autologous umbilical cord blood
Cell therapyexperimental
Cord blood is blood that remains in the placenta and in the attached umbilical cord after childbirth. Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders such as cancer. — Wikipedia
Clinical trial activity
123 trials · 117 clinical orgs · 0 marketing orgs
Phase 1
50
Phase 2
67
Phase 3
5
Phase 4
0
Earliest trial started Feb 1, 1993 (NCT00212407)
Timeline
Indications
Studied for
- Acute Febrile Encephalopathy · Phase 2
- Allografts · Phase 3
- Alzheimer Disease · Early Phase 1
- Anemia, Aplastic · Phase 2
- Anemia, Diamond-Blackfan · Phase 2
- Anemia, Neonatal · Phase 1
- Anemia, Refractory · Phase 2
- Anemia, Sickle Cell · Phase 1
- Autism Spectrum Disorder · Phase 2
- Autistic Disorder · Phase 2
- Bone Marrow Cells · Phase 2
- Bone Marrow Failure Disorders · Phase 2
- Brain Injuries · Phase 2
- Brain Injuries, Traumatic · Phase 1/Phase 2
- Brain Ischemia · Phase 1
- Breast Neoplasms · Phase 1/Phase 2
- Bronchopulmonary Dysplasia · Phase 2
- Burkitt Lymphoma · Phase 3
- Cardiac Output, Low · Phase 1/Phase 2
- Cerebral Infarction · Phase 1/Phase 2
- Cerebral Intraventricular Hemorrhage · Phase 1
- Cerebral Palsy · Phase 2
- Child Development Disorders, Pervasive · Phase 2
- Cicatrix · Phase 2
- Diabetes Mellitus, Type 1 · Phase 1/Phase 2
- Enterocolitis, Necrotizing · Early Phase 1
- Fanconi Anemia · Phase 2
- Genetic Diseases, Inborn · Early Phase 1
- Graft vs Host Disease · Phase 2
- Growth and Development · Early Phase 1
- Hearing Loss · Phase 1
- Heart Defects, Congenital · Phase 1/Phase 2
- Hematologic Neoplasms · Phase 2
- Hematology · Phase 2
- Hemoglobinopathies · Phase 1
- Hernias, Diaphragmatic, Congenital · Phase 1
- Hodgkin Disease · Phase 3
- Hypoplastic Left Heart Syndrome · Phase 2
- Hypoxia-Ischemia, Brain · Phase 1/Phase 2
- Infant, Premature · Phase 1
- Infant, Premature, Diseases · Phase 1
- Intraocular Lymphoma · Phase 2
- Ischemic Stroke · Phase 1/Phase 2
- Kidney Neoplasms · Phase 1/Phase 2
- Leukemia · Phase 2
- Leukemia, Biphenotypic, Acute · Phase 2
- Leukemia, Hairy Cell · Phase 2
- Leukemia, Large Granular Lymphocytic · Phase 2
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 2
- Leukemia, Lymphoid · Phase 1
- Leukemia-Lymphoma, Adult T-Cell · Phase 2
- Leukemia, Monocytic, Acute · Phase 2
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 3
- Leukemia, Myeloid, Acute · Phase 3
- Leukemia, Myeloid, Chronic-Phase · Phase 2
- Leukemia, Myelomonocytic, Acute · Phase 1
- Leukemia, Myelomonocytic, Chronic · Phase 2
- Leukemia, Myelomonocytic, Juvenile · Phase 2
- Leukemia, Plasma Cell · Phase 2
- Leukemia, Prolymphocytic · Phase 2
- Lymphoma · Phase 2
- Lymphoma, B-Cell, Marginal Zone · Phase 2
- Lymphoma, Follicular · Phase 3
- Lymphoma, Large B-Cell, Diffuse · Phase 2
- Lymphoma, Large-Cell, Anaplastic · Phase 2
- Lymphoma, Large-Cell, Immunoblastic · Phase 3
- Lymphoma, Mantle-Cell · Phase 3
- Lymphoma, Non-Hodgkin · Phase 3
- Lymphoma, Primary Cutaneous Anaplastic Large Cell · Phase 2
- Lymphoma, T-Cell · Phase 2
- Lymphoma, T-Cell, Peripheral · Phase 2
- Lymphomatoid Granulomatosis · Phase 2
- Lysosomal Storage Diseases · Phase 1
- Metabolic Diseases · Phase 1/Phase 2
- Metabolism, Inborn Errors · Phase 1
- Multiple Myeloma · Phase 2
- Myelodysplastic-Myeloproliferative Diseases · Phase 2
- Myelodysplastic Syndromes · Phase 3
- Myeloproliferative Disorders · Phase 2
- Myocardial Infarction · Phase 1
- Neonatology · Phase 1/Phase 2
- Neoplasm Metastasis · Phase 1
- Neoplasms · Phase 2
- Neoplasms, Plasma Cell · Phase 1
- Neuroblastoma · Phase 2
- Neutropenia · Phase 2
- Osteopetrosis · Phase 2/Phase 3
- Perinatal Death · Phase 2
- Pharmacokinetics · Phase 2
- Pharmacological and Toxicological Phenomena · Phase 1
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Phase 3
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 3
- Primary Immunodeficiency Diseases · Phase 1
- Primary Myelofibrosis · Phase 2
- Respiratory Distress Syndrome · Phase 1
- Sarcoma · Phase 1
- Sezary Syndrome · Phase 2
- Spinal Cord Injuries · Phase 1/Phase 2
- Stroke · Phase 2
- Testicular Neoplasms · Phase 2
- Thalassemia · Phase 1
- Thrombocytopenia · Phase 1/Phase 2
- Thymoma · Phase 2
- Transplantation · Phase 2
- Ventilation · Phase 1
- Waldenstrom Macroglobulinemia · Phase 2
Mechanism of action
- Stem CellTissue restoration
Stem Cell tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCord blood ↗
Also known as
- autologous cord blood
- autologous cord blood cells
- autologous human cord blood derived stem cells
- autologous human umbilical cord blood
- autologous umbilical cord blood
- autologous umbilical cord blood stem cells
- ex vivo cd3/cd28 costimulated umbilical cord blood t cells
- umbilical cord blood
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07201233 | N/A | Nov 1, 2025 | Qilu Pharmaceutical Co., Ltd., Tianjin Medical University |
| NCT07208344 | Early Phase 1 (Phase 1) | Jul 31, 2025 | Anhui Medical University |
| NCT05669079 | Phase 3 | Feb 1, 2023 | Soochow University |
| NCT04420494 | N/A | Apr 20, 2022 | Chinese Academy of Medical Sciences |
| NCT05138276 | Early Phase 1 (Phase 1) | Sep 1, 2021 | Guangdong Women and Children Hospital |
| NCT04687657 | Phase 1 | Jan 1, 2021 | Jiao Tong University |
| NCT04243382 | Phase 2 | Jan 31, 2020 | Tel Aviv University |
| NCT04243408 | Phase 2 | Jan 31, 2020 | Tel Aviv University |
| NCT04034615 | Phase 2 | Oct 20, 2019 | Maternal and Child Health Hospital of Foshan |
| NCT04768816 | Phase 1 | Jul 1, 2019 | Guangdong Women and Children Hospital |
| NCT03779711 | Phase 2 | Apr 30, 2019 | Children's Hospital Los Angeles, Mayo Clinic, University of Colorado, University of Minnesota, University of Oklahoma, University of Pennsylvania |
| NCT03774537 | Phase 1/Phase 2 (Phase 2) | Mar 1, 2019 | Chongqing Medical University |
| NCT03760900 | Phase 2 | Mar 1, 2019 | Guangdong Women and Children Hospital |
| NCT03855202 | Phase 1 | Feb 24, 2019 | Guangdong Women and Children Hospital |
| NCT04007224 | Phase 1 | Jan 17, 2019 | Fundatia Bio-Forum, Spitalul Angiomedica |
| NCT03696745 | Phase 1 | Nov 1, 2018 | Guangdong Women and Children Hospital |
| NCT03526588 | Phase 1 | Aug 1, 2018 | Texas Medical Center Regenerative Medicine Consortium, University of Texas at Houston |
| NCT03873506 | Phase 1 | Jul 1, 2018 | Chongqing Medical University |
| NCT04311476 | Phase 2 | Jul 1, 2018 | Guangdong Women and Children Hospital |
| NCT03558269 | Phase 1/Phase 2 (Phase 2) | Jun 15, 2018 | Tel Aviv University |
Showing 20 of 123 trials
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Organizations
Research & Development (117)
117 organizations
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