phytosterol
Botanicalexperimental
A sterol is any organic compound with a skeleton closely related to cholestan-3-ol. The simplest sterol is gonan-3-ol, which has a formula of C17H28O, and is derived from that of gonane by replacement of a hydrogen atom on C3 position by a hydroxyl group. It is therefore an alcohol of gonane. — Wikipedia
Clinical trial activity
46 trials · 59 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
6
Phase 3
4
Phase 4
6
Earliest trial started Jun 1, 2003 (NCT00802516)
Timeline
Indications
Approved for
Studied for
- Cardiovascular Diseases · Phase 3
- Coronary Artery Disease · Phase 2/Phase 3
- Dietary Supplements · Phase 4
- Drug-Related Side Effects and Adverse Reactions · Phase 2
- Dyslipidemias · Phase 4
- Heart Disease Risk Factors · Phase 4
- Hypercholesterolemia · Phase 4
- Hyperlipidemias · Phase 4
- Metabolic Syndrome · Phase 3
- Osteoporosis · Phase 1
- Postmenopause · Phase 1
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSterol ↗
- WikipediaStanol ester ↗
- WikipediaPhytosterol ↗
Also known as
- benecol
- disodium ascorbyl campestanyl phosphate
- disodium ascorbyl phytostanol phosphate
- disodium ascorbyl phytostanol phosphate
- disodium ascorbyl sitostanyl phosphate
- fm-vp4 compound
- fm-vp4 cpd
- phytostanol phosphoryl ascorbate
- phytosterol
- phytosterol
- phytosterol ester
- phytosterol esters
- plant stanol ester
- plant stanol ester
- plant stanol esters
- plant sterol
- plant sterol
- plant sterols
- plant sterols
- stanol ester
- sterol
- sterol
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06331195 | N/A | Aug 31, 2024 | Hospital do Coracao, Instituto Dante Pazzanese de Cardiologia, National Institute of Cardiology, Laranjeiras, Brazil, University of Sao Paulo |
| NCT06697977 | N/A | Aug 15, 2023 | University of Jordan |
| NCT05695937 | N/A | May 22, 2023 | Federal University of Health Science of Porto Alegre, Federal University of Sao Paulo, Hospital do Coracao, National Institute of Cardiology, Laranjeiras, Brazil, University of Sao Paulo |
| NCT05265455 | N/A | Oct 1, 2021 | University of Bologna |
| NCT05126056 | N/A | Sep 1, 2021 | Raisio Group, University of Helsinki |
| NCT04030247 | Phase 4 | Sep 1, 2019 | Piper Biosciences, Stanford University |
| NCT03550287 | Phase 4 | May 8, 2017 | Institute for Health Research IdiPAZ, Universidad Autonoma de Madrid |
| NCT02969720 | Phase 3 | Mar 1, 2017 | Universidad de los Andes |
| NCT02881658 | N/A | May 1, 2016 | The University of Hong Kong |
| NCT02728583 | N/A | Apr 1, 2016 | Unilever |
| NCT03284918 | N/A | Jan 31, 2016 | Medfiles, Raisio Group |
| NCT02644109 | Phase 4 | Oct 1, 2015 | Pontificia Universidad Catolica de Chile, University of Chile |
| NCT02541201 | Phase 2 | Aug 1, 2015 | The University of Hong Kong |
| NCT02230800 | Phase 2 | Jan 1, 2015 | Government of Malaysia, Royal Marsden Hospital NHS Trust |
| NCT02288585 | N/A | Oct 1, 2014 | Commonwealth Scientific and Industrial Research Organisation, Australia, Unilever |
| NCT02221297 | N/A | May 1, 2014 | Clinical Research Institute HUCH Ltd, Raisio Group |
| NCT02065024 | Phase 1 | Mar 1, 2014 | Autonomous University of Madrid |
| NCT02221973 | N/A | Jul 1, 2013 | Nestle |
| NCT02459314 | N/A | Apr 1, 2013 | Chiangmai University |
| NCT01803178 | N/A | Feb 1, 2013 | Unilever |
Showing 20 of 46 trials
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Organizations
Research & Development (59)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Unilever | For profit | 6 | 5 | 1 | 2009 |
| Raisio Group | For profit | 4 | 4 | 1 | 2011 |
| University of Manitoba | Academic/Hospital | 4 | 4 | 4 | 2008 |
| Maastricht University | Academic/Hospital | 3 | 3 | 1 | 2003 |
| Autonomous University of Madrid | Academic/Hospital | 2 | 2 | 1 | 2010 |
| Danone Research | For profit | 2 | 1 | 2 | 2008 |
| Enzymotec | For profit | 2 | 2 | 2 | 2007 |
| Hospital do Coracao | Academic/Hospital | 2 | 2 | 1 | 2023 |
| National Institute of Cardiology, Laranjeiras, Brazil | Government | 2 | 0 | 1 | 2023 |
| The University of Hong Kong | Academic/Hospital | 2 | 2 | 2 | 2015 |
| University of Helsinki | Academic/Hospital | 2 | 1 | 1 | 2006 |
| University of Sao Paulo | Academic/Hospital | 2 | 0 | 1 | 2023 |
| ZonMw: The Netherlands Organisation for Health Research and Development | Academic/Hospital | 2 | 0 | 1 | 2003 |
| Academisch Medisch Centrum | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Boca Raton Community Hospital | Academic/Hospital | 1 | 0 | 1 | 2009 |
| Cargill | For profit | 1 | 0 | 1 | 2004 |
| Chestnut Hill Healthcare | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Chiangmai University | Academic/Hospital | 1 | 1 | 1 | 2013 |
| China Medical University | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Clinical Research Institute HUCH Ltd | Academic/Hospital | 1 | 0 | 1 | 2014 |
59 organizations
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