Vascular Diseases
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Subtype terms (46)
More specific conditions that are subtypes of Vascular Diseases in the MeSH hierarchy.
- Aneurysm
39 drugs (35 approved, 4 experimental)
- Aneurysm, False
- Angiodysplasia
4 drugs approved
- Angioedema
30 drugs (22 approved, 8 experimental)
- Angiomatosis
3 drugs approved
- Aortic Diseases
35 drugs (29 approved, 6 experimental)
- Arterial Occlusive Diseases
111 drugs (79 approved, 32 experimental)
- Arteriovenous Malformations
15 drugs (13 approved, 2 experimental)
- Capillary Leak Syndrome
2 drugs approved
- Cerebrovascular Disorders
83 drugs (58 approved, 25 experimental)
- Colitis, Ischemic
1 drug experimental
- Compartment Syndromes
- Diabetic Angiopathies
9 drugs (6 approved, 3 experimental)
- Embolism and Thrombosis
11 drugs (10 approved, 1 experimental)
- Hand-Arm Vibration Syndrome
- Hemorrhoids
65 drugs (38 approved, 27 experimental)
- Hemostatic Disorders
7 drugs (2 approved, 5 experimental)
- Hepatic Veno-Occlusive Disease
3 drugs approved
- Hyperemia
13 drugs (9 approved, 4 experimental)
- Hypertension
637 drugs (322 approved, 315 experimental)
- Hypotension
141 drugs (105 approved, 36 experimental)
- Mesenteric Ischemia
6 drugs (5 approved, 1 experimental)
- Myocardial Ischemia
203 drugs (135 approved, 68 experimental)
- Optic Neuropathy, Ischemic
24 drugs (19 approved, 5 experimental)
- Peliosis Hepatis
- Penetrating Atherosclerotic Ulcer
- Peripheral Vascular Diseases
79 drugs (42 approved, 37 experimental)
- Prehypertension
48 drugs (31 approved, 17 experimental)
- Pulmonary Veno-Occlusive Disease
3 drugs approved
- Reperfusion Injury
88 drugs (71 approved, 17 experimental)
- Retinal Vein Occlusion
46 drugs (30 approved, 16 experimental)
- Scimitar Syndrome
- Spinal Cord Vascular Diseases
- Splenic Infarction
- Stenosis, Pulmonary Vein
2 drugs approved
- Superior Vena Cava Syndrome
- Telangiectasis
8 drugs (6 approved, 2 experimental)
- Thoracic Outlet Syndrome
4 drugs approved
- Varicocele
5 drugs (4 approved, 1 experimental)
- Varicose Veins
28 drugs (18 approved, 10 experimental)
- Vascular Fistula
- Vascular Neoplasms
1 drug approved
- Vascular System Injuries
10 drugs (5 approved, 5 experimental)
- Vasculitis
50 drugs (32 approved, 18 experimental)
- Vasoplegia
13 drugs (12 approved, 1 experimental)
- Venous Insufficiency
26 drugs (7 approved, 19 experimental)
Drugs by status
Approved for this indication (2)
Phase 4 trials (44)
- propofol
- heparin
- urea
- dabigatran
- cangrelor
- esmolol
- butylphthalide
- empagliflozin
- gabapentin
- sevoflurane
- paclitaxel
- liraglutide
- dolutegravir
- calcium
- ketorolac
- nitroaspirin
- evolocumab
- atorvastatin
- ticagrelor
- acetaminophen
- prasugrel
- lidocaine
- rocuronium
- sitagliptin
- celecoxib
- sevelamer
- sirolimus
- acetylsalicylic acid
- fluorescein
- bevacizumab
- +14 more
Phase 3 trials (35)
- simvastatin
- vitamin e
- beetroot juice
- beta carotene
- ambrisentan
- chlorthalidone
- atenolol
- doxycycline
- nifedipine
- gadobutrol
- tenecteplase
- warfarin
- bovine colostrum
- icosapent ethyl
- magnesium oxide
- gadopenteate dimeglumine
- niacin
- vitamin c
- telcagepant
- pravastatin
- rauwolfia alkaloids
- shenfu
- tocilizumab
- pentoxifylline
- vancomycin
- vildagliptin
- allogeneic adipose derived mesenchymal stem cell
- gentamicin
- ayurvedic suved
- bivalirudin
- +5 more
Phase 2 trials (49)
- ranibizumab
- sodium nitrite
- nitroglycerin
- phentermine
- calcium carbonate
- bms-582949
- edaravone
- progesterone
- enalapril
- trametinib
- tenofovir
- amlodipine
- ritonavir
- potassium
- albumin (Human)
- hydralazine
- ifetroban
- acetylcholine chloride
- labetalol
- fluoxetine
- pegylated carboxyhemoglobin
- nicardipine
- mirdametinib
- alpelisib
- pittsburgh compound b
- alendronic acid
- pz-128
- dipyridamole
- darunavir
- estradiol
- +19 more
Phase 1 trials (15)
Other trials (60)
- ezetimibe
- metronidazole
- brimonidine
- cinacalcet
- norepinephrine
- cocoa bean
- doxorubicin
- latanoprost
- rosuvastatin
- indocyanine green
- menaquinone
- tobacco
- olmesartan
- pamidronate
- cow milk
- phytosterol
- anacetrapib
- nicotine
- rotigaptide
- cyclophosphamide
- gelofusin
- anastrozole
- testosterone
- fluconazole
- spironolactone
- urocortin 3
- ciprofloxacin
- strawberry
- atropine
- beef
- +30 more
Organizations
Organization Involved with Phase 4 Indications (78)
- Abbott
- Regeneron
- Daiichi Sankyo
- Bristol-Myers Squibb
- Amgen
- AstraZeneca
- Merck
- Eli Lilly
- Pfizer
- Novartis
- Baxalta
- Bayer
- Chengdu Kanghong Biotech Co.,Ltd.
- Accumetrics, Inc.
- Otsuka
- Danish Heart Foundation
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Central South University
- Augusta University
- Barnsley Hospital
- Harvard University
- Duke University
- University of Washington
- Harbin Medical University
- Hoosier Cancer Research Network
- Hawaii Pacific Health
- Masaryk University
- Los Angeles Biomedical Research Institute
- +48 more
Organization Involved with Phase 3 Indications (81)
- Servier
- United Therapeutics
- Bracco
- Genzyme
- Sanofi
- Alexion
- Anesiva, Inc.
- Arena Pharmaceuticals
- Beijing Northland Biotech. Co., Ltd.
- GlaxoSmithKline
- Kos Pharmaceuticals
- Leadiant Biosciences, Inc.
- Omrix Biopharmaceuticals, Inc.
- Ethicon
- Neovii Biotech
- ZonMw: The Netherlands Organisation for Health Research and Development
- National Institutes of Health (NIH)
- National Cancer Institute (NCI)
- National Center for Complementary and Integrative Health (NCCIH)
- Anand, Sonia, M.D.
- Aarhus University
- University of Pittsburgh
- Brown University
- Case Western Reserve University
- Cedars-Sinai Medical Center
- University of London
- Dartmouth University
- Hospital do Coracao
- Katholieke Universiteit Leuven
- Lund University
- +51 more
Organization Involved with Phase 2 Indications (74)
- Actelion
- Medistem
- Celgene
- Genentech
- Arca Biopharma, Inc.
- Archemix Corp.
- BioGenCell Ltd.
- Biopure Corporation
- Diagram B.V.
- Factor Therapeutics Ltd.
- Endovasc
- Kobe University
- Mateon Therapeutics
- MultiGene Vascular Systems Ltd.
- Nissan Chemical Industries
- Omeros Corporation
- Iveric Bio
- Parexel
- Sangart
- Valentis
- TCA Cellular Therapy
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institute on Aging (NIA)
- University of Roma La Sapienza
- Emory University
- Health Decisions
- Indiana University
- Johns Hopkins University
- Memorial University of Newfoundland
- Monash University
- +44 more
Organization Involved with Phase 1 Indications (16)
- Mallinckrodt
- Lpath, Inc.
- Pluristem Ltd.
- Polysan, Ltd.
- Mid-Atlantic Retina Consultations, Inc.
- LifeBridge Health
- Thomas Jefferson University
- South China Research Center for Stem Cell and Regenerative Medicine
- University of Naples Frederico II
- Vanderbilt University
- Southern Medical University
- University of Wisconsin
- The Retina Center at Pali Momi
- Humboldt University
- Foxhollow Technologies
- People's Liberation Army of China
Organization Involved with Other Experimental Indications (28)
- Unilever
- Shahid Beheshti University of Medical Sciences
- Boston University
- Florida State University
- Manhattan Eye, Ear & Throat Hospital
- Medical University of Lodz
- NHS Lothian
- Northwell Health
- Sanford Health
- St. John's Research Institute
- University of Edinburgh
- University of Florida
- University of Limerick
- University of Palermo
- University of Cambridge
- University of Ulsan
- Adolphe Rothschild Ophtalmologic Foundation
- University of Missouri
- National University of Singapore
- National Taiwan University
- Aspect Clinical
- The University of Hong Kong
- Catholic University of Korea
- Commonwealth Scientific and Industrial Research Organisation, Australia
- Nanyang Technological University
- California Strawberry Commission
- Government of Scotland
- Cambridge Theranostics Ltd