neridronic acid
Small moleculeexperimental
Neridronic acid is a bisphosphonate. In Italy it is used to treat osteogenesis imperfecta and Paget's disease of bone. — Wikipedia
Clinical trial activity
6 trials · 9 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
5
Phase 3
4
Phase 4
0
Earliest trial started Jan 1, 2004 (NCT01140321)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
Unclear
Chemistry & pharmacology
Loading structure…
SMILES
NCCCCCC(O)(P(=O)(O)O)P(=O)(O)O- Mol. weight
- 277.15 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaNeridronic acid ↗
- ChEMBLCHEMBL55214 ↗
Also known as
- 6-ahhdp
- 6-amino-1-hydroxyhexane-1,1-diphosphonate
- 6-amino-1-hydroxyhexylidene-1,1-bisphosphonic acid
- (6-amino-1-hydroxyhexylidene)diphosphonic acid
- (6-amino-1-hydroxyhexylidene)diphosphonic acid
- ahhexbp
- aminohexane bisphosphonate
- neridronate
- neridronate
- neridronate
- neridronate
- neridronate
- neridronic acid
- neridronic acid
- neridronic acid
- neridronic acid
- neridronic acid
- neridronic acid
- neridronic acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03560986 | Phase 3 | May 31, 2018 | Grunenthal |
| NCT03530345 | Phase 3 | May 30, 2018 | Grunenthal |
| NCT02972359 | Phase 3 | Dec 20, 2016 | Grunenthal |
| NCT02402530 | Phase 2/Phase 3 (Phase 3) | Apr 1, 2015 | Grunenthal |
| NCT01803360 | Phase 2 | Mar 1, 2013 | ASST Gaetano Pini-CTO, Istituto Ortopedico Gaetano Pini |
| NCT01140321 | Phase 2 | Jan 1, 2004 | Azienda Ospedaliera V. Cervello, Azienda Ospedaliera Villa Sofia, Ospedale Maggiore San Giovanni Bosco, Ospedale Perrino Brindisi, University of Campania Luigi Vanvitelli, University of Genoa |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (9)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Grunenthal | For profit | 4 | 4 | 1 | 2015 |
| ASST Gaetano Pini-CTO | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Azienda Ospedaliera V. Cervello | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Azienda Ospedaliera Villa Sofia | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Istituto Ortopedico Gaetano Pini | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Ospedale Maggiore San Giovanni Bosco | Academic/Hospital | 1 | 0 | 1 | 2004 |
| Ospedale Perrino Brindisi | Academic/Hospital | 1 | 0 | 1 | 2004 |
| University of Campania Luigi Vanvitelli | Academic/Hospital | 1 | 0 | 1 | 2004 |
| University of Genoa | Academic/Hospital | 1 | 1 | 1 | 2004 |
9 organizations
Page 1 / 1