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Osteoporosis
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
Subtype terms (1)
More specific conditions that are subtypes of Osteoporosis in the MeSH hierarchy.
- Osteoporosis, Postmenopausal
78 drugs (32 approved, 46 experimental)
Drugs by status
Approved for this indication (29)
- denosumab
- tibolone
- romosozumab
- calcium carbonate
- oxandrolone
- abaloparatide
- raloxifene
- eldecalcitol
- etidronic acid
- folic acid
- cyanocobalamin
- arzoxifene
- menaquinone
- Menatetrenone
- alendronic acid
- teriparatide
- risedronate
- strontium ranelate
- estradiol
- zoledronic acid
- pyridoxine
- strontium bromide
- tiludronate
- ibandronate
- recombinant salmon calcitonin
- calcitonin pork
- vitamin k2
- manganese chloride
- Minodronate
Phase 4 trials (46)
- metformin
- vitamin d3
- alfacalcidol
- cinacalcet
- calcium citrate
- fluvastatin
- evogliptin
- dehydroepiandrosterone
- demeclocycline hydrochloride
- progesterone
- valproic acid
- doravirine
- parathyroid hormone
- gliclazide
- liraglutide
- dolutegravir
- tenofovir
- calcium
- carbamazepine
- topiramate
- lamivudine
- pitavastatin
- pamidronate
- atorvastatin
- linagliptin
- valsartan
- acetaminophen
- semaglutide
- emtricitabine
- testosterone
- +16 more
Phase 3 trials (37)
- nitroglycerin
- calcium glucarate
- calcium salts
- odanacatib
- conjugated equine estrogens
- somatropin
- leuprolide
- goserelin
- Hesperedin
- lasofoxifene
- niacin
- progestin
- calcitonin salmon
- sitagliptin
- bevacizumab
- toremifene
- alemtuzumab
- vitamin k
- creatine
- flax
- triptorelin
- bazedoxifene
- corn
- nitric acid
- estrogen
- genistein
- phylloquinone
- buserelin
- tirzepatide
- hesperidin
- +7 more
Phase 2 trials (51)
- simvastatin
- 2-methylene-19-nor-(20s)-1,25-dihydroxyvitamin d3
- norgestrel
- balicatib
- bone morphogenetic protein-2
- bps804
- vitis vinifera
- ethinyl estradiol
- rosuvastatin
- whey protein
- blosozumab
- neridronic acid
- nondigestible oligosaccharide
- ono-5334
- ph3
- donepezil
- ronacaleret
- strontium malonate
- dasatinib
- everolimus
- anastrozole
- thiram
- tocotrienol
- nicotinamide
- xianlinggubao
- zhongyaofufang
- bifidobacterium infantis
- bifidobacterium breve
- bifidobacterium longum
- autologous osteoblasts
- +21 more
Phase 1 trials (34)
- melatonin
- cep-37251
- etanercept
- prenylflavonoids extract
- gusuibu
- magnesium oxide
- hyaluronidase (human recombinant)
- mk0773
- phytosterol
- rn564
- sotatercept
- strontium-89
- collagen
- vancomycin
- umbilical cord mesenchymal stem cells
- blueberry allergenic extract
- chymosin
- fucosylated autologous bone marrow cells
- davallia divaricata
- llp2a-alendronate
- gentamicin
- ketoconazole
- meropenem
- b-cryptoxanthin
- galactooligosaccharide
- calcium chloride
- ad-101
- naquinate
- shr-1222
- JW1601
- +4 more
Other trials (41)
- decitabine
- methylprednisolone
- 99mtc mdp
- clodronate
- atenolol
- deferoxamine
- prednisone
- ibuprofen
- enobosarm
- gabapentin
- bovine colostrum
- bicalutamide
- mecasermin
- dibotermin alpha
- deferiprone
- kefir
- leucine
- levocarnitine
- nebivolol
- vitamin c
- cow milk
- potassium citrate
- propranolol
- resveratrol
- alpha-galacto-oligosaccharides
- moringa oleifera
- phytoestrogens
- polymethylmetacrylate
- prunus domestica
- red clover extract
- +11 more
Organizations
Organization Involved with Phase 4 Indications (109)
- Eisai
- Organon
- Gilead Sciences
- Novo Nordisk
- Pfizer
- Sanofi-Aventis
- Amorphical Ltd.
- Bio Sidus SA
- GlaxoSmithKline
- Hanlim Pharm. Co., Ltd.
- Health Research, Inc.
- Jiangsu Chia-tai Tianqing Pharmaceutical Co.,Ltd
- Nycomed
- Fundacio Lluita Contra la SIDA
- National Institutes of Health (NIH)
- National Institute of Mental Health (NIMH)
- National Institute on Aging (NIA)
- United States Department of Agriculture
- Warner Chilcott
- Hellenic Army
- Aarhus University
- Maastricht University
- University of Pittsburgh
- British Thoracic Society
- CIHR Canadian HIV Trials Network
- Cornell University
- Harvard University
- Duke University
- Helen Hayes Hospital
- Indiana University
- +79 more
Organization Involved with Phase 3 Indications (115)
- Abbott
- Ligand Pharmaceuticals
- Daiichi Sankyo
- Hexal AG
- Takeda
- Shire
- Grunenthal
- Sandoz
- Astellas
- Wyeth
- AryoGen Pharmed Co.
- Bayer
- Chiesi
- Chugai
- Evangelisches Krankenhaus Lutherhaus gGmbH
- GTx
- Hamad Medical Corporation
- NPS Pharma
- Qilu Pharmaceutical Co., Ltd.
- Sponsor GmbH
- Tarsa Therapeutics, Inc.
- Virchow Group
- Alvogen
- EA Pharma Co., Ltd.
- Pfenex, Inc
- Solae, LLC
- Fondazione Telethon
- Ontario Neurotrauma Foundation
- French National Agency for Research on AIDS and Viral Hepatitis
- Medical Research Council
- +85 more
Organization Involved with Phase 2 Indications (60)
- Osteologix
- McNeil
- AstraZeneca
- Genentech
- Genzyme
- Perrigo
- Azelon Pharmaceuticals
- Chavah Pty Ltd
- DSM
- Deltanoid Pharmaceuticals
- Elvir SAS
- Endo Pharmaceuticals
- mdRNA
- PhytoHealth Corporation
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
- TransPharma Medical
- Unigene Laboratories Inc.
- Entera Bio Ltd.
- Otsuka
- Zosano Pharma Inc.
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Laikο General Hospital, Athens
- University of Arizona
- Baylor University
- Azienda Ospedaliera V. Cervello
- Craig Hospital
- Emory University
- Gynecologic Oncology Group
- Korea Health Industry Development Institute
- +30 more
Organization Involved with Phase 1 Indications (45)
- Acceleron Pharma, Inc.
- Cephalon
- Halozyme Therapeutics
- Hengrui Therapeutics, Inc.
- Huons Co.,Ltd.
- Jiangsu T-Mab Biopharma Co.,Ltd
- Parexel
- Red de Terapia Celular
- Yuyu Pharma, Inc.
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
- ZonMw: The Netherlands Organisation for Health Research and Development
- National Center for Research Resources (NCRR)
- Huazhong University of Science and Technology
- Ajou University
- Central South University
- Korea University
- Spanish National Health System
- Universidad de Murcia
- University of Nottingham
- University of Tennessee
- Wageningen University
- Duquesne University
- Fudan University
- University of Colorado, Denver
- University of Copenhagen
- Covance
- Free University of Amsterdam
- WCCT Global
- National University of Singapore
- Centre de Recherche en Nutrition Humaine d'Ile-de-France
- +15 more
Organization Involved with Other Experimental Indications (72)
- Aventis
- BioGaia AB
- TNO
- e-GLORIA trial Protocol Review Committee
- National Institute of Nutrition and Seafood Research, Norway
- Region Syddanmark
- University of Pennsylvania
- Rockefeller University
- Alexandria University
- Appalachian State University
- Cairo University
- Changhua Christian Hospital
- Ciudad Universitaria, Spain
- Florida State University
- Georgetown University
- Johns Hopkins University
- Oregon Health and Science University
- Postgraduate Institute of Medical Education and Research
- Rutgers University
- Shenzhen Third People's Hospital
- Texas A&M University
- Universidad Autonoma de Madrid
- University of Georgia
- University of Kansas
- University of Limerick
- University of Liverpool
- University of Maryland
- University of Nebraska
- University of New Mexico
- University of Rochester
- +42 more