salvianolate
Small moleculeexperimental
Salvia miltiorrhiza, also known as red sage, redroot sage, Chinese sage, or danshen, is a perennial plant in the genus Salvia, highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at 90 to 1,200 m elevation, preferring grassy places in forests, hillsides, and along stream banks. The specific epithet miltiorrhiza means "red ochre root". — Wikipedia
Clinical trial activity
11 trials · 18 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
1
Phase 3
0
Phase 4
5
Earliest trial started Jan 1, 2013 (NCT01825759)
Timeline
Indications
Approved for
Studied for
- Angina Pectoris · Phase 4
- Angina, Stable · Phase 4
- Angina, Unstable · Phase 4
- Coronary Disease · Phase 4
- Diabetes Mellitus · Phase 1
- Essential Hypertension · Phase 4
- Healthy Volunteers · Phase 1
- Inflammation · Phase 4
- Intermittent Claudication · Phase 2
- Myocardial Infarction · Phase 4
- Peripheral Arterial Disease · Phase 2
Mechanism of action
- Unspecified targetAntioxidant
antioxidant
Chemistry & pharmacology
Loading structure…
SMILES
O=C(/C=C/c1ccc(O)c(O)c1/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O- Mol. weight
- 494.45 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSalvia miltiorrhiza ↗
- ChEMBLCHEMBL457077 ↗
Also known as
- danshen gegen capsule
- salvianolate
- salvianolate
- salvianolic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04931628 | N/A | Sep 1, 2021 | Ningbo No. 1 Hospital, Red Cross Hospital, Hangzhou, China, Wenzhou Medical University, Xiaoshan People's Hospital, Zhejiang Chinese Medical University, Zhejiang University |
| NCT03908242 | Phase 1 | Apr 8, 2019 | Peking University |
| NCT03791463 | Phase 1 | Dec 20, 2018 | Peking University |
| NCT03791125 | Phase 1 | Nov 20, 2018 | Chinese Academy of Medical Sciences, Peking University, Shandong Huizhi Pharmaceutical Technology Co., Ltd. |
| NCT03306550 | N/A | Oct 10, 2017 | China Academy of Chinese Medical Sciences |
| NCT03045562 | Phase 4 | Jan 20, 2017 | Fudan University, Green Valley Group of China |
| NCT02870764 | Phase 4 | Sep 1, 2016 | Huazhong University of Science and Technology, Taiyuan Fourth People's Hospital |
| NCT03037047 | Phase 4 | May 11, 2016 | Green Valley Group of China, People's Liberation Army of China |
| NCT02694848 | Phase 4 | Feb 1, 2016 | China Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Traditional Chinese Medicine, People's Liberation Army of China |
| NCT02380794 | Phase 2 | Sep 1, 2015 | Chinese University of Hong Kong |
| NCT01825759 | Phase 4 | Jan 1, 2013 | Sichuan University |
Showing 11 of 11 trials
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Organizations
Research & Development (18)
18 organizations
Page 1 / 1