umbilical cord mesenchymal stem cells
Cell therapyexperimental
Clinical trial activity
369 trials · 267 clinical orgs · 0 marketing orgs
Phase 1
251
Phase 2
212
Phase 3
20
Phase 4
3
Earliest trial started Jan 1, 1999 (NCT00029380)
Timeline
Indications
Approved for
Studied for
- Accidents · Phase 1
- Acute Febrile Encephalopathy · Phase 1
- Acute Kidney Injury · Phase 2
- Acute Lung Injury · Phase 1/Phase 2
- Acute-On-Chronic Liver Failure · Phase 3
- Aging · Phase 1/Phase 2
- Alzheimer Disease · Phase 1/Phase 2
- Amyotrophic Lateral Sclerosis · Phase 1/Phase 2
- Anemia · Phase 1/Phase 2
- Anemia, Aplastic · Phase 2
- Anemia, Sickle Cell · Phase 2
- Angina Pectoris · Phase 1/Phase 2
- Arthritis, Rheumatoid · Phase 1/Phase 2
- Asthma · Phase 1/Phase 2
- Autism Spectrum Disorder · Phase 2
- Autistic Disorder · Phase 2
- Autoimmune Diseases · Phase 1/Phase 2
- Basal Ganglia Hemorrhage · Phase 2
- beta-Thalassemia · Phase 2
- Biliary Atresia · Phase 1
- Bone Diseases · Phase 1/Phase 2
- Bone Marrow Failure Disorders · Phase 1/Phase 2
- Brain Infarction · Phase 1/Phase 2
- Brain Ischemia · Phase 1
- Bronchial Fistula · Phase 1
- Bronchopulmonary Dysplasia · Phase 2
- Burns · Phase 1/Phase 2
- Cardiomyopathies · Phase 2
- Cardiomyopathy, Dilated · Phase 1/Phase 2
- Cartilage Diseases · Phase 1/Phase 2
- Central Nervous System Diseases · Phase 1/Phase 2
- Cerebral Hemorrhage · Phase 1
- Cerebral Infarction · Phase 1/Phase 2
- Cerebral Palsy · Phase 2
- Cholangitis, Sclerosing · Phase 1/Phase 2
- Chronic Limb-Threatening Ischemia · Phase 2
- Colitis, Ulcerative · Phase 1/Phase 2
- Colorectal Neoplasms · Early Phase 1
- Congenital Abnormalities · Phase 1
- Corneal Diseases · Phase 1
- Coronary Artery Disease · Phase 1/Phase 2
- Coronavirus · Phase 1/Phase 2
- Coronavirus Infections · Phase 2
- COVID-19 · Phase 3
- Crohn Disease · Phase 3
- Dementia · Phase 1
- Dermatitis, Atopic · Phase 3
- Dermatology · Phase 2/Phase 3
- Dermatomyositis · Early Phase 1
- Diabetes Mellitus · Phase 2
- Diabetes Mellitus, Type 1 · Phase 1/Phase 2
- Diabetes Mellitus, Type 2 · Phase 2
- Diabetic Foot · Phase 1/Phase 2
- Diabetic Nephropathies · Early Phase 1
- Drug-Related Side Effects and Adverse Reactions · Phase 1/Phase 2
- Endothelial Cells · Phase 1/Phase 2
- End Stage Liver Disease · Phase 1/Phase 2
- Epidermolysis Bullosa · Phase 1/Phase 2
- Erectile Dysfunction · Phase 1/Phase 2
- Erythropoietin · Phase 1/Phase 2
- Eye Diseases · Phase 1
- Eye Neoplasms · Phase 1
- Fetal Blood · Phase 1/Phase 2
- Fractures, Bone · Phase 3
- Frailty · Phase 1/Phase 2
- General Surgery · Phase 1
- Gingival Diseases · Phase 4
- Graft vs Host Disease · Phase 3
- Heart Diseases · Phase 1/Phase 2
- Heart Failure · Phase 2
- Heart Failure, Systolic · Phase 1/Phase 2
- Heel · Phase 1
- Hematologic Diseases · Phase 2
- Hematologic Neoplasms · Phase 1/Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 2
- Hemorrhage · Phase 1/Phase 2
- Hepatitis, Autoimmune · Phase 1/Phase 2
- Hepatitis B · Phase 1/Phase 2
- Idiopathic Pulmonary Fibrosis · Phase 1
- Infant, Extremely Premature · Phase 1
- Infant, Premature · Phase 2/Phase 3
- Infarction, Anterior Cerebral Artery · Phase 1/Phase 2
- Infarction, Middle Cerebral Artery · Phase 1/Phase 2
- Infarction, Posterior Cerebral Artery · Phase 1/Phase 2
- Infections · Phase 2
- Infertility, Female · Phase 1
- Inflammation · Phase 2
- Ischemia · Phase 2/Phase 3
- Ischemic Stroke · Phase 2/Phase 3
- Keloid · Phase 4
- Kidney Diseases · Phase 2
- Leukemia, Myeloid, Acute · Phase 1/Phase 2
- Lewy Body Disease · Phase 1
- Lipid Metabolism Disorders · Phase 1/Phase 2
- Liver Cirrhosis · Phase 2
- Liver Cirrhosis, Alcoholic · Phase 1
- Liver Cirrhosis, Biliary · Phase 1/Phase 2
- Liver Failure · Phase 2
- Liver Transplantation · Phase 1
- Lumbar Vertebrae · Phase 1
- Lung Diseases · Early Phase 1
- Lung Diseases, Interstitial · Phase 1
- Lung Injury · Phase 1/Phase 2
- Lupus Erythematosus, Systemic · Phase 3
- Lupus Nephritis · Phase 3
- Machado-Joseph Disease · Phase 2
- Meniscus · Phase 1
- Mesenchymal Stem Cells · Phase 3
- Mesenchymal Stem Cell Transplantation · Phase 1
- Metabolic Syndrome · Phase 1/Phase 2
- Multiple Organ Failure · Phase 1/Phase 2
- Multiple Sclerosis · Phase 1/Phase 2
- Multiple System Atrophy · Phase 1
- Muscular Dystrophy, Duchenne · Phase 1/Phase 2
- Myelodysplastic Syndromes · Phase 2
- Myocardial Infarction · Phase 1/Phase 2
- Myocardial Ischemia · Phase 2
- Myositis · Phase 2/Phase 3
- Nasal Septal Perforation · Phase 1/Phase 2
- Neoplasms · Early Phase 1
- Nephritis, Hereditary · Phase 2/Phase 3
- Neuromyelitis Optica · Phase 1/Phase 2
- Neutropenia · Phase 1/Phase 2
- Obesity · Phase 1/Phase 2
- Organ Transplantation · Phase 1/Phase 2
- Osteoarthritis · Phase 3
- Osteoarthritis, Knee · Phase 3
- Osteonecrosis · Phase 1/Phase 2
- Osteoporosis · Phase 1
- Ovarian Diseases · Phase 1
- Pain · Phase 1
- Papillomaviridae · Phase 1/Phase 2
- Parkinson Disease · Phase 1/Phase 2
- Pathologic Processes · Phase 2
- Peripheral Arterial Disease · Phase 1/Phase 2
- Peripheral Vascular Diseases · Phase 1
- Pharmacokinetics · Phase 1/Phase 2
- Pneumoconiosis · Phase 1
- Pneumonia · Phase 1/Phase 2
- Pneumonia, Ventilator-Associated · Phase 2
- Pneumonia, Viral · Phase 2
- Poisoning · Phase 1/Phase 2
- Polycystic Ovary Syndrome · Phase 1/Phase 2
- Polymyositis · Early Phase 1
- Primary Ovarian Insufficiency · Phase 2
- Psoriasis · Phase 1/Phase 2
- Pulmonary Disease, Chronic Obstructive · Phase 1/Phase 2
- Radiology · Phase 1/Phase 2
- Radiotherapy · Phase 1
- Rectal Diseases · Phase 1
- Rectal Fistula · Phase 1/Phase 2
- Renal Insufficiency, Chronic · Phase 1/Phase 2
- Respiratory Distress Syndrome · Phase 2
- Retinitis Pigmentosa · Phase 2/Phase 3
- Rhinitis, Allergic · Phase 1
- Rhytidoplasty · Phase 1
- Rotator Cuff Injuries · Phase 1/Phase 2
- Safety · Phase 1/Phase 2
- Sclera · Phase 2
- Scleroderma, Systemic · Phase 1/Phase 2
- Sepsis · Phase 2
- Severe Acute Respiratory Syndrome · Phase 2
- Sexual Dysfunction, Physiological · Phase 1/Phase 2
- Shock · Phase 2
- Shock, Septic · Phase 2
- Spinal Cord Injuries · Phase 2
- Spinocerebellar Ataxias · Phase 2
- Spinocerebellar Degenerations · Phase 1/Phase 2
- Spondylitis, Ankylosing · Phase 1
- ST Elevation Myocardial Infarction · Phase 3
- Stem Cells · Phase 4
- Stroke · Phase 2
- Survival Rate · Phase 1
- Sweat Gland Diseases · Phase 1
- Systemic Inflammatory Response Syndrome · Phase 2
- Talus · Phase 3
- Thrombocytopenia · Phase 1/Phase 2
- Traumatology · Phase 2
- Treatment Outcome · Phase 1/Phase 2
- Umbilical Cord · Phase 1/Phase 2
- Uterus · Phase 2
- Ventricular Dysfunction, Left · Phase 1/Phase 2
- Wounds and Injuries · Phase 1/Phase 2
Mechanism of action
- LungTissue restoration
Lung tissue restoration
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL6068203 ↗
Also known as
- allogeneic umbilical cord mesenchymal stem cells
- allogeneitc umbilical cord mesenchymal stem cells
- cartistem
- dehydrated human umbilical cord allograft
- furestem
- human umbilical cord blood-derived mesenchymal stem cells
- human umbilical cord derived mesencymal stem cells
- human umbilical cord mesenchymal stem cells
- human umbilical cord tissue-derived mesenchymal stromal cells
- sangstat
- umbilical cord blood mesenchymal stem cells
- umbilical cord derived mesenchymal stem cells
- umbilical cord-derived mesenchymal stem cells
- umbilical cord mesenchymal stem cells
- umbilical cord tissue-derived mesenchymal stem cells
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07075315 | Phase 3 | Jan 31, 2028 | Indian Council of Medical Research, Institute of Liver and Biliary Sciences, India |
| NCT07131306 | Phase 2 | Jan 31, 2027 | Indian Council of Medical Research, Institute of Liver and Biliary Sciences, India |
| NCT07144072 | Phase 1 | Jan 31, 2026 | Hexun Biosciences Co., LTD. |
| NCT07131540 | Phase 1 | Jan 31, 2026 | Indian Council of Medical Research, Institute of Liver and Biliary Sciences, India |
| NCT07304440 | N/A | Jan 15, 2026 | Adia Med of Winter Park LLC |
| NCT07313020 | Early Phase 1 (Phase 1) | Dec 16, 2025 | Soochow University |
| NCT07232563 | Phase 1 | Dec 1, 2025 | Southern Medical University |
| NCT07137104 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2025 | Hexun Biosciences Co., LTD. |
| NCT07265349 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2025 | Tasly Pharmaceuticals, Inc. |
| NCT07160205 | Phase 2/Phase 3 (Phase 3) | Nov 30, 2025 | Restem, LLC. |
| NCT07086521 | Phase 1 | Oct 31, 2025 | Restem, LLC. |
| NCT07058025 | Phase 2 | Oct 1, 2025 | Canadian Institutes of Health Research (CIHR), Stem Cell Network, University of Ottawa |
| NCT07175207 | Early Phase 1 (Phase 1) | Oct 1, 2025 | Chinese Academy of Medical Sciences |
| NCT07177456 | Early Phase 1 (Phase 1) | Oct 1, 2025 | Chinese Academy of Medical Sciences |
| NCT07197606 | Phase 2 | Oct 1, 2025 | IxCell Biotechnology |
| NCT06984497 | N/A | Sep 30, 2025 | People's Liberation Army of China |
| NCT07084012 | Phase 2 | Aug 27, 2025 | Capital Medical University, Government of China |
| NCT07041801 | Phase 1/Phase 2 (Phase 2) | Jun 28, 2025 | Beike Biotech |
| NCT07011199 | Phase 1 | Jun 17, 2025 | Diponegoro University |
| NCT06954740 | Phase 2 | Jun 10, 2025 | People's Liberation Army of China |
Showing 20 of 369 trials
Page 1 / 19
Organizations
Research & Development (267)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| People's Liberation Army of China | Government | 44 | 37 | 4 | 2009 |
| Huazhong University of Science and Technology | Academic/Hospital | 23 | 19 | 4 | 2018 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 19 | 11 | 3 | 2012 |
| Medipost Co Ltd. | For profit | 14 | 11 | 4 | 2008 |
| Nanjing University | Academic/Hospital | 14 | 6 | 3 | 2010 |
| Sclnow Biotechnology Co., Ltd. | For profit | 14 | 14 | 2 | 2017 |
| Sun Yat-Sen University | Academic/Hospital | 12 | 7 | 3 | 2013 |
| Duke University | Academic/Hospital | 10 | 9 | 2 | 1999 |
| Prodia StemCell Indonesia | For profit | 10 | 9 | 2 | 2018 |
| Beike Biotech | For profit | 9 | 9 | 1 | 2009 |
| Government of China | Government | 9 | 6 | 4 | 2011 |
| Jiao Tong University | Academic/Hospital | 8 | 2 | 3 | 2009 |
| Kang Stem Biotech Co., Ltd. | For profit | 8 | 8 | 3 | 2013 |
| University of Indonesia | Academic/Hospital | 8 | 5 | 5 | 2015 |
| Qingdao University | Academic/Hospital | 7 | 7 | 2 | 2010 |
| Sungkyunkwan University | Academic/Hospital | 7 | 4 | 3 | 2008 |
| The Marcus Foundation | Academic/Hospital | 7 | 0 | 3 | 2017 |
| Translational Biosciences | For profit | 7 | 7 | 1 | 2013 |
| Wuhan University | Academic/Hospital | 7 | 4 | 2 | 2020 |
| Capital Medical University | Academic/Hospital | 6 | 2 | 2 | 2019 |
267 organizations
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