Mar 14, 2026National Cancer Institute (NCI)
NCT06815029Phase 1Jan 2, 2026City of Hope National Medical Center, National Cancer Institute (NCI)
NCT07097363Phase 2Jan 1, 2026AbbVie, University of Washington
NCT07066709Phase 2Dec 31, 2025University of Wisconsin
NCT07285993Phase 2Dec 30, 2025Icahn School of Medicine at Mount Sinai
NCT07118176Phase 1Aug 1, 2025University of California, Los Angeles
NCT07087106Phase 4Jul 31, 2025Genzyme, Harvard University
NCT07089641Phase 1Jul 28, 2025University of California, Los Angeles
NCT07023861Early Phase 1 (Phase 1)Jul 1, 2025Jiangnan University
NCT07023848Early Phase 1 (Phase 1)Jul 1, 2025Jiangnan University
NCT07301801Early Phase 1 (Phase 1)Jun 12, 2025Huazhong University of Science and Technology
NCT06956391Phase 2May 12, 2025—
NCT06820957Phase 2/Phase 3 (Phase 3)Apr 15, 2025National Cancer Institute (NCI)
NCT06995976Early Phase 1 (Phase 1)Mar 1, 2025Fujian Medical University
NCT06715020N/ADec 31, 2024Cancer Hospital of Yunnan provinceal, Peking University
NCT06717113Early Phase 1 (Phase 1)Dec 15, 2024Peking University
NCT06502691Phase 1/Phase 2 (Phase 2)Dec 1, 2024Breast Cancer Research Foundation, University of Washington
NCT06630845N/ANov 30, 2024General Electric, Society of Abdominal Radiology, University of California, San Francisco
NCT06503146Phase 2Nov 17, 2024National Cancer Institute (NCI)
Showing 20 of 372 trials
Page 1 / 19

Organizations

Research & Development (248)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government993841996
University of PennsylvaniaAcademic/Hospital171541999
Cornell UniversityAcademic/Hospital161141996
Stanford UniversityAcademic/Hospital161542006
University of WashingtonAcademic/Hospital161322005
Mayo ClinicAcademic/Hospital131142008
National Institutes of Health (NIH)Government12441998
Peking UniversityAcademic/Hospital111032022
Washington University in St. LouisAcademic/Hospital11741999
University of California, Los AngelesAcademic/Hospital9832007
University of Texas at HoustonAcademic/Hospital9732004
University of TorontoAcademic/Hospital9732008
Harvard UniversityAcademic/Hospital8542003
Chinese Academy of Medical SciencesAcademic/Hospital7732013
Case Western Reserve UniversityAcademic/Hospital6532004
City of Hope National Medical CenterAcademic/Hospital6522007
Johns Hopkins UniversityAcademic/Hospital6332004
Ohio State UniversityAcademic/Hospital6532004
University of OttawaAcademic/Hospital6532010
Radboud UniversityAcademic/Hospital5322006
248 organizations
Page 1 / 13

Marketing (49)

OrganizationOrg typeRelationshipDate
3d Imaging Drug Design & DevelopmentFor profitMKTGOct 30, 2015
Biomedical Research FoundationAcademic/HospitalMKTGMay 1, 2015
CPDCFor profitMKTGOct 29, 2014
Cardinal HealthAcademic/HospitalMKTGNov 13, 2015
Columbia UniversityAcademic/HospitalMKTGApr 11, 2016
Cornell UniversityAcademic/HospitalNDA2Aug 5, 2004
Decatur Memorial HospitalAcademic/HospitalMKTGOct 21, 2014
Essential Isotopes, LLCFor profitMKTGFeb 5, 2014
Feinstein Institute for Medical ResearchAcademic/HospitalNDA2Aug 19, 2005
Harvard UniversityAcademic/HospitalSYNOct 30, 2014
Harvard UniversityAcademic/HospitalMKTGSep 25, 2014
Hot Shots Nuclear MedicineFor profitMKTGOct 30, 2014
Houston CyclotronFor profitMKTGFeb 14, 2013
Isologic InnovativeFor profitMKTGOct 29, 2014
Jubilant DraxImage Inc.For profitMKTGJun 23, 2015
Jubilant Innovation Ltd.For profitMKTGJun 23, 2015
Kettering Health NetworkAcademic/HospitalMKTGOct 27, 2015
Lantheus Medical ImagingFor profitMKTGFeb 4, 2014
Memorial Sloan-Kettering Cancer CenterAcademic/HospitalMKTGDec 8, 2016
Methodist Cancer Center, Houston, TexasAcademic/HospitalMKTGApr 23, 2015
Midwest Medical IsotopesFor profitMKTGNov 19, 2015
NCM USAFor profitMKTGJan 7, 2015
Northland Nuclear MedicineFor profitMKTGFeb 4, 2015
NukemedFor profitMKTGApr 22, 2015
Pharmalogic HldgsFor profitMKTGFeb 4, 2014
Precision NuclearFor profitMKTGApr 7, 2015
Queen Hamamatsu Pet Imaging CenterAcademic/HospitalMKTGAug 31, 2015
Shertech Labs LlcFor profitMKTGDec 18, 2014
SiemensFor profitMKTGFeb 25, 2011
SofieFor profitMKTGAug 31, 2015
Spectron Mrc LlcFor profitMKTGApr 22, 2015
Stanford UniversityAcademic/HospitalMKTGSep 11, 2015
State University of New York, BrooklynAcademic/HospitalNDA2Aug 19, 1994
State University of New York, BrooklynAcademic/HospitalNDAAug 19, 1994
The University of Texas, DallasAcademic/HospitalMKTGFeb 6, 2020
University of California, Los AngelesAcademic/HospitalMKTGJun 27, 2013
University of California, San FranciscoAcademic/HospitalMKTGMay 9, 2014
University of IowaAcademic/HospitalMKTGAug 6, 2014
University of MichiganAcademic/HospitalSYNOct 29, 2014
University of MichiganAcademic/HospitalMKTGJul 17, 2015
University of PennsylvaniaAcademic/HospitalMKTGOct 29, 2014
University of PennsylvaniaAcademic/HospitalSYNAug 5, 2013
University of Southern CaliforniaAcademic/HospitalMKTGDec 16, 2020
University of Texas at HoustonAcademic/HospitalMKTGJan 13, 2014
University of UtahAcademic/HospitalMKTGJun 23, 2015
University of WisconsinAcademic/HospitalMKTGDec 23, 2013
University of WisconsinAcademic/HospitalMKTGDec 23, 2013
Washington University in St. LouisAcademic/HospitalMKTGFeb 5, 2014
ZevacorFor profitMKTGOct 21, 2014