manganese chloride

Small moleculeapproved

Approved

Jun 26, 1986

Manganese Bromide is a highly water soluble crystalline salt composed of manganese and bromine with the formula MnBr2. Manganese Bromide can be used in place of palladium in the Stille reaction, which couples two carbon atoms using an organotin compound — NCATS

Clinical trial activity

8 trials · 4 clinical orgs · 3 marketing orgs

Phase 1
5
Phase 2
5
Phase 3
3
Phase 4
0

Earliest trial started Sep 1, 2017 (NCT02393183)

Timeline

1800s

  1. Jan 1, 1800

    Evidence of US Marketing

1980s

  1. Jun 26, 1986

    Earliest FDA Approval

  2. Jun 26, 1986

    Hospira — NDA Secondary Org

1990s

  1. Dec 19, 1997

    Bracco — First NDA Organization

  2. Dec 19, 1997

    Bracco — NDA Secondary Org

  3. Dec 19, 1997

    Bracco — NDA Organization

2010s

  1. Jan 1, 2017

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2018

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2019

    Earliest Phase 3 Sponsor(trial)

2020s

  1. Jul 7, 2025

    Fresenius — Marketing Organization

Indications

Mechanism of action

Approval history

  • approvedPriority reviewJun 26, 1986
  • approvedJan 1, 1800

Chemistry & pharmacology

Loading structure…

SMILES

[Cl-].[Cl-].[Mn+2]
Mol. weight
125.84 g/mol
Chirality
Achiral Molecule
Inorganic
Yes
Polymer
No
Delivery
Oral, Parenteral
Availability
Prescription Only

Oral

Yes

Parenteral

Yes

Topical

No

Sources

Also known as

  • lumenhance
  • lumenhance
  • lumenhance
  • manganese chloride
  • manganese chloride
  • manganese chloride
  • manganese chloride
  • manganese chloride
  • manganese chloride
  • manganese chloride
  • manganese chloride, 52mn-labeled
  • manganese chloride, diammoniate
  • manganese chloride, dihydrate
  • manganese chloride, hexaammoniate
  • manganese chloride, hexahydrate
  • manganese chloride (mncl2)
  • manganese chloride, monoammoniate
  • manganese chloride tetrahydrate
  • manganese chloride tetrahydrate
  • manganese chloride tetrahydrate
  • manganese chloride tetrahydrate
  • manganese chloride tetrahydrate
  • manganese chloride, tetrahydrate
  • manganese dichloride
  • manganese dichloride
  • manganous chloride
  • manganous chloride
  • mncl2

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04873440Phase 1/Phase 2 (Phase 2)May 6, 2021People's Liberation Army of China
NCT04119843Phase 3Nov 30, 2019Ascelia Pharma AB, Humboldt University
NCT04004234Phase 1/Phase 2 (Phase 2)Mar 1, 2019People's Liberation Army of China
NCT03989310Phase 1/Phase 2 (Phase 2)Mar 1, 2019People's Liberation Army of China
NCT03989336Phase 1/Phase 2 (Phase 2)Mar 1, 2019People's Liberation Army of China
NCT03991559Phase 1Nov 1, 2018People's Liberation Army of China
NCT02393183Phase 2/Phase 3 (Phase 3)Sep 1, 2017Isfahan University
NCT02422368Phase 2/Phase 3 (Phase 3)Sep 1, 2017Isfahan University
Showing 8 of 8 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
People's Liberation Army of ChinaGovernment5522018
Isfahan UniversityAcademic/Hospital2212017
Ascelia Pharma ABFor profit1112019
Humboldt UniversityAcademic/Hospital1012019
4 organizations
Page 1 / 1

Marketing (4)

OrganizationOrg typeRelationshipDate
BraccoFor profitNDA2Dec 19, 1997
BraccoFor profitNDADec 19, 1997
FreseniusFor profitMKTGJul 7, 2025
HospiraFor profitNDA2Jun 26, 1986