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Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
Subtype terms (3)
More specific conditions that are subtypes of Reperfusion Injury in the MeSH hierarchy.
- Myocardial Reperfusion Injury
28 drugs (22 approved, 6 experimental)
- Post-Cardiac Arrest Syndrome
14 drugs approved
- Primary Graft Dysfunction
4 drugs (3 approved, 1 experimental)
Drugs by status
Phase 4 trials (20)
Phase 3 trials (12)
Phase 2 trials (25)
- melatonin
- sodium nitrite
- methylprednisolone
- vitamin e
- apotransferrin
- epoetin
- C1 Esterase Inhibitor (Human)
- conjugated equine estrogens
- doxycycline
- valproic acid
- eculizumab
- elamipretide
- liraglutide
- palonosetron
- p-selectin glycoprotein ligand ig fusion protein
- reparixin
- treprostinil
- nicotinamide
- infliximab
- netupitant
- lactic acid
- antithrombin iii (human)
- epoprostenol
- glutathione
- bx-001n
Other trials (25)
- phenylephrine
- beta carotene
- beta-hydroxybutyrate
- c-type natriuretic peptide
- norepinephrine
- alpha-lipoic acid
- copper
- ibuprofen
- diazoxide
- glyburide
- hwangryun
- adenosine
- acetylcholine chloride
- prolycopene
- ursodeoxycholic acid
- cow milk
- aluminum hydroxide
- epinephrine
- tc99m annexin a5
- zinc dichloride
- eplerenone
- morphine
- naloxone
- blood plasma
- selenium
Organizations
Organization Involved with Phase 4 Indications (42)
- Pfizer
- Novartis
- R&D Cardiologie
- Dalian Zhen-Ao Bio-Tech Co., Ltd.
- Japan Heart Foundation
- Baskent University
- Cukurova University
- Evangelismos Hospital
- Georgetown University
- Kumamoto University
- Radboud University
- RWTH Aachen University
- Rutgers University
- University of Toronto
- Utrecht University
- University of Athens
- University of Bern
- University of Zurich
- University of Leipzig
- Capital Medical University
- Istanbul University
- University of Ulsan
- University of Basel
- University of Vienna
- Chungnam National University
- Gyeongsang University
- St. Antonius Hospital, Nieuwegein
- University of Oxford
- Gennimatas Hospital, Athens
- Catholic University of Korea
- +12 more
Organization Involved with Phase 3 Indications (25)
- Medicure
- Genzyme
- Mallinckrodt
- ZonMw: The Netherlands Organisation for Health Research and Development
- University of London
- Harvard University
- Duke University
- University of Washington
- Kyung Hee University
- NHS Lothian
- University of Edinburgh
- University of Leeds
- University of Sussex
- University of Birmingham
- University of Cape Town
- University of Amsterdam
- University of Strasbourg
- British Heart Foundation
- Karolinska Institute
- The Hatter Cardiovascular Institute
- University of Montreal
- Ludwig Maximilians University
- University of Alabama, Birmingham
- Linkoping University
- Basildon and Thurrock University Hospitals NHS Foundation Trust
Organization Involved with Phase 2 Indications (41)
- Trophos
- United Therapeutics
- Fibrex Medical Research & Development GmbH
- GlaxoSmithKline
- Hope Pharmaceuticals
- Y's Therapeutics, Inc.
- Stealth BioTherapeutics Inc.
- Shantou University Medical College
- University of Pennsylvania
- University of Pittsburgh
- Cedars-Sinai Medical Center
- Katholieke Universiteit Leuven
- Johns Hopkins University
- Medical University of Warsaw
- Nanjing University
- Newcastle University
- Rhode Island Hospital
- Russian Academy of Medical Sciences
- University of Hull
- University of Oslo
- University of Rhode Island
- Mayo Clinic
- Peking University
- University of Copenhagen
- Papworth Hospital NHS Foundation Trust
- Istituto Clinico Humanitas - Rozzano (MI), Italy
- National University of Singapore
- Government of Russia
- University of Lyon
- University of Texas, Galveston
- +11 more
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (21)
- World Health Organization
- Shahid Beheshti University of Medical Sciences
- Advocate Health Care
- Aarhus University
- Centre Hospitalier le Mans
- Mansoura University
- University of Essex
- University of Groningen
- Yonsei University
- Republican Scientific and Practical Center for Organ and Tissue Transplantation
- University of California, Los Angeles
- University of Chile
- University of Colorado, Denver
- Vanderbilt University
- Jiao Tong University
- Advocate Healthcare
- Government of Korea
- Thompson Rivers University
- Aristotle University of Thessaloniki
- Pooyesh Darou
- ISTITUTO REGINA ELENA