National Cancer Institute (NCI)
Also known as: Accelerared Community Oncology Research Network, Inc. | Accelerated Community Oncology Reseaerch Network, Inc. (ACORN) | Accelerated Community Oncology Research Network | Accelerated Community Oncology Research Network, Inc. | Accelerated Community Oncology Research Network, Inc. (ACORN) | Alliance for Clinical Trials in Oncology | Alliance for Clinical Trials in Oncology Cancer Control Program (CCP) | Children's Oncology Group | Children's Oncology Group (COG) | COG Phase 1 Consortium | COG Phase I Consortium | Lymphoma Trials Office | National Cancer Institute (NCI) | National Cancer Institute/NIH/DHHS (NCI) | New Approaches to Brain Tumor Therapy Consortium | New Approaches to Neuroblastoma Therapy Consortium | New Approaches to Neuroblastoma Therapy Consortium (NANT) | New Approaches to Neuroblastoma Treatment | New Approaches to Neuroblastoma Treatment (NANT) | North American Brain Tumor Consortium | Pediatric Early Phase Clinical Trial Network | Raghu Nandan, M.D., Inc | The Cancer Therapy Evaluation Program of the National Cancer Institute
Highest phase reached
Phase 4
First clinical trial
Sep 1, 1977Last known activity
Sep 21, 2026
Timeline
1930s
- Aug 5, 1937
National Cancer Institute (NCI)— Founded
Drugs by trial phase (2154 distinct, 9610 trials)
Phase 4 (77 own, 0 via acquisition)
Phase 3 (431 own, 0 via acquisition)
Phase 2 (1000 own, 0 via acquisition)
Phase 1 (563 own, 0 via acquisition)
- 95-5-49
- bizelesin
- il13ralpha2-specific hinge-optimized 4-1bb-co-stimulatory car/truncated cd19-expressing autologous tn/mem cells (Biological)
- pgv001
- iodine i 131 monoclonal antibody cc49-deltach2
- ar-42
- ricolinostat
- imp288
- gene-modified tumor cell vaccine therapy
- allogeneic cd8 t cells
- ttrna-dcs
- 70-kd heat-shock protein
- fowlpox-sargramostim
- proanthocyanidin extract
- pu-h71
- +548 more
Other trials (83 own, 0 via acquisition)
- rutin
- anti-thyroglobulin mtcr-transduced autologous peripheral blood lymphocytes
- gadoteridol
- isopropyl alcohol
- sialyl lewis-keyhole limpet hemocyanin conjugate vaccine
- 18f fp-r01-mg-f2
- ap5346
- misoprostol
- ga 68-edotreotide
- etanidazole
- multi-epitope folate receptor alpha-loaded dendritic cell vaccine
- raltegravir
- cin2/3
- bimatoprost
- acitretin
- +68 more
Indications
Studied for
- Abdominal Neoplasms
- Aberrant Crypt Foci
- Acquired Immunodeficiency Syndrome
- Acrodermatitis
- ACTH-Secreting Pituitary Adenoma
- Acute Disease
- Acute Lung Injury
- Adamantinoma
- Adenocarcinoma
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenocarcinoma, Clear Cell
- Adenocarcinoma, Follicular
- Adenocarcinoma, Mucinous
- Adenocarcinoma of Lung
- Adenocarcinoma, Papillary
- Adenoma
- Adenoma, Acidophil
- Adenoma, Basophil
- Adenoma, Chromophobe
- Adenoma, Islet Cell
- Adenoma, Liver Cell
- Adenomatous Polyposis Coli
- Adenomatous Polyps
- Adenomyoepithelioma
- Adenosarcoma
- Adrenal Cortex Neoplasms
- Adrenal Gland Neoplasms
- Adrenocortical Carcinoma
- Aggression
- AIDS-Related Complex
- Albuminuria
- Ameloblastoma
- Amyloidosis
- Anemia
- Anemia, Aplastic
- Anemia, Diamond-Blackfan
- Anemia, Hemolytic
- Anemia, Hemolytic, Autoimmune
- Anemia, Refractory
- Anemia, Refractory, with Excess of Blasts
- Anemia, Sickle Cell
- Angiomyolipoma
- Anorexia
- Anus Neoplasms
- Anxiety Disorders
- Arsenic Poisoning
- Arthralgia
- Ascites
- Aspergillosis
- Astrocytoma
- Atrophy
- Atypical Squamous Cells of the Cervix
- Autoimmune Diseases
- Autoimmune Diseases of the Nervous System
- Bacterial Infections
- Barrett Esophagus
- Basal Cell Carcinoma
- Basal Cell Nevus Syndrome
- Beckwith-Wiedemann Syndrome
- Behavior, Addictive
- beta-Thalassemia
- Bile Duct Neoplasms
- Biliary Tract Neoplasms
- Birt-Hogg-Dube Syndrome
- Blast Crisis
- Blood Platelet Disorders
- Body Weight
- Body Weight Changes
- Bone Diseases
- Bone Diseases, Metabolic
- Bone Marrow Diseases
- Bone Neoplasms
- Brain Diseases
- Brain Edema
- Brain Neoplasms
- Brain Stem Neoplasms
- Breast Carcinoma In Situ
- Breast Diseases
- Breast Neoplasms
- Breast Neoplasms, Male
- Brenner Tumor
- Bronchiolitis
- Bronchiolitis Obliterans
- Burkitt Lymphoma
- Cachexia
- Calcinosis
- Cancer Pain
- Candidemia
- Candidiasis
- Candidiasis, Oral
- Carcinogenesis
- Carcinoid Tumor
- Carcinoma
- Carcinoma, Acinar Cell
- Carcinoma, Adenoid Cystic
- Carcinoma, Adenosquamous
- Carcinoma, Basosquamous
- Carcinoma, Ductal
- Carcinoma, Ductal, Breast
- Carcinoma, Embryonal
Recent trials (50)
- NCT07288034CollaboratorPhase 2Sep 21, 2026
- NCT07261657CollaboratorEarly Phase 1Sep 2, 2026
- NCT07218692CollaboratorPhase 2Aug 11, 2026
- NCT07012031Lead sponsorPhase 1/Phase 2Aug 7, 2026
- NCT07261241Lead sponsorPhase 2Jul 31, 2026
- NCT06900595Lead sponsorPhase 2Jul 19, 2026
- NCT06900595OfficialPhase 2Jul 19, 2026
- NCT07271355CollaboratorPhase 3Jul 1, 2026
- NCT07275216CollaboratorPhase 2Jul 1, 2026
- NCT06965114Lead sponsorPhase 1/Phase 2Jun 27, 2026
- NCT07226544CollaboratorPhase 2Jun 8, 2026
- NCT07293403CollaboratorPhase 2Jun 7, 2026
- NCT07061964Lead sponsorPhase 2Jun 1, 2026
- NCT06996119CollaboratorPhase 1May 25, 2026
- NCT07020533CollaboratorPhase 1May 8, 2026
Details
- Founded
- Washington, DC, US Aug 5, 1937
- Last known activity
- Sep 21, 2026
Notes
--- Notes from Accelerated Community Oncology Research Network, Inc.: CRO --- --- Notes from Alliance for Clinical Trials in Oncology: formed through merger of: American College of Surgeons Oncology Group (ACOSOG), Cancer and Leukemia Group B (CALGB), and North Central Cancer Treatment Group (NCCTG); sponsored by NCI ---