ronacaleret
Small moleculeexperimental
Clinical trial activity
12 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Oct 1, 2006 (NCT00554255)
Timeline
Indications
Mechanism of action
- Calcium sensing receptorANTAGONIST
CASR antagonist
Chemistry & pharmacology
Loading structure…
SMILES
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(CCC(=O)O)cc(F)c1F- Mol. weight
- 447.52 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1198855 ↗
Also known as
- ronacaleret
- ronacaleret
- ronacaleret
- ronacaleret
- sb751689
- sb751689
- sb-751689
- sb-751689
- sb-751689
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01802892 | Phase 1 | Nov 2, 2012 | GlaxoSmithKline |
| NCT01466335 | Phase 1 | Oct 27, 2011 | GlaxoSmithKline |
| NCT00651534 | Phase 1 | Feb 1, 2008 | GlaxoSmithKline |
| NCT00548496 | Phase 2 | Sep 20, 2007 | GlaxoSmithKline |
| NCT00532077 | Phase 1 | Aug 1, 2007 | GlaxoSmithKline |
| NCT00508534 | Phase 1 | Jul 1, 2007 | GlaxoSmithKline |
| NCT00471237 | Phase 2 | May 1, 2007 | GlaxoSmithKline |
| NCT00540878 | Phase 1 | Apr 1, 2007 | GlaxoSmithKline |
| NCT00468689 | Phase 1 | Apr 1, 2007 | GlaxoSmithKline |
| NCT00499928 | Phase 1 | Apr 1, 2007 | GlaxoSmithKline |
| NCT00554255 | Phase 1 | Oct 1, 2006 | GlaxoSmithKline |
| NCT00388596 | Phase 1 | Oct 1, 2006 | GlaxoSmithKline |
Showing 12 of 12 trials
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Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| GlaxoSmithKline | For profit | 12 | 12 | 2 | 2006 |
1 organizations
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